Myra Dioquino Ne Neuron Ne Neuron ons ons ~30x out ~30x in - PowerPoint PPT Presentation

Oct 21, 2023 •358 likes •455 views

Myra Dioquino Ne Neuron Ne Neuron ons ons ~30x out ~30x in 20 000 20,000x out o t ~30x out Describes the equilibrium potential of the cell for a particular ion R Universal gas constant (8.314472 J K ) T

Myra Dioquino
Ne Neuron Ne Neuron ons ons ~30x out ~30x in 20 000 20,000x out o t ~30x out
Describes the equilibrium potential of the cell for a particular ion
� R Universal gas constant (8.314472 J • K ⁻ ¹) � T Absolute temperature (Temp. °C + 273.15 K) � z � z Ionic charge (+1 for K ) Ionic charge (+1 for K ⁺ ) � F Faraday constant (9.6485309 x 10 ⁴ C mol ⁻ ¹) ² ²
Nernst Equation Simulator: www.nernstgoldman.physiology.arizona.edu
� Ions flow across membrane according to gradient “Chemical concentration vs. electrical potential” potential � An ion continues to flow until the equilibrium potential for that ion has been reached potential for that ion has been reached � Each ion contributes to net current � Each ion contributes proportionally to its rate p p y of conductance “Selective permeability”
� Why we need them: Lipid bilayer itself doesn’t allow ion leakage across membrane
Figures/images courtesy Dr. Saxena & Dr. Draper

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