Patrick BASTIAENSEN Programme Officer Sub-Regional Representation for Eastern Africa World Organisation for Animal Health Laboratory infrastructure and biological security challenges, from an African perspective
Patrick BASTIAENSEN Jennifer LASLEY Tianna BRAND World Organisation for Animal Health Raphael PRENAT United Nations Security Council Resolution 1540, Group of Experts Laboratory infrastructure and biological security challenges, from an African perspective
Agenda The environment Laboratory performance OIE support to UNSCR 1540 AUC support to UNSCR 1540 Conclusions Source : Pinterest World Organisation for Animal Health · Protecting animals, Preserving our future | 4
Stamping out of bird flu affected poultry farms in Nigeria (2006) Photo credit : public domain (2006) World Organisation for Animal Health · Protecting animals, Preserving our future | 5
Chapter 1 The security challenges and biological threats environment in Africa World Organisation for Animal Health · Protecting animals, Preserving our future | 6
UNSCR 1540 : Why Africa is important Source : se.dreamstime.com World Organisation for Animal Health · Protecting animals, Preserving our future | 7
UNSCR 1540 : Why Africa : human trafficking UNSCR 1540 : Why Africa : drugs trafficking UNSCR 1540 : Why Africa : arms trafficking World Organisation for Animal Health · Protecting animals, Preserving our future | 8
UNSCR 1540 : Why Africa : terrorism Maps kindly supplied by Raphael Prenat World Organisation for Animal Health · Protecting animals, Preserving our future | 9
UNSCR 1540 : Why Africa : health, wildlife World Organisation for Animal Health · Protecting animals, Preserving our future | 10
UNSCR 1540 : Why Africa : terrorism Source : independent.co.uk World Organisation for Animal Health · Protecting animals, Preserving our future | 11
The Nominal Lethality of Different Biological Weapons, Part One World Organisation for Animal Health · Protecting animals, Preserving our future | 12
The Nominal Lethality of Different Biological Weapons, Part One Numbers of casualties from the delivery of 1,000 kg Numbers of casualties from the delivery of 50 kg WHO (1970) OIE Anthrax (Bacillus anthracis) Tularemia (Francisella tularensis) Q fever (Coxiella burnetii) Murine typhus (Rickettsia typhi) Brucellosis (Brucella abortus, melitensis ,…) Tick-borne encephalitis (TBE) Rift Valley fever (RVF) World Organisation for Animal Health · Protecting animals, Preserving our future | 13
The Nominal Lethality of Different Biological Weapons, Part One Numbers of casualties from the delivery of 50 kg WHO (1970) OIE* Anthrax (Bacillus anthracis) Tularemia (Francisella tularensis) Q fever (Coxiella burnetii) Murine typhus (Rickettsia typhi) Brucellosis (Brucella abortus, melitensis ,…) Tick-borne encephalitis (TBE) Rift Valley fever (RVF) (*) Listed diseases in 2017 World Organisation for Animal Health · Protecting animals, Preserving our future | 14
WAHIS (2016) WHO (1970) OIE* 28 Anthrax (Bacillus anthracis) 0 Tularemia (Francisella tularensis) Q fever (Coxiella burnetii) 3 Murine typhus (Rickettsia typhi) 23 Brucellosis (Brucella abortus, melitensis ,…) Tick-borne encephalitis (TBE) Rift Valley fever (RVF) 24 (*) Listed diseases in 2017 World Organisation for Animal Health · Protecting animals, Preserving our future | 15
WHO (1970) Anthrax (Bacillus anthracis) Tularemia (Francisella tularensis) Q fever (Coxiella burnetii) Murine typhus (Rickettsia typhi) Brucellosis (Brucella abortus, melitensis ,…) Tick-borne encephalitis (TBE) Rift Valley fever (RVF) World Organisation for Animal Health · Protecting animals, Preserving our future | 16
WHO (1970) Anthrax (Bacillus anthracis) Tularemia (Francisella tularensis) Q fever (Coxiella burnetii) Murine typhus (Rickettsia typhi) Brucellosis (Brucella abortus, melitensis ,…) Tick-borne encephalitis (TBE) Rift Valley fever (RVF) World Organisation for Animal Health · Protecting animals, Preserving our future | 17
WHO (1970) Anthrax (Bacillus anthracis) Tularemia (Francisella tularensis) Q fever (Coxiella burnetii) Murine typhus (Rickettsia typhi) Brucellosis (Brucella abortus, melitensis ,…) Tick-borne encephalitis (TBE) Rift Valley fever (RVF) World Organisation for Animal Health · Protecting animals, Preserving our future | 18
WHO (1970) Anthrax (Bacillus anthracis) Tularemia (Francisella tularensis) Q fever (Coxiella burnetii) Murine typhus (Rickettsia typhi) Brucellosis (Brucella abortus, melitensis ,…) Tick-borne encephalitis (TBE) Rift Valley fever (RVF) World Organisation for Animal Health · Protecting animals, Preserving our future | 19
WHO (1970) Anthrax (Bacillus anthracis) Tularemia (Francisella tularensis) Q fever (Coxiella burnetii) Murine typhus (Rickettsia typhi) Brucellosis (Brucella abortus, melitensis ,…) Tick-borne encephalitis (TBE) Rift Valley fever (RVF) World Organisation for Animal Health · Protecting animals, Preserving our future | 20
Chapter 2 PVS critical competencies, pertaining to laboratory services and performance World Organisation for Animal Health · Protecting animals, Preserving our future | 21
The OIE PVS Pathway (established 2007) World Organisation for Animal Health · Protecting animals, Preserving our future | 22
(access to) Veterinary laboratory diagnosis CC. II. 1. (A) Revised in 2012 (introducing 1.A and 1.B) The authority and capability of the VS (to have access to laboratory diagnosis in order) to identify and record pathogenic agents, including those relevant for public health, that can adversely affect animals and animal products. Five (5) levels of advancement (LoA) World Organisation for Animal Health · Protecting animals, Preserving our future | 23
(access to) Veterinary laboratory diagnosis CC. II. 1. (A) Level of advancement 1 Level of advancement 2 Level of advancement 3 N = 44 Level of advancement 4 Level of advancement 5 0 5 10 15 20 25 World Organisation for Animal Health · Protecting animals, Preserving our future | 24
Laboratory quality assurance CC. II. 2. Introduced in 2008 The quality of laboratories (that conduct diagnostic testing or analysis for chemical residues, antimicrobial residues, toxins, or tests for, biological efficacy, etc.) as measured by the use of formal QA systems including, but not limited to, participation in relevant proficiency testing programmes. World Organisation for Animal Health · Protecting animals, Preserving our future | 25
Laboratory quality assurance CC. II. 2. Level of advancement 1 Level of advancement 2 Level of advancement 3 N = 30 Level of advancement 4 Level of advancement 5 0 5 10 15 20 25 World Organisation for Animal Health · Protecting animals, Preserving our future | 26
UNSCR 1540 : Why Africa : Ebola crisis World Organisation for Animal Health · Protecting animals, Preserving our future | 27
UNSCR 1540 : Why Africa : Ebola crisis II. 1. (access to) Veterinary laboratory diagnosis “the authority and capability of the VS to have access to laboratory diagnosis in order to identify and record pathogenic agents, including those relevant for public health, that can adversely affect animals and animal products”. World Organisation for Animal Health · Protecting animals, Preserving our future | 28
UNSCR 1540 : Why Africa : Ebola crisis II. 1. (access to) Veterinary laboratory diagnosis 2 / 5 For major zoonoses and diseases of national economic importance, the VS have access to and use a laboratory to obtain a correct diagnosis. > one country World Organisation for Animal Health · Protecting animals, Preserving our future | 29
UNSCR 1540 : Why Africa : Ebola crisis II. 1. (access to) Veterinary laboratory diagnosis 1 / 5 Disease diagnosis is almost always conducted by clinical means only, with no access to and use of a laboratory to obtain a correct diagnosis. > two countries World Organisation for Animal Health · Protecting animals, Preserving our future | 30
Chapter 3 OIE Support World Organisation for Animal Health · Protecting animals, Preserving our future | 31
The OIE PVS Pathway World Organisation for Animal Health · Protecting animals, Preserving our future | 32
PVS Laboratory Support Missions C/Ivoire : Dec. 2015 Sudan : Nov. 2015 Uganda : Oct. 2015 Tunisia : Mar. 2014 Libya : Dec. 2013 Tanzania : May 2013 World Organisation for Animal Health · Protecting animals, Preserving our future | 33
The OIE PVS Pathway World Organisation for Animal Health · Protecting animals, Preserving our future | 34
OIE facilitated lab twinning agreements (29) As per September 2017 Completed : 16 Ongoing : 10 Approved: 3 Worldwide : 82 (Africa 35%) World Organisation for Animal Health · Protecting animals, Preserving our future | 35
OIE facilitated lab twinning agreements (18) OIE listed diseases of the AU-PANVAC List of human and animal Debre-Zeit pathogens and toxins Ethiopia for export control « biosafety and biosecurity » (Australia Group, 2016) Completed : 10 Ongoing : 7 Approved: 1 World Organisation for Animal Health · Protecting animals, Preserving our future | 36
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