The DiaGene: a prospective case-control study Sunny Singh Badal MD, PHD student Department: Vascular Medicine
Type 2 Diabetes Mellitus (T2DM) RIVM: Rising prevalence and incidence Prevalence 2017: 1135100 Incidence 2017: 60200 Still high percentage develop complications
Methods DiaGene study - Multicenter prospective case-control study - DM2 cases, healthy controls - Eindhoven: Maxima Medisch Centrum, Catharina Hospital, Diagnostic Center Eindhoven (General practioners) Van Herpt, Thijs T. W. et al. “Introduction of the DiaGene Study: Clinical Characteristics, Pathophysiology and Determinants of Vascular Complications of Type 2 Diabetes.” Diabetology & Metabolic Syndrome 9 (2017): 47. PMC . Web. 16 July 2017
Methods DM , diabetes mellitus; MODY, Maturity-Onset Diabetes of the Young; Latent Auto-immune Diabetes of the Adult
Statistics Endpoints Macrovascular complications: Ischemic brain disease, ischemic heart disease. PAD etc. Microvascular complications Retinopathy, nephropathy, neuropathy, composite endpoint Genetic associations with incident and prevalent complications will be assessed
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