Introduction to the BMSS Meetings, Grants, Publications, Networking and more…. Michael Wright & John Dutton Co-ordinators of the Clinical and Forensic Special Interest Group (SIG) of the BMSS
What does the BMSS do? • Non profit organisation run predominantly by volunteer members • Aims are to encourage participation in all aspects of mass spectrometry on the widest basis • Promotion of knowledge and advancement in the field • Provide a forum for the exchange of views and information
The History of the BMSS • 1964 Founded • 1965 1st meeting of the Mass Spectrometry Group (MSG) London 1968 First constitution adopted at 3 rd meeting of the MSG • • 1974 Renamed as the British MS Group (BMSG) • 1980 Became a registered charity on 7th December 1980 • 1981 BMSG is restructured to become the BMSS 1985 Organised 10th IMSC Swansea • • Proceeds led to establishment of 7 Beynon PhD Studentships • 1987 Aston Medal Established (8 awarded to date) • 1993 1st LC-MS Meeting at Cambridge - held every 2 years since • 2002 BMSS President and BMSS Medal established (2 awarded to date) • 2003 Organised 16th IMSC Edinburgh • 2003 John Monaghan becomes first BMSS President 2004 1 st BMSS medal awarded to Ed Houghton 27th Annual Conference, Derby • • 2004 BMSS web-site launched • 2004 Education Initiative launched • 2006 BMSS Sponsored Lecturer Established 2007 Summer studentship programmes launched •
Membership • £30 per year (£10 for students) • Membership entitles you to – Discounted registration for meetings throughout the year – Mass Matters publication – Access to travel grants – Access to equipment grants – Summer studentship grants – Textbook for student members
The Activities of BMSS • Special Interest Groups (SIG) • Annual Meeting • LC-MS Training Course and LC-MS Meeting • One day meetings • Mass Matters • Education in MS • Small equipment grants • BMSS Website • BMSS Awards
How does the BMSS fit in with the NHS? • Historically members were predominantly analytical chemists Academia Forensics Pharmaceutical Industry Government agencies Food Environmental Sports testing Clinical diagnostics is now recognised as the fastest growing sector in MS
Special Interest Groups (SIG) www.bmss.org.uk
Clinical and Forensic SIG Who are we? John Dutton Mike Wright • Bioanalytical Facility, • Department of Biochemistry, Department of Musculoskeletal Biology, Addenbrooke’s Hospital, Cambridge University University of Liverpool Hospital Trust • First tasks – Set up a specific mail-base for Clinical and Forensic users – Prepare a session of speakers at the next annual meeting (Cardiff 2011) – Organise a specific 1 day meeting in collaboration with other clinical and forensic groups
Clinical and Forensic SIG
The Clinical and Forensic SIG mail-base • The BMSS already has a forum for discussion, however, it was felt that a separate mail-base tailored to our SIG was required • The mail-base is open to anyone and not limited to BMSS members • Only restrictions are that the mail-base is not to be used for advertising of products
Topics on the mail-base “Our bone team want to look at low level E2. We presently have TSQ ultra +/- turboflow for such work. Has anyone worked this up with similar set up. Im aware of the application note using the TSQ vantage with LOD of 1pg/ml in BSA, and the comment on poster that this is 10 times better then TSQ ultra (with standard HPLC). Also has anyone gone down the tandem GCMS route?” “We are currently having problems with contamination of our Waters Quattro Micro which we think is due to the solvents we are using, particularly methanol. Injecting methanol results in a number of unidentified peaks and also peaks characteristic of plasticisers. We get similar results with water, however acetonitrile seems fine. We are currently using LC-MS grade ‘Fluka’ methanol and water from Sigma, which we have been advised to use in the past, and have tried new bottles of a different lot number. I was wondering whether anyone else has seen similar problems with this methanol, and whether anyone would recommend methanol and water from a different supplier ?”
The Activities of BMSS • Special Interest Groups (SIG) • Annual Meeting • LC-MS Training Course and LC-MS Meeting • One day meetings • Mass Matters • Education in MS • Small equipment grants • BMSS Website • BMSS Awards
Annual Meeting • 3 day meeting held in September • Covers a wide range of applications and developments in MS in parallel sessions over 3 days • Special Interest Groups often host their own sessions • MS training course • Workshops • Poster sessions • Exhibitions
The BMSS Conference & Exhibition Sunday 5 th to W ednesday 8 th Septem ber 2 0 1 0 • First time away from a university setting • Sessions comprised of: Day 2 Day 1 Plenary Lecture – Alison Ashcroft Maccoll Lecture - Carol Robinson Next Generation Next Generation Separation Science Environmental/Food analysis Manufacturer/Exhibitor Manufacturer/Exhibitor Clinical Analysis Biological Analysis Day 3 Plenary Lecture – John Vickerman Surface/Nano analysis Instrument development Biological Analysis Chair’s invited speaker – Bob Boyd
BMSS 2011: From Atoms to Biomolecules Cardiff city hall 11-14 th September Sunday LC-MS training course Monday - Day 1 Maccoll Lecture -Richard Evershed Next Generation Environmental/Food analysis Manufacturer/Exhibitor Separation Science Tuesday - Day 2 Plenary Lecture – David Muddiman LC-MS training course Next Generation Instrument Developments Manufacturer/Exhibitor Biological Analysis Wednesday - Day 3 Plenary Lecture – Andy Tyler Free Workshop Pathology LIMS interfacing Surface/Nano analysis MS in Clinical Analysis Biological Analysis Chair’s invited speaker – Ron Heeren
BMSS 2011: From Atoms to Biomolecules Cardiff city hall 11-14 th September Will be hosting 2 sessions and 1 workshop on the final day of the meeting (Wednesday 14th September) • First session will include speakers from various clinical and forensic fields • Workshop will look at the difficulties in linking LC-MS/MS and GC-MS systems to hospital LIMS, covering the options and the questions you could ask • Second session will be run in conjunction with the British Endocrine Society with invited speakers from this specialty
Meeting Costs • Registration at www.bmss.org.uk • 3 day meeting – Members £330 (£120 concession) – Non members £380 (£140 concession) • 1day – Members £140 (£50 concession) – Non members £160 (£60 concession)
The Activities of BMSS • Special Interest Groups (SIG) • Annual Meeting • LC-MS Training Course and LC-MS Meeting • One day meetings • Mass Matters • Education in MS • Small equipment grants • BMSS Website • BMSS Awards
LC-MS course and Symposium • A 2 day LC-MS training course & 2 day symposium run every 2 years at Robinson College in Cambridge • Historically attended by analytical chemists from academia, pharma, CRO’s, food industry etc • 2009 saw the first year where a number of NHS staff attended • This years meeting has been compressed into a single day and run twice along-side the Cardiff meeting • Tuesday training course has been tailored to the needs of the clinical market
The Course Tutors Dr Mark Harrison Dr Steve Pleasance, Senior scientist at Managing Director of ThermoFisher Scientific Quotient’s Bioanalytical Sciences business unit. Former Head of World- wide Bioanalysis at GlaxoSmithKline Prof Rainer Cramer FRSC Head of Mass Spec and Proteomics & Prof of Mass Spec and Bioanalytical Sciences, Dr Tony Bristow University of Reading Associate Principal Scientist in mass spectrometry, Dr Jackie Mosely Senior Pharmaceutical Research Officer Mass Development, Spec, Electron Capture AstraZeneca Dissociation, Novel Ionisation Techniques, Chemistry Dept, Durham University
Course fees • Course run on Sunday 11 th September and Tuesday 13 th September • £350 (£200 concessions) • Includes mass spectrometry textbook • People attending the Tuesday course who also wish to attend the meeting will receive £50 off the meeting registration
The Activities of BMSS • Special Interest Groups (SIG) • Annual Meeting • LC-MS Training Course and LC-MS Meeting • One day meetings • Mass Matters • Education in MS • Small equipment grants • BMSS Website • BMSS Awards
The Activities of BMSS • Special Interest Groups (SIG) • Annual Meeting • LC-MS Training Course and LC-MS Meeting • One day meetings • Mass Matters • Education in MS • Small equipment grants • BMSS Website • BMSS Awards
The BMSS Education Initiative • Education of the membership of BMSS is a key role of the society • Student Travel Grants – The initiative funds travel grants to allow student members to attend UK based and international mass spectrometry meetings. • The initiative funds a free mass spectrometry textbook for all new student members of BMSS
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