Final Draft Advancing Advancing a a Master Plan Master Plan for B for Biosciences iosciences Development Development in Los in Los Angeles Angeles County County Di Disc scuss ussion ion of Fina of Final l Dr Draft Ma aft Master ster Plan Plan w wit ith h Upda Updated ted Ind Industry ustry an and d Ventu Venture re Capital T Capital Tren rends ds Battelle Technology Partnership Practice October 2014 BUSINESS SENSITIVE 1
Final Draft Today’s Discussion • Recap Project Purpose & Approach • Key Findings from Feasibility Assessment • Overview of Strategic Priorities & Actions • Detailed Discussion of Actions – Key Features – Priority – Resources • Implementation Approach BUSINESS SENSITIVE 2
Final Draft A Word on Battelle’s Technology Partnership Practice Battelle TPP is the economic development consulting arm of the world’s largest independent, non -profit research and development organization. Battelle TPP is nationally recognized for its thought leadership in biosciences development and hands-on experience in states and regions across the nation • Bioscience Strategies • National Reports – States of Arizona, – BIO State Bioscience Colorado, Georgia, Industry Report, 2002- Iowa, Maryland, 2012 reports Michigan, Missouri, – Biopharmaceutical Nebraska, Utah, International Report for Mississippi PhRMA, 2012 – Regions: Central – Impact of Human Genome Indiana, Central Ohio, Project, 2011 Flagstaff, Memphis, – Council for American Peoria, Oklahoma City, Pittsburgh, St. Louis, Medical Innovation Tucson National Agenda, 2010 BUSINESS SENSITIVE 3
Final Draft Project Purpose & Approach • PURPOSE: Develop a fact-based, comprehensive bioscience industry cluster development strategy to enable Los Angeles County to realize its full potential as a bioscience hub. BUSINESS SENSITIVE 4
Final Draft Developing A Bioscience Industry Clusters Req equir uires es Attent Atte ntion ion to to E Ever ery y Link Link i in n th the De e Develop elopmen ment t Cha Chain in Business Attraction Links in the Economic Development Chain Existing Biotech Basic Applied Piloting & Technology New Enterprise Business Industry Cluster Science R&D Demonstration Transfer Development Expansion Talent Faculty, Post-Docs, Graduate Students, STEM graduates Entrepreneurs, Professional Services, Line/Production Workers Ingredients for building a critical mass in the biosciences in states and regions include: Engaged universities with active leadership Building entrepreneurial cultures with intensive networking across sectors and with industry Available capital covering all stages of business cycle Discretionary federal or other R&D funding Workforce and talent pool Access to specialized facilities and equipment Supportive business, tax and regulatory policies Patience and a long-term perspective BUSINESS SENSITIVE 5
Final Draft Key Findings LOCATION: COMPETITIVENESS: RECENT TRENDS: Broad footprint with Despite promise, off Strong Growth and limited clustering pace of leading regions Promise of Biosciences for LAC • Widely distributed • Generally positive • Biosciences industry footprint … No trends for LAC, but lag emerging as key “Hollywood” for leading regions in: economic driver Biosciences in LAC – Industry growth – Gaining Competitive • Immature bioscience real Share – Research growth estate market , with few if – Key Local Economic – Venture capital any specialized facilities Driver : – Specialization of skills • Lack of continuum of – Sizable Base space beyond modest • Depth of research & – Presence of incubators reflects lack of innovation base offers commercial footing in LA several key technology bioscience space platforms for growth • But lack of venture financing creating a “leaky bucket” for LAC capturing innovation BUSINESS SENSITIVE 6
Final Draft Where BioEconomy Stands Today: A Leading Economic Driver for LAC LA County Bioscience Industry Employment Trends Source: Battelle analysis of Bureau of Labor Statistics, QCEW data; enhanced file from IMPLAN. BUSINESS SENSITIVE 7 7
Final Draft Though not performing as well as the nation LA County & U.S. Bioscience Industry Employment Trends, 2007-12 Source: Battelle analysis of Bureau of Labor Statistics, QCEW data; enhanced file from IMPLAN. BUSINESS SENSITIVE 8 8
Final Draft Composition of the Nonhospital Biosciences by Region — LA Relatively Diverse Employment Composition of the Nonhospital Biosciences, 2010 66K 55K 14K 42K 40K 33K 26K 25K 100% 90% 34% 37% 38% 80% 41% 42% 50% 50% 70% 67% 60% 12% 11% 26% 50% 21% 33% 18% 40% 30% 24% 37% 5% 30% 16% 16% 31% 4% 15% 20% 13% 23% 21% 20% 10% 15% 13% 13% 13% 7% 0% 0% 0% 1% 0% 0% 0% 0% 0% Boston Philadelphia Los Angeles San Francisco San Diego Washington, Research Pittsburgh County DC Triangle, NC Ag Feedstock & Chemicals Bioscience-related Distribution Drugs & Pharmaceuticals Medical Devices & Equip Research, Testing, & Medical Labs BUSINESS SENSITIVE Source: Battelle analysis of Bureau of Labor Statistics, QCEW data; enhanced file from IMPLAN. 9
Final Draft Industry Landscape - Composite Company Key BioTech R&D Drugs & Pharma Med Devices Med Labs Institutional Key County Medical Centers Research Institutions BUSINESS SENSITIVE 10
Final Draft In Biosciences-related Academic R&D, LA County among Top Tier of Benchmarks Academic R&D Expenditures in Bioscience-related Fields, 2010 Research Triangle $1,642 San Francisco $1,135 LA County $1,128 Boston $1,003 San Diego $996 Philadelphia $980 Pittsburgh $737 Washington, DC $389 $- $200 $400 $600 $800 $1,000 $1,200 $1,400 $1,600 $1,800 Millions of Dollars Source: NSF Survey of R&D Expenditures at Universities and Colleges. BUSINESS SENSITIVE 11
Final Draft Line of Sight to Possible Technology Platforms Leading Biosciences Core Competency Areas Likely Biosciences Industry Products Technology Platforms – Primarily Applications and Services - Musculoskeletal Research and Implant Devices Current Strengths - Biologics for Therapeutics and Electro-Medical Devices Diagnostics Surgical Appliances & - Electro-Medical Devices Novel Therapeutics & Supplies - Surgical Instruments & Devices Diagnostics Medical Labs - Biomedical Imaging - Dental Materials, Implants and Devices Emerging Strengths - Public Health & Healthcare Management Biotech Commercial R&D - Health Informatics Pharmaceutical Mfg – Primarily Disease Areas Bioengineering Solutions Surgical & Medical - Cancer Instruments for Treating Diseases and - Psychological Disorders & Human Hospitals Medical Conditions Behavior Drug Distribution - Neurodegenerative/Neurological Diseases Testing Labs - Infectious Diseases Biological Products - Cardiovascular Innovations in Healthcare In Vitro Diagnostics - Ophthalmology Delivery Specialized Industries - Inflammatory Diseases Medicinal/Botanical Mfg - Transplantation - Nephrology & Urological Diseases Dental Equip & Supplies - Respiratory Disorders - Drug Development & Delivery – Primarily Basic Biological Sciences - Genetics & Genomics - Protein Sciences - Metabolic Biology - Stem Cell Biology BUSINESS SENSITIVE 12
Final Draft What Distinguishes LA County in Specific Growing Markets for Preliminary Technology Platforms Bioengineering Solutions Innovations in Healthcare Novel Therapeutics & for Treating Diseases and Delivery Diagnostics Medical Conditions • Key focus on biologics both for • LA County unusual in • LA County research institutions therapeutics and diagnostics – having industry stand out in health care seeing recent growth in strengths across sciences and policy. industry in these areas as well. electro-medical, • Well over 10 NIH funded musculoskeletal and • Emergence of stem cell research centers focused on surgical devices as well research for advancing quality of care, health as biomedical imaging + therapies and delivery promotion, health disparities specialization in dental mechanisms and community participatory materials & devices. research. • Also draws on strengths in • Seems very device • Emergence of base of Protein Sciences and oriented … plays to Genetics/Genomics found in innovative health services and strengths in engineering LA research institutions. health informatics companies. found in universities. • Cancer is leading area of • Clinical excellence seen via PI- – Application of development from PI-initiated initiated clinical trials 9 microelectronic drug/biologics trials – but other hospitals with nationally ranked systems and active areas include: specialties, extensive GME nanotechnology key programs but hospital base Psychiatric Disorders, Cardiovascular, low in concentration and lagging growth BUSINESS SENSITIVE 13
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