ADAPTABLE: Stakeholder Perspective Kevin Haynes, PharmD, MSCE - PowerPoint PPT Presentation

ADAPTABLE: Stakeholder Perspective Kevin Haynes, PharmD, MSCE Principal Scientist @khaynes001 9/20/2019

Kevin Haynes, PharmD, MSCE • Has nothing to disclose. 2

PCORnet in Action • Stakeholder Perspective: Health Plan Research Network • HealthCore-Anthem Research Network • Real-world evidence for aspirin therapy: ADAPTABLE • Provider engagement • Patient/member engagement • Longitudinal outcome capture 3

Anthem: A Health Benefits Leader 1 in 8 Americans 40+ million over 78 million total medical total lives served members in affiliated health plans Q2 2019 Data Anthem Blue States (14): California, Colorado, Connecticut, Georgia, Indiana, Kentucky, SUBSIDIARIES Maine, Missouri, Nevada, New Hampshire, New York, Ohio, Virginia, Wisconsin 4

HIRE  HealthCore Integrated Research Environment Information on 66+ million individuals representing 1 in 8 Americans from multiple health plans across the U.S. 48+ million private U.S. commercial lives with medical and pharmacy claims, spanning 14 states from health plans dating back to 2006 Lab results for 17+ million lives integrated with claims data Clinical Oncology data COMPANY CONFIDENTIAL | DO NOT COPY 5

Data Integration Via Direct Linkage 6

Health Plans and ADAPTABLE Millions of members take aspirin for secondary coronary prevention Tens of thousands of providers manage health plan members Desire to communicate evidence based medicine to our providers and membership Professional desire to assist in closing gaps in evidence through stakeholder engagement 7

ADAPTABLE Provider Engagement 8

Health Plan Member ADAPTABLE Recruitment 9 9

Incidence Rates of Outcome Events from Single Network Partners, Single CDRNs, PCORnet CDRNs and HCARN Respectively 884,311 11,101 HCARN members identified overlapped with PCORnet as ADAPTABLE eligible CDRN network partners Occurred outside CDRNs Hospitalized for ASCVD 1,521 571 37.5% Hospitalized for major bleeding 710 296 41.7% Deaths at hospital 196 67 34.2% Clin Trials. 2019 May 13 10

Learn More • www.pcori.org • info@pcori.org • #PCORI2019 • www.pcornet.org • www.healthcore.com 11

Questions? 12

Thank You! Kevin Haynes, PharmD, MSCE Principal Scientist @khaynes001 9/20/2019 13