INTRO TO CODE BLUE ACS Slides 1 ¡
INTRO TO CODE BLUE ACS ① Anti- Anti-an angi ginal al � O2, nitroglycerin, morphine ② Anti-pl plat atel elet et � 1 st : ASA (162mg PO chewable) � 2 nd : P2Y 12 inhibitor (clopidogrel, ticagrelor, or prasurgrel – not if hx stroke/TIA) � 3 rd : glycoprotein IIb/IIIa inhibitor (consider at PCI) ③ Anti-coagu oagulat ation on � If fibrinolytics: UFH, LMWH, or fondaparinux � If PCI: UFH, bivalirudin, or UFH+bivalirudin ④ Revasc ascular arizat ation on � Fibrinolytics (TNK), PCI, or CABG ⑤ Risk sk fac actor or redu eduction on � Beta-blocker, ACEi/ARB, and Statin � Aldo antagonist (e.g. eplerenone): on BB/ACEi, either sx HF or DM, and EF<40% � Quit smoking 2 ¡
INTRO TO CODE BLUE ACS DOSES FOR SELECT MEDS Drug g Load oad Mai ainten enan ance e Durat ation on ASA 162mg PO 81mg/day Lifelong Clopidogrel 600mg pre-PCI 75mg/day 1 year 300mg lytics <24h 75mg > age 75 Ticagrelor 180mg 90mg BID 1 year Heparin IV bolus weight IV infusion 48h or until based (Goal 1.5-2x PTT) revascularization LMWH IV bolus weight SC injections Up to 8 days or until based revascularization ACEi - - Lifelong Beta-blocker - - Lifelong Statin - - Lifelong 3 ¡
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