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CAREX&Canada&*&Suppor0ng&the&Priori0za0on&of& Primary&Preven0on&Programs& & Paul&A.&Demers ! Scien'fic!Director,!CAREX!Canada! Director,!Occupa'onal!Cancer!Research!Centre! ! The!CAREX!Canada!Team!is!based!at:! School!of!Popula'on!and!Public!Health,!University!of! Bri'sh!Columbia! Spa'al!Sciences!Research!Lab,!University!of!Victoria! 1

What we know about occupational and environmental carcinogens? Based on the International Agency for Research on Cancer there are: • ~ 60 definite or probable carcinogens • Over 100 additional exposures are possible carcinogens • Many other exposures with a suspicion of human carcinogenicity

Basic Questions Remain • How many people are exposed to workplace and environmental carcinogens? • How and where are they exposed? - What are the sources of exposure? - What types of workplaces? - Which communities? • How high are their exposures?

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CAREX Canada • Pilot studies begin in 2003 • Fully funded by CPAC in 2008 (renewed 2012) • Differs from original CAREX – Environmental estimates – Much more detailed estimates – Level of exposure where possible 5

CAREX Canada: General Approach Generate estimates of the number of people exposed and levels of exposure using: – Existing Canadian exposure data – Census population data – The best exposure estimation procedures available. 6

CAREX Canada Occupational Projects Are exposures How many are above exposed to regulatory hazardous levels? limits? What has been How many measured in Where do people are How do Canada? these exposed? provinces exposures compare? occur? Canadian Workplace OCCUPATIONAL Exposure Database ESTIMATES In what Where are What are the industries and In what industries women trends over occupations do hazardous exposed? time? are the highest exposures occur? exposures? 7

CAREX Canada Environmental Projects Are levels higher What are the outdoors, indoors, sources of in drinking water or pollution? in food? How much What are pollution is typical levels of What is the Where emitted? pollution? estimated excess are the cancer risk for sources these levels? located? EMISSIONS MAPPING EXCESS RISK PROJECT PROJECT (eRISK) How do the Tell me more How does Tell me more emissions in about this estimated excess about this this area pollutant cancer risk pollutant compare to compare across other areas? pollutants? 8

Potential Uses of Hazard Surveillance: Primary Prevention • Target high risk groups • Set priorities for prevention-related activities • Monitor trends • Assess the impact of regulations • Predict future cases of disease • Provide exposure data for epidemiology • Educate the public and policy makers