Figures from the 2014 Assisted Reproductive Technology National - PowerPoint PPT Presentation

Figures from the 2014 Assisted Reproductive Technology National Summary Report

Locations of ART Clinics in the United States and Puerto Rico, 2014 Number of ART clinics in the United States in 2014 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 498 Number of ART clinics that submitted data in 2014 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 458 Total number of ART cycles started in 2014 at clinics reporting data . . . . . . . . . . . . . . . . . . . . . . . . . . . . 208,604 * Number of live-birth deliveries resulting from ART cycles started in 2014 . . . . . . . . . . . . . . . . . . . . . . . . 57,323 Number of infants born as a result of ART cycles started in 2014. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70,354 * Total includes 35,406 cycles with the intent to freeze all eggs or embryos. Live-birth deliveries and infants born are based on remaining 173,198 cycles with intent to transfer at least one egg or embryo. This includes 3,596 cycles with intent to fertilize previously frozen eggs and transfer resulting embryos. This does not include 26 cycles evaluating a new treatment procedure.

Types of ART Cycles—United States, * 2014 Frozen egg 1.7% New treatment (3,596 cycles) Fresh donor 4.1% procedure <0.1% (8,507 cycles) (26 cycles) Frozen donor embryo 5.7% (11,974 cycles) Egg/embryo Fresh nondonor banking 17.0% 44.5% (35,406 cycles) (92,862 cycles) Frozen nondonor embryo 27.0% (56,259 cycles) * Total does not equal 100% due to rounding.

ART Use by Age Group—United States, *† 2014 Age: >44 5.8% Age: 43–44 7.0% Age: <35 Age: 41–42 37.6% 10.2% Age: 38–40 19.1% Age: 35–37 20.4% * Based on 208,604 cycles. † Total does not equal 100% due to rounding.

Types of ART Cycles by Age Group—United States, * 2014 100 96% 95% 90% (38) (39) 81% (33) 80 (24) 68% 65% (44) 60 (17) Percent (58) (57) (57) (56) (48) 40 35% 31% (20) (9) 18% 20 (24) (22) 10% (10) 5% (15) 4% (5) (8) (5) 0 <35 35–37 38–40 41–42† 43–44 >44† Age (years) Fresh nondonor Fresh donor Frozen nondonor Frozen donor * Percentages of ART cycles that used fresh or frozen embryos from nondonor or donor eggs are in parentheses. † Totals do not equal 100% due to rounding.

Percentages of ART Cycles That Resulted in Live Births, by Type of ART and Clinic Size—United States, 2014 60 50 49 50 47 46 40 40 40 39 38 40 37 37 33 Percent 29 28 28 30 26 20 10 0 <97 97–202 203–434 >434 Clinic Size (number of ART cycles performed in 2014) Fresh nondonor Frozen nondonor Fresh donor Frozen donor

Outcomes of ART Cycles Using Fresh Nondonor Eggs or Embryos, by Stage, 2014 100,000 92,862 cycles 80,000 83,114 started retrievals 67,070 60,000 transfers Number 40,000 30,647 pregnancies 25,016 20,000 live-birth deliveries 0

Reasons ART Cycles Using Fresh Nondonor Eggs or Embryos Were Canceled, *† 2014 Concurrent illness Over response to 1.0% ovarian stimulation medication 4.9% Patient withdrawal for other reasons 11.6% No or not enough egg production 82.4% * Based on 9,748 ART cycles. † Total does not equal 100% due to rounding.

Percentages of ART Cycles and Transfers Using Fresh Nondonor Eggs or Embryos That Resulted in Pregnancies, Live Births, and Single-Infant Live Births, 2014 50 45.7 40 37.3 33.0 28.3 30 26.9 Percent 20.4 20 10 0 Pregnancies Live births Single-infant live births Cycles Transfers

Outcomes of ART Cycles Using Fresh Nondonor Eggs or Embryos, 2014 Not able to determine number of fetuses 2.2% Ectopic pregnancy 0.6% Multiple- fetus Clinical pregnancy pregnancy 33.0% 8.3% Single-fetus pregnancy 22.5% No pregnancy 66.4%

Outcomes of Pregnancies That Resulted from ART Cycles Using Fresh Nondonor Eggs or Embryos, *† 2014 Unknown Induced abortion 0.6% 0.9% Miscarriage 16.2% Stillbirth 0.6% Total live births Multiple-infant 81.6% Single-infant birth birth 61.8% 19.8% * Maternal deaths prior to birth are not displayed due to small number of cycles. † Total does not equal 100% due to rounding.

Distribution of Multiple-Fetus Pregnancies and Multiple-Infant Live Births Among ART Cycles Using Fresh Nondonor Eggs or Embryos, 2014 Triplets or more 1.5% Triplets or Twins more Not able to Twins 23.3% 0.9% determine 23.7% number of fetuses 6.7% Single Single fetuses infants 68.1% 75.7% A. 30,647 pregnancies B. 25,016 live births* * Total does not equal 100% due to rounding.

Percentages of Preterm Infants or Infants with Low Birth Weight from ART Cycles Using Fresh Nondonor Eggs or Embryos, by Number of Infants Born, 2014 98.7 100 93.7 80 56.8 55.4 60 Percent 40 16.8 20 14.9 10.9 9.0 0 Single infants Single infants Twins Triplets or more from single-fetus from multiple-fetus pregnancies pregnancies Number of Infants Born Preterm infants Low birth weight infants

Age Distribution of Women Who Had ART Cycles Using Fresh Nondonor Eggs or Embryos, 2014 10 9 8 7 6 Percent 5 4 3 2 1 0 <24 24 26 28 30 32 34 36 38 40 42 44 46 48 >48 Age (years) Mean Median

Percentages of ART Cycles Using Fresh Nondonor Eggs or Embryos That Resulted in Pregnancies, Live Births, and Single-Infant Live Births, by Age of Woman, * 2014 50 40 30 Percent 20 10 0 <24 24 26 28 30 32 34 36 38 40 42 44 >44 Age (years) Pregnancies Live births Single-infant live births * For consistency, all percentages are based on cycles started.

Percentages of ART Cycles Using Fresh Nondonor Eggs or Embryos That Resulted in Pregnancies, Live Births, and Single-Infant Live Births Among Women Aged 40 or Older, * 2014 30 23 20 18 Percent 16 15 13 11 10 9 10 8 7 6 5 4 3 2 2 1 1 0 40 41 42 43 44 >44 Age (years) Pregnancies Live births Single-infant live births * For consistency, all percentages are based on cycles started.

Percentages of ART Cycles Using Fresh Nondonor Eggs or Embryos That Resulted in Miscarriage, by Age of Woman, 2014 70 60 50 Percent 40 30 20 10 0 <24 24 26 28 30 32 34 36 38 40 42 44 >44 Age (years)

Outcomes of ART Cycles Using Fresh Nondonor Eggs or Embryos, by Stage and Age Group, 2014 100 94 90 87 83 81 78 76 80 75 70 62 60 55 Percent 43 40 37 36 40 30 27 19 16 20 10 9 4 3 1 0 <35 35–37 38–40 41–42 43–44 >44 Age (years) Retrieval Transfer Pregnancy Live birth

Percentages of ART Cycles Using Fresh Nondonor Eggs or Embryos, by Type of Infertility Diagnosis, * 2014 40 35.1 30.8 30 Percent 17.9 20 14.2 14.1 13.7 12.4 11.2 9.3 10 5.5 0 Diagnosis * Total percentages are greater than 100% because more than one diagnosis can be reported for each cycle.

Percentages of ART Cycles Using Fresh Nondonor Eggs or Embryos That Resulted in Live Births, by Type of Infertility Diagnosis, 2014 40 32.9 32.3 30.5 29.0 30 27.1 24.9 Percent 21.8 20.6 18.7 20 14.6 10 0 Diagnosis

Percentages of ART Cycles Using Fresh Nondonor Eggs or Embryos That Resulted in Live Births, by Age Group and Number of Previous Live Births, 2014 50 40 39 40 36 33 32 29 30 Percent 23 22 18 20 11 9 9 10 5 4 3 2 1 1 0 <35 35–37 38–40 41–42 43–44 >44 Age (years) No previous live births 1 previous live birth 2 or more previous live births

Percentages of ART Cycles Using Fresh Nondonor Eggs or Embryos That Resulted in Live Births, by Age Group and History of Miscarriage, Among Women with No Previous Births, * 2014 50 40 36.9 34.7 29.1 28.3 30 Percent 18.8 17.6 20 9.5 9.2 10 3.5 3.1 1.1 1.0 0 <35 35–37 38–40 41–42 43–44 >44 Age (years) No previous pregnancies 1 or more previous miscarriages * Women reporting only previous ectopic pregnancies or pregnancies that ended in induced abortion are not included.

Percentages of ART Cycles Using Fresh Nondonor Eggs or Embryos That Resulted in Live Births, by Age Group and Number of Previous ART Cycles, Among Women with No Previous Live Births, 2014 50 39 40 32 31 30 30 Percent 26 26 26 22 20 20 17 16 14 10 10 8 10 7 5 3 3 2 2 1 1 0 0 <35 35–37 38–40 41–42 43–44 >44 Age (years) No previous cycles 1 previous cycle 2 previous cycles 3 or more previous cycles

Percentages of Retrievals Using Fresh Nondonor Eggs or Embryos That Used ICSI, 2014 100 94.9 93.5 93.2 92.5 90.2 88.8 77.6 80 73.9 70.9 69.0 67.5 66.8 60 Percent 40 20 0 <35 35–37 38–40 41–42 43–44 >44 Age (years) ICSI, with male factor ICSI, no male factor

Percentages of Fresh Nondonor Retrievals That Resulted in Live Births Among Patients with or Without Diagnosed Male Factor Infertility, by Age Group and Use of ICSI, * 2014 50 41 41 38 40 36 34 32 30 Percent 24 24 21 20 14 12 11 10 6 5 4 1 1 1 0 <35 35–37 38–40 41–42 43–44 >44 Age (years) ICSI, with male factor No ICSI, no male factor ICSI, no male factor * Cycles using donor sperm and cycles using GIFT or ZIFT are excluded.