Pawel K. Olszewski, PhD pawel@waikato.ac.nz TEAM TEAM TEAM TEAM - PowerPoint PPT Presentation

Pawel K. Olszewski, PhD pawel@waikato.ac.nz

TEAM TEAM TEAM TEAM TEAM TEAM TEAM TEAM TEAM TEAM Pawel K. Olszewski, PhD Anica Klockars, PhD Kerry Allen, MSc Doctoral students Florence Herisson, MSc Sarah Gartner, MSc Oscar Klockars, MSc Masters students Chloe Brunton, BSc Fraser Aidney, BSc Crystal Gerring, BSc Ron Blaza, BSc Kathryn Laloli, BSc Kiriana Isgrove, BSc

Appetite regulation Food Organism Energy, composition, taste Hunger, reward, anxiety, and availability health/social status, age

Appetite regulation High-throughput animal models

Appetite regulation High-throughput animal models hunger satiety reward stress boredom depression social context aversion

Appetite regulation High-throughput animal models Ad libitum eating Meal (time-restricted; volume-restricted) Deprivation-induced eating Re-feeding Neophobia Taste aversion Motivation to obtain food Standard food Palatable food (single-nutrient; composite) Non-standard mixed diets (powdered, fluids) Healthy Obese/underweight Susceptible to diseases (strains, KOs)

In vivo pharmacology Effect of administered nutrient on select behavioural and physiological parameters Effect of select drugs on intake of specific diets

Diet-induced behavioural, cognitive and physiological parameters Memory Learning Sociability Locomotion Anxiety Depression Peripheral hormone levels

Diet-induced changes in expression of relevant genes Effect of standard vs high-sugar diet intake on expression of hunger and satiety-related genes

Diet- or drug-induced changes in activity of specific brain areas Effect of intake of anxiogenic versus anxiolytic diet on activity of AMY

Diet- or drug-induced changes in activity of specific brain areas High-fat High-sugar Effect of intake of high-fat versus high-sugar diet on activity of oxytocin neurons