HPV Vaccination for Cancer Prevention Pamela C. Hull, Ph.D. Rural Healthcare Providers Symposium February 27, 2020
Collaborators and Partners Meharry-Vanderbilt-TSU Cancer Partnership Vanderbilt University Medical Center Meharry Medical College Debra Friedman, MD Maureen Sanderson, PhD Stephen Deppen, PhD Tennessee State University Tatsuki Koyama, PhD Elizabeth Williams, PhD Liping Du, PhD Cumberland Pediatric Foundation Caree McAfee, MA, CHES Lora Harnack, MSN Jaimie Shing, MA Janet Cates Jessica Jones, MS Christine Stroebel, MPH Kelsey Minix, MPH Community Partners Alyssa Rentuza MVTCP Community Advisory Board Juan Canedo, DHSc HPV Cancer Free Tennessee Coalition Vanderbilt University TN Department of Health Shelagh Mulvaney, PhD Progreso Community Center Supported by NIH grant numbers: R01CA207401, U54CA163072, U54CA163066, U54CA163069, 3P30CA068485-18S3, UL1 RR024975, UL1 TR000445, and VU Trans-Institutional Programs
Infections cause some cancers Hepatitis C virus HPV (human Hepatitis B virus papillomavirus) Helicobacter pylori Courtesy of Krystle Kuhs, PhD
% Attributed to HPV HPV causes a large 75% burden of cancers, 63% pre-cancers, and genital warts 69% 91% 91% 70% Data from Viens et al. MMWR 2016. https://www.cdc.gov/cancer/hpv/statistics
Epidemic of HPV Oropharyngeal Cancer Oropharynx (Overall) 10 HPV-positive Oropharynx HPV-negative Oropharynx Rates per 100,000 225% Increase HPV 1 Tobacco & Alcohol Oropharynx Calendar Years Chaturvedi et al, J Clin Onc, 2011 Gillison Vaccine 2012; headandneckcancerguide.org Courtesy of Krystle Kuhs, PhD
1 new case of HPV-related cancer every 20 minutes
Screening is only available for cervical cancer
Routine HPV vaccination recommended for both males and females at ages 11 – 12 years *Late: 13-26 years 6-12 months after 1 st dose 2 & 6 months after 1 st dose MMWR 2016;65(49) 1405-1408 http://dx.doi.org/10.15585/mmwr.mm6549a5
Human Papilloma Virus (HPV) Vaccination Tennessee, 2018 100% Healthy People 2020 Goal: 80% Series Completion 90% 80% * Significantly lower than Urban at p<0.05 70% 70% 59% * 60% 48% 50% 45% * 45% 40% 31% * 30% 20% 10% 0% 1+ Dose All Doses Urban Suburban Rural/Town Source: 2018 NIS-Teen Data
HPV Vaccination: Challenges
Baseline Follow Up Results 2.5-fold increase in providers using evidence-based “announcement” communication 17% increase in HPV vaccination 30% Increase in Bundling HPV Vaccine during well visits with Other Adolescent Vaccines
Available Materials: Co-brand with your logo SPANISH TN Dept of Health: Video Print ads Social media Front & Back of Clinic Flyer (space for logo) Bus wraps Magnet Billboard https://www.youtube.com/watch?v=PfgS31AfGvs Request: TIP.Quality@tn.gov Request: get3shots.org
https://tinyurl.com/smbhbo5 Kristina.G.Bradford@tn.gov www.hpvcancerfree.org immunizetn@gmail.com Rochelle.Roberts@tn.gov
Supplemental Slide for Q&A
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