Neuroanatomy I: Structures Marc Norman, Ph.D., ABPP Amanda Gooding, Ph.D., ABPP Department of Psychiatry Neuropsychology Clinical Training Seminar (NCTS) 1 https://www.cognitivemedicinegroup.com
About NCTS • Year-long didactic course for trainees • Topics include: neuroanatomy, neuropathology, clinical syndromes, psychometrics, data interpretation, neuroimaging (MRI, MRA, SPECT, PET), behavioral neurology, and professional and practice issues (e.g., case reviews, ABCN-style fact finding exercises, etc.). • Typically, NCTS is offered only to UCSD clinical trainees; however, we are interested in potentially expanding our didactic series to a broader audience. – In particular, we are striving to promote equity, diversity, and inclusion in training, recruitment, and sponsorship of emerging scientist practitioners. • This will be a 3-week trial period to determine feasibility. We will re-evaluate whether this is ongoing after that time. 2 https://www.cognitivemedicinegroup.com
Schedule of Events • July 15 – Neuroanatomy I: Structures • July 22 – Neuroanatomy II: Systems, Pathways, and Tracts • July 29 – Neuroanatomy II: Functions 3 https://www.cognitivemedicinegroup.com
Ground Rules • We kindly request that your camera is turned ON. • Be sure you have clicked “Join Audio” in the lower left corner of your screen. • Please keep your microphone on “Mute” when not speaking. • No recording or sharing of screen shots. • Please do not share the NCTS Zoom link with others. – Any interested trainees should contact Dr. Gooding or Dr. Norman to request access. • Disclaimer: This series is not intended to serve as a replacement or substitute for formal education and training in neuropsychology. 4 https://www.cognitivemedicinegroup.com
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Pic 7 https://www.cognitivemedicinegroup.com
Let’s Get Cellular 8 https://www.cognitivemedicinegroup.com
Gray & White Matter 9 https://www.cognitivemedicinegroup.com
Planes Are Not For Flying • Axial/Transverse/Horizontal •Coronal •Sagittal 11 https://www.cognitivemedicinegroup.com
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How Do I Get There - Directions • Lateral - Medial/Mesial • Inferior - Superior • Rostral - Caudal • Dorsal - Ventral • Posterior - Anterior 13 https://www.cognitivemedicinegroup.com
Head to Tail 14 https://www.cognitivemedicinegroup.com
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Major Division of the Brain 17 https://www.cognitivemedicinegroup.com
Proencephalon (forebrain) • Telencephalon –Cerebral hemispheres •Cortex •Subcortical White Matter •Basal Ganglia •Basal forebrain nuclei 18 https://www.cognitivemedicinegroup.com
Diencephalon • Thalamus • Hypothalamus • Epithalamus 19 https://www.cognitivemedicinegroup.com
Mesencephalon (midbrain) –Cerebral Peduncles –Tectum –Tegmentum 20 https://www.cognitivemedicinegroup.com
Rhombencephalon • Metencephalon –Pons –Cerebellum • Myelencephalon •Medulla 21 https://www.cognitivemedicinegroup.com
Brodmann Areas 22 https://www.cognitivemedicinegroup.com
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Netter Illustration from Netter 24 https://www.cognitivemedicinegroup.com
skull 25 Iimage from Bigler https://www.cognitivemedicinegroup.com
Cranial Nerves 26 https://www.cognitivemedicinegroup.com
Base2 27 https://www.cognitivemedicinegroup.com
Medial 28 https://www.cognitivemedicinegroup.com
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Basal Ganglia • Caudate • Putamen • Globus pallidus • Subthalamic nucleus • Substantia nigra –pars compacta –Pars reticulata • (Nucleus accumbens) • (Ventral pallidum) 31 https://www.cognitivemedicinegroup.com
Lesion in BG •Hyperkinetic (HD) •Hypokinetic (PD) •Mixture 32 https://www.cognitivemedicinegroup.com
Neostriatum or striatum • Caudate + Putamen – Receives all input to BG – Most cortical input is excitatory • (glutamate) – Output is GABA 34 https://www.cognitivemedicinegroup.com
Lentiform • Globus Pallidus + Putamen 36 https://www.cognitivemedicinegroup.com
BG Pic 38 https://www.cognitivemedicinegroup.com
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Brain Stem • 1. Roof Plate • 2. Tegmentum • 3. Basal Portion 40 https://www.cognitivemedicinegroup.com
Axial T2 Image Marc Norman, Ph.D. 42 https://www.cognitivemedicinegroup.com
Axial T2 Image4 Marc Norman, Ph.D. 45 https://www.cognitivemedicinegroup.com
Coronal Marc Norman, Ph.D. 50 https://www.cognitivemedicinegroup.com
Coronal2 Marc Norman, Ph.D. 51 https://www.cognitivemedicinegroup.com
Coronal3 Marc Norman, Ph.D. 52 https://www.cognitivemedicinegroup.com
Homonculus 53 https://www.cognitivemedicinegroup.com
The End is Here • Thanks for joining us! 54 https://www.cognitivemedicinegroup.com
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