Palliative & End of Life Care Services N E Lincs House Keeping Syringe Driver Training: McKinley T34 Pump Fire alarm and toilet facilities Willingness to participate Embrace a supportive and safe learning environment Confidentiality - discussions stay in the room Non personal Listen and respect Mobile phones Keep to time Evaluation Form Palliative & End of Life Care Services N E Lincs Palliative & End of Life Care Services N E Lincs 1 1 Palliative & End of Life Care Services N E Lincs 2 Professional Responsibility And Aims Of The Training Accountability The registered nurses/practitioners' responsibility and The Code (NMC,2015) sets out the core standards of accountability. conduct and practice expected of nurses and midwives, it Indications for use is a positive tool to use that reflects contemporary Support of both patient and family nursing and midwifery practice and plays a key role in the Common drugs used in the syringe driver for palliative and end of revalidation process life patients Converting drugs from oral medication to the subcutaneous route Pre-operational inspection of the machine • Prioritise people Demonstration of safe and effective preparation and management • Practice effectively of the syringe driver • Preserve safety Knowledge of the appropriate policy for Procedure for the use of • Promote professionalism and trust the McKinley Syringe Pump in Palliative and End of Life Care Be aware of other regulatory bodies Palliative & End of Life Care Services N E Lincs 3 Palliative & End of Life Care Services N E Lincs 4 Indications For Using The Preserve Safety Syringe Driver Unable to take oral medications Swallowing problems 18. Advise on, prescribe, supply, dispense or Uncontrolled nausea and/or vomiting Intestinal obstruction administer medicines within the limits of your Profound weakness in last days of life training and competence.... Malabsorption 19. Be aware of, and reduce as far as possible, Contra-indications Pain which has not been controlled by oral analgesia any potential for harm associated with your Special care to be taken with very restless patients practice…. Palliative & End of Life Care Services N E Lincs 5 Palliative & End of Life Care Services N E Lincs 6 12/06/2019 1
Palliative & End of Life Care Services N E Lincs Sites That Should Not Be Used For Subcutaneous Infusion Sites Cannula Placements Are: Anterior Anterior Aspect Chest Wall Of Upper Arm Lymphoedematous limbs Sites over a bony prominence Anterior Abdominal Previously irradiated skin area Wall Broken skin Anterior Aspect Sites near a joint Discuss with patient their preferred Of Thighs place to site infusion Localised areas of disease Visually inspect at each time patient Affected limb following lymph node reviewed dissection Palliative & End of Life Care Services N E Lincs 7 Palliative & End of Life Care Services N E Lincs 8 Diamorphine Communication Indications for use: pain control & breathlessness Explain to the patient and relatives: Caution in renal failure Used because of its high solubility: 1g dissolves in 1.6mls of water What a syringe driver is No clinical advantage over Morphine How it works No maximum dose No contra-indications if titrated carefully against Why the team have chosen to use it a patient's pain Allow time for questions Onset of action 5-10 mins SC, duration of action 4hrs Use water or 0.9% sodium chloride as diluent Palliative & End of Life Care Services N E Lincs 9 Palliative & End of Life Care Services N E Lincs 10 Converting Oral Morphine To Managing Diamorphine Shortage Subcutaneous Diamorphine As an alternative, prescribe Morphine Sulphate Add together oral analgesia (Not PRN doses) in injection (10/15/20/30mg/ml) milligrams/24 hours Divide total dose by 3 Morphine Sulphate is compatible with the This is the required 24 hour dose of Diamorphine via commonly used drugs in a syringe pump e.g. subcutaneous infusion Haloperidol, Levomepromazine, Hyoscine Divide the total 24 hour dose of S/C Diamorphine by Butylbromide, Metoclopramide, Glycopyrronium and 6 to give the required dose of S/C breakthrough/prn Midazolam medication Holistic assessment of patient Seek specialist advice re conversions etc. Palliative & End of Life Care Services N E Lincs 11 Palliative & End of Life Care Services N E Lincs 12 12/06/2019 2
Palliative & End of Life Care Services N E Lincs Oxycodone Converting Oxycodone Oral Oxycodone to SC Oxycodone divide by 2 Similar properties to Morphine, acts on different pain receptors. 20mgs Oral Oxycodone = 10mgs s/c Oxycodone Morphine is always the first drug of choice Useful for patients who cannot tolerate Oral Morphine to Oral Oxycodone divide by 2 Morphine. Appears to cause less sedation and vomiting than Morphine but more constipation. 20mgs oral morphine = 10mgs oral oxycodone Used for patients with renal impairment Diluent Water for injection or 0.9% Sodium Note: injection solution is called Oxycodone Chloride Hydrochloride solution for injection or OxyNorm Caution when mixing with subcutaneous injection Cyclizine Palliative & End of Life Care Services N E Lincs 13 Palliative & End of Life Care Services N E Lincs 14 PRNs Transdermal Fentanyl Strong opioid licensed for severe chronic Why given? (persistent, long-term) pain Dose? It is not licensed for uncontrolled or acute pain. Effective? Available in 12mcg, 25mcg, 50mcg, 75mcg and 100mcg in 72hrs Duration? Pain unrelieved by Morphine will not be Pattern? relieved by Fentanyl Steady-state plasma concentration generally Acute events? achieved by 36-48hrs, but sometimes only Over the counter? achieved after 9-12 days Small percentage of patients require patch Holistic assessment! change every 2 days (Always seek specialist advice in this situation) Palliative & End of Life Care Services N E Lincs 15 Palliative & End of Life Care Services N E Lincs 16 Transdermal Fentanyl Chart Transdermal Fentanyl 4 hourly oral Morphine (mg) Transdermal Fentanyl Patch 24 Hourly Oral Morphine (mg) Strength (mcg/hr) Indications for use <20 25 <135 Difficulty swallowing tablets/tablet 25 – 35 50 135 – 224 phobia/compliance 40 – 50 75 225 – 314 Intolerable effects with Morphine e.g. 55 – 65 100 315 – 404 nausea/vomiting/hallucinations/constipation 70 – 80 125 405 – 494 Renal impairment 85 – 95 150 495 – 584 100 – 110 175 585 – 674 High risk of tablet misuse 115 – 125 200 675 – 764 130 – 140 225 765 – 854 The Fentanyl patch should continue to be changed 145 – 155 250 855 – 944 as prescribed and will control the 160 – 170 275 945 - 1034 background/chronic pain 175 – 185 300 1035 - 1124 Palliative & End of Life Care Services N E Lincs 17 Palliative & End of Life Care Services N E Lincs 18 12/06/2019 3
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