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An Introduction to May 2013 Table of Contents I. Executive Summary II. The Value Void III. The Healthios Exchange (H/X) Appendices IV. H/X Case Studies & Empirical Track Record Research. Investment Banking. Healthcare. Diabetic

  1. An Introduction to May 2013

  2. Table of Contents I. Executive Summary II. The Value Void III. The Healthios Exchange (“H/X”) Appendices IV. H/X Case Studies & Empirical Track Record Research. Investment Banking. Healthcare.

  3. Diabetic Nephropathy Cardiovascular Devices Diabetic Retinopathy Prosthetic Heart Valve Hypercholesterolemia Peripheral Vascular Devices Oral Mucositis Cardiovascular Monitoring & Diagnostic Devices Gout Cardiovascular Surgery Acute Lymphocytic Leukemia Cardiac Rhythm Management Bone Metastasis Cardiovascular Prosthetic Devices Brain Cancer Interventional Cardiology Breast Cancer Cardiac Assist Devices Cervical Cancer Wound Care Management Chronic Lymphocytic Leukemia Hospital Supplies Endometrial Cancer Syringes and Needles Ewing Sarcoma Disposable Hospital & Surgical Supplies Gastric Cancer Drug Delivery Devices Gastrointestinal Stromal Tumors Inhalation Systems Head And Neck Cancer Needle Free Injections Hodgkin Lymphoma Infusion Systems Kidney Cancer Diabetes Care Devices Liver Cancer Insulin Delivery & Glucose Monitoring Malignant Mesothelioma Ophthalmic Devices Medullary Thyroid Cancer Cataract Surgery Devices Melanoma Ophthalmic Diagnostic Equipment Multiple Myeloma Refractive Surgery Devices Non-Hodgkin Lymphoma ENT Devices Non-Small Cell Lung Cancer Hearing Implants Ovarian Cancer Diagnostic Devices Pancreatic Cancer Electrosurgical Devices Testicular Cancer Dental Equipment & Accessories Thyroid Cancer Diagnostic Imaging & MRI Systems Age Related Macular Degeneration C/T Systems & Mammography Equipment Keratoconjunctivitis sicca (Dry Eye) X-Ray & Ultrasound Systems Retinal Vein Occlusion Nuclear Imaging Equipment Acute Respiratory Distress Contrast Media Injectors Executive Summary Syndrome Bone Densitometry Sepsis Anesthesia and Respiratory Devices Staphylococcal Infections Anesthesia Machines & Disposables Acute Coronary Syndrome Respiratory Devices & Disposables Angina Pectoris Sleep Apnea Diagnostic Systems Atrial Fibrillation Healthcare IT Coronary Artery Disease (CAD) Medical Imaging Information Systems Critical Limb Ischemia Nephrology and Urology Devices Hypertension Renal Dialysis Equipment Pulmonary Arterial Hypertension Orthopedic Devices Acute Pain Orthobiologics & Arthroscopy Anxiety Disorders Joint Reconstruction Chronic Pain Trauma Fixation Dementia Orthopedic Prosthetics Diabetic Neuropathy Cranium Maxillofacial Fixation (CMF) Obsessive-Compulsive Disorder Spinal Surgery Osteoarthritis Pain Endoscopy Devices & instruments Parkinson's Disease Rigid & Flexible Endoscope Post-Traumatic Stress Disorder In Vitro Diagnostics Restless Legs Syndrome Genetic Testing Schizophrenia Clinical Chemistry Traumatic Brain Injury Hematology Liver Cirrhosis Immuno Chemistry Childhood Enuresis Infectious Immunology Growth Hormone Disorders Histology And Cytology Hyperparathyroidism Patient Monitoring Hyperthyroidism Multiparameter Patient Monitoring Guillain-Barre Syndrome Micro-Electromechanical Systems Cytomegalovirus Non-invasive Blood Pressure Monitors Fungal Infections Neurology Devices Gram-Negative Bacterial Infections Neurostimulation Devices H1N1 Infection Interventional Neurology Herpes Zoster CSF Management HIV-1 Infection Neurosurgical Products Human Papillomavirus Infections Radiosurgery Staphylococcus Aureus (MRSA)

  4. Healthios Overview of the Firm I n v e s t m e n t B a n k i n g G l o b a l I n v e s t m e n t M a r k e t p l a c e Healthios is a boutique investment bank focused exclusively on the global healthcare industry. Healthios seeks to be the premier investment bank serving the global healthcare industry by combining the experience of (52) transactions in 17 countries with transformational capital markets solutions which broaden access to financing, lessen risk and maximize value. Research. Investment Banking. Healthcare.

  5. Executive Summary In 2013, the 2 nd generation of Healthios Exchange (“H/X”) will seek to transform the healthcare capital markets. Inspired by extraordinary economic and regulatory paradigms, the H/X will combine revolutionary technology with direct access to the individual healthcare investor, worldwide. In the process, H/X will generate $5 of NEW growth capital to support every $1 of institutional and strategic commitment. � Opportunity Healthcare is the largest, fastest growing and most dynamic market in the world � Superior investment returns driven by favorable global demographics, universal need, persistent innovation and rapid, sustained growth � Problem Value Void: “Gap” in global healthcare capital flows alters the risk/reward equilibrium and provides transformational investment opportunities � Context 2012 JOBS Law establishes new structural paradigm for capital markets � Private Capital phenomenon & direct listing framework are catalyst for new capital formation model � Solution www.healthios.com / hx : End-to-end, cost effective, capital efficient, high- velocity, standardized, transparent and secure transaction platform � Financing the healthcare industry in the manner in which it capitalizes itself � Database of 100,000 accredited investors, worldwide � Proprietary asset classes designed to complement institutional, strategic capital � TM , Foundation Place TM , EX.PR.E.S.S. TM , InMarket TM , LiquidNET TM CrowdFinance Research. Investment Banking. Healthcare.

  6. Global Healthcare Investment Environment In total, healthcare is the world’s fastest growing industry. It generates superior investment yields. It attracts capital more readily and regularly. RELATIVE RETURN: S&P HCX vs. S&P ABSOLUTE RETURN: NBI vs. S&P 600% 100% 80% 500% 60% 400% 40% 20% 300% 0% 200% -20% -40% 100% -60% 0% -80% -100% -100% TOTAL RETURN: NBI vs. HCX vs. S&P 400 Biotech vs. NASDAQ Healthcare Index vs. S&P 500 250% 200% 150% 100% 50% 0% -50% -100% Research. Investment Banking. Healthcare.

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