IberoAmerican Pharmacogenetics Network Red Iberoamericana de Farmacogenética Enrique Terán MD PhD On behalf of the RIBEF researchers team
Jose María “Chema” Cantú (+) Mexican pioneer in Genetics Human Genome Project LA Leader
TOXICITY Slow Metabolizers LACK EFFICACY Ultrarapid Metabolizers
Interethnical variability: CYP2D6 gene multiplication (Ultrarapids?) Interethnic distribution of individuals with CYP 2D6 gene duplicated
Adrián LLerena 2016 allerena@unex.es
RIBEF Activities 2006-2014 Activity Number Countries involved Diffusion of information 322 31 Capacitation of Human 101 12 resources Production of Scientific 22 13 information Guidance to Clinical 1 02 implementation Total 446 31
Diffusion activities per year
CEI CEIBA A Con onsor sorcio cio Eur urop opeo eo Ib Iber ero o Amer merican icano o Far armac macog ogen enét ética ica Population Pharmacogenetics among Iberoamerican populations N= 6050
African Admixed Ashkenazi Native Caucasians 6050 Americans Americans Jews Americans Volunteers 1384 1824 96 2571 174 CEIBA Consortium POR CUB 2016 MEX NIC SPA CRI n=426 COL n=98 ECU n=294 n=452 n=713 BRA n=528 PER n=1550 n=133 n=286 URU n=32 CHI n=1081 n=456 ARG
MESTIFAR: Relationship with ancestry (declare/molecular markers) ARG PER MEX MEX PER
IBEROFEN 17IA004 GENES AND METABOLIC PHENOTYPES IN AMERICAN POPULATION Interaction genes-environment on the metabolic phenotype in autochthonous and admixed populations in Iberoamerica
Pasantías =81 HR exchange =86
Training = 343 activities
Publications =51
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