Locations of ART Clinics in the United States and Puerto Rico, 2013 - PowerPoint PPT Presentation

Locations of ART Clinics in the United States and Puerto Rico, 2013 Number of ART clinics in the United States in 2013 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 497 Number of ART clinics that submitted data in 2013 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 467 Total number of ART cycles started in 2013 at clinics reporting data . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190,773 * Number of live-birth deliveries resulting from ART cycles started in 2013 . . . . . . . . . . . . . . . . . . . . . . . . 54,323 Number of infants born as a result of ART cycles started in 2013. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67,996 * This number includes 27,564 cycles with the intent to freeze and bank all resulting eggs or embryos. The remaining 163,209 cycles in 2013 were performed with the intent to transfer at least one egg or embryo, and this is the number of cycles from which data for live- birth deliveries and infants born are based. The 190,773 total cycles in 2013 does not include 67 cycles in which a new treatment procedure was being evaluated.

Types of ART Cycles—United States, * 2013 Frozen egg 1.4% New treatment Frozen donor 5.4% (2,655 cycles) procedure <0.1% (10,270 cycles) (67 cycles) Fresh donor 5.1% (9,718 cycles) Egg/embryo Fresh nondonor banking 14.4% 49.1% (27,564 cycles) (93,787 cycles) Frozen nondonor 24.5% (46,779 cycles) * Total does not equal 100% due to rounding.

ART Use by Age Group—United States, *† 2013 Age: >44 5.4% Age: 43–44 6.9% Age: 41–42 Age: <35 10.8% 37.5% Age: 38–40 19.1% Age: 35–37 20.2% * Based on 190,773 cycles. † Total does not equal 100% due to rounding.

Types of ART Cycles by Age Group—United States, * 2013 100 97% 94% 89% (34) (34) (28) 80% 80 73% (21) (42) 63% 60 Percent (15) (63) (61) (60) (59) (48) 40 38% (19) 27% (31) 20% (10) 20 (10) 10% (19) (17) 6% (5) 4% (10) (5) 0 <35† 35–37 38–40† 41–42 43–44† >44 Age (years) Fresh nondonor Fresh donor Frozen nondonor Frozen donor * Percentages of ART cycles that used fresh or frozen embryos from nondonor or donor eggs are in parentheses. † Total does not equal 100% due to rounding.

Percentages of ART Cycles That Resulted in Live Births, by Type of ART and Clinic Size—United States, 2013 60 50 50 49 50 44 38 38 40 36 36 35 35 33 33 Percent 31 30 30 28 30 20 10 0 <88 88–180 181–409 >409 Clinic Size (number of ART cycles performed in 2013) Fresh nondonor Frozen nondonor Fresh donor Frozen donor

Outcomes of ART Cycles Using Fresh Nondonor Eggs or Embryos, by Stage, 2013 100,000 93,787 cycles 84,868 80,000 started retrievals 73,571 transfers 60,000 Number 40,000 33,425 pregnancies 27,406 20,000 live-birth deliveries 0

Reasons ART Cycles Using Fresh Nondonor Eggs or Embryos Were Canceled, * 2013 Over response to Concurrent illness ovarian stimulation 1.1% medication 3.5% Patient withdrawal for other reasons 11.6% No or not enough egg production 83.8% * Based on 8,919 ART cycles.

Percentages of ART Cycles and Transfers Using Fresh Nondonor Eggs or Embryos That Resulted in Pregnancies, Live Births, and Single-Infant Live Births, 2013 50 45.4 40 37.3 35.6 29.2 30 27.3 Percent 21.4 20 10 0 Pregnancies Live births Single-infant live births Cycles Transfers

Outcomes of ART Cycles Using Fresh Nondonor Eggs or Embryos, 2013 Not able to determine number of fetuses 2.2% Ectopic pregnancy 0.7% Multiple- fetus Clinical pregnancy pregnancy 35.6% 9.9% Single-fetus pregnancy 23.5% No pregnancy 63.7%

Outcomes of Pregnancies That Resulted from ART Cycles Using Fresh Nondonor Eggs or Embryos, *† 2013 Unknown Induced abortion 0.7% 0.9% Miscarriage 15.8% Stillbirth 0.5% Total live births 82.0% Multiple-infant Single-infant birth birth 60.2% 21.8% * Maternal deaths prior to birth are not displayed due to small number (n = 5). † Total does not equal 100% due to rounding.

Distribution of Multiple-Fetus Pregnancies and Multiple-Infant Live Births Among ART Cycles Using Fresh Nondonor Eggs or Embryos, 2013 Triplets or more 1.6% Triplets or more Twins Not able to Twins 0.9% 25.7% determine 26.1% number of fetuses 6.3% Single Single infants fetuses 66.0% 73.4% A. 33,425 pregnancies B. 27,406 live births

Percentages of Preterm Infants or Infants with Low Birth Weight from ART Cycles Using Fresh Nondonor Eggs or Embryos, by Number of Infants Born, 2013 95.8 100 92.3 80 57.8 56.2 60 Percent 40 17.3 17.1 20 11.3 9.0 0 Single infants Single infants Twins Triplets or more from single-fetus from multiple-fetus pregnancies pregnancies Number of Infants Born Preterm infants Low birth weight infants

Age Distribution of Women Who Had ART Cycles Using Fresh Nondonor Eggs or Embryos, 2013 10 9 8 7 6 Percent 5 4 3 2 1 0 <24 24 26 28 30 32 34 36 38 40 42 44 46 48 >48 Age (years) Mean Median

Percentages of ART Cycles Using Fresh Nondonor Eggs or Embryos That Resulted in Pregnancies, Live Births, and Single-Infant Live Births, by Age of Woman, * 2013 60 50 40 Percent 30 20 10 0 <24 24 26 28 30 32 34 36 38 40 42 44 >44 Age (years) Pregnancies Live births Single-infant live births * For consistency, all percentages are based on cycles started.

Percentages of ART Cycles Using Fresh Nondonor Eggs or Embryos That Resulted in Pregnancies, Live Births, and Single-Infant Live Births Among Women Aged 40 or Older, * 2013 30 25 21 20 17 Percent 16 14 13 12 11 9 10 8 8 6 6 4 3 3 2 1 0 40 41 42 43 44 > 44 Age (years) Pregnancies Live births Single-infant live births * For consistency, all percentages are based on cycles started.

Percentages of ART Cycles Using Fresh Nondonor Eggs or Embryos That Resulted in Miscarriage, by Age of Woman, 2013 60 50 40 Percent 30 20 10 0 <24 24 26 28 30 32 34 36 38 40 42 44 >44 Age (years)

Outcomes of ART Cycles Using Fresh Nondonor Eggs or Embryos, by Stage and Age Group, 2013 100 94 91 88 84 84 82 80 76 80 75 69 64 60 54 Percent 46 40 38 40 32 29 21 19 20 11 10 5 4 2 0 <35 35–37 38–40 41–42 43–44 >44 Age (years) Retrieval Transfer Pregnancy Live birth

Percentages of ART Cycles Using Fresh Nondonor Eggs or Embryos, by Infertility Diagnosis, * 2013 40 34.8 29.5 30 Percent 17.5 20 14.7 14.4 13.2 12.9 11.0 9.5 10 4.9 0 Diagnosis * Total percentages are greater than 100% because more than one diagnosis can be reported for each cycle.

Percentages of ART Cycles Using Fresh Nondonor Eggs or Embryos That Resulted in Live Births, by Infertility Diagnosis, 2013 40 37.3 33.6 33.3 31.3 28.5 28.3 30 24.0 23.2 Percent 21.9 17.4 20 10 0 Diagnosis

Percentages of ART Cycles Using Fresh Nondonor Eggs or Embryos That Resulted in Live Births, by Age Group and Number of Previous Live Births, 2013 50 42 40 38 40 34 33 31 30 Percent 24 21 20 20 12 12 11 10 6 5 4 2 2 1 0 <35 35–37 38–40 41–42 43–44 >44 Age (years) No previous live births 1 previous live birth 2 or more previous live births

Percentages of ART Cycles Using Fresh Nondonor Eggs or Embryos That Resulted in Live Births, by Age Group and History of Miscarriage, Among Women with No Previous Births, * 2013 50 39.8 38.6 40 30.8 30.4 30 Percent 20.7 19.9 20 12.6 9.4 10 6.0 4.3 1.8 1.3 0 <35 35–37 38–40 41–42 43–44 >44 Age (years) No previous pregnancies 1 or more previous miscarriages * Women reporting only previous ectopic pregnancies or pregnancies that ended in induced abortion are not included.

Percentages of ART Cycles Using Fresh Nondonor Eggs or Embryos That Resulted in Live Births, by Age Group and Number of Previous ART Cycles, Among Women with No Previous Live Births, 2013 50 42 40 35 33 32 29 28 30 27 Percent 22 22 19 18 18 20 11 11 11 9 10 5 5 5 5 3 2 1 1 0 <35 35–37 38–40 41–42 43–44 >44 Age (years) No previous cycles 1 previous cycle 2 previous cycles 3 or more previous cycles

Percentages of Retrievals Using Fresh Nondonor Eggs or Embryos That Used ICSI, 2013 95.1 100 93.7 93.3 92.6 92.3 91.2 78.0 80 72.1 68.6 67.2 65.6 65.5 60 Percent 40 20 0 <35 35–37 38–40 41–42 43–44 >44 Age (years) ICSI, with male factor ICSI, no male factor

Percentages of Fresh Nondonor Retrievals That Resulted in Live Births Among Patients with or Without Diagnosed Male Factor Infertility, by Age Group and Use of ICSI, * 2013 50 45 43 39 40 37 36 33 30 Percent 26 26 23 20 15 15 12 8 10 6 6 3 2 2 0 <35 35–37 38–40 41–42 43–44 >44 Age (years) ICSI, with male factor ICSI, no male factor No ICSI, no male factor * Cycles using donor sperm and cycles using GIFT or ZIFT are excluded.

Numbers of Embryos Transferred Among All Transfers Using Fresh Nondonor Eggs or Embryos, * 2013 Seven or more Six Zero or unknown 0.1% Five 0.3% <0.1% 1.5% Four 4.0% One Three 23.6% 14.6% Two 55.7% * Total does not equal 100% due to rounding.