What were neurons invented for? 2 1 1/25/17 To move things is all - PDF document

Jun 27, 2023 •39 likes •149 views

1/25/17 What were neurons invented for? 2 1 1/25/17 To move things is all that mankind can do...for such the sole executant is muscle, whether in whispering a syllable or in felling a forest. Charles Sherrington 1924 3

1/25/17 What were neurons invented for? 2 1
1/25/17 “To move things is all that mankind can do...for such the sole executant is muscle, whether in whispering a syllable or in felling a forest.” Charles Sherrington 1924 3 “Sensorimotor Brain system” Sensors Muscles 4 2
1/25/17 Lab 1: Neurons and the Brain (and Matlab) Neuroscience primer: Brain & neuron Membrane potential Action potential Synaptic transmission • Lab part 1: Neurons in Matlab • Lab part 2: Brain in 3D Online 3
1/25/17 ACTING! SENSING The Brain motor cortex (voluntary movement) prefrontal cortex visual (planning; cortex working memory) cerebellum brainstem (movement coordination (involuntary, movement learning) reflexive behaviors) • Approximately 10 11 neurons in a human brain • Approximately 10 15 synapses connecting them 4
1/25/17 Neurons and synapses (~10 -3 mm) 10 μm Lab 1: Neurons and the Brain (and Matlab) Neuroscience primer: Brain & neuron Membrane potential Action potential Synaptic transmission • Lab part 1: Neurons in Matlab • Lab part 2: Brain in 3D Online 5
1/25/17 Neurons send fast long-distance signals Membrane potential: charge imbalance 6
1/25/17 The electrical properties of neurons are what enables them to regulate every aspect of behavior. - + -65 mV Membrane potential aka membrane voltage is the difference between the electric potential outside vs inside the cell: Vm = Vin – Vout 7
1/25/17 Adding plus charge (positive current ) inside the cell makes the inside less negative compared to the outside 16 http://howmed.net/physiology/action-potential/ 8
1/25/17 Spikes! Firing rate = (number of spikes)/(time) Excitation: higher firing rate Inhibition: lower firing rate and membrane is hyperpolarized Propagation 18 http://www.rci.rutgers.edu/~uzwiak/AnatPhys/APFallLect18.html 9
1/25/17 Lab 1: Neurons and the Brain (and Matlab) Neuroscience primer: Brain & neuron Membrane potential Action potential Synaptic transmission • Lab part 1: Neurons in Matlab • Lab part 2: Brain in 3D Online Neuron-to-neuron Synapse 10
1/25/17 21 11

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