WBMT Continental Regions 4 Continental regions used for the WBMT - PowerPoint PPT Presentation

WBMT Continental Regions 4 Continental regions used for the WBMT Global Analysis • AMR/PAH: Region of the Americas • EUR: European Region • EMR/AFR: Eastern Mediterranean/African Region • SEAR/WPR: South-East Asia/Western Pacific Region Worldwide Network for Blood and Marrow Transplantation NGO in official relations with World Health Organization

Origin of Global Data: Countries and participating institutions • 1 662 reporting transplant teams in 2016 • 1 739 of 89 ‘known to be active’ countries currently reporting since 2006 • AMR/PAH • United States: CIBMTR Canada: CBMTG • Argentina, Chile, Colombia, Costa Rica, Ecuador, Mexico, Panama, Paraguay, Peru, Uruguay, Venezuela: NATIONAL - LABMT • Brazil : SBMTO • EUR • 42 European countries: EBMT • EMR/AFR • Algeria, Egypt, Iran, Iraq, Jordan, Lebanon, Morocco, Oman, Pakistan, Qatar, Saudi Arabia, Tunisia: EMBMT . Nigeria, South Africa: AFBMT • SEAR/WPR • Bangladesh, China, Hong Kong, India, Japan, Malaysia, Mongolia, Myanmar, Nepal, Philippines, Singapore, South Korea, Sri Lanka, Taiwan, Thailand, Vietnam: APBMT. Australia, New Zealand: ABMTRR Worldwide Network for Blood and Marrow Transplantation NGO in official relations with World Health Organization

WBMT: maximum number of reporting teams per country: 1 739 8 1 14 7 6 26 2 1 4 3 54 16 2 6 18 112 20 9 2 5 1 1 13 75 10 6 1 5 1 3 4 100 198 2 1 2 1 73 1 6 62 13 45 381 88 2 1 2 1 2 9 3 2 2 1 3 3 18 1 7 13 3 67 1 1 3 2 3 11 2 3 3 1 2 1 13 6 5 3 The Americas 4 39 Eastern Mediterranean/Africa 1 42 5 Europe 7 5 21 South East Asia/Western Pacific 6 Not for publication

WBMT global survey: 2006-2016 Reporting teams N TX per team 1800 60 1600 50 1400 1200 40 1000 30 800 600 20 400 10 200 0 0 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Not for publication Worldwide Network for Blood and Marrow Transplantation NGO in official relations with World Health Organization

WBMT global survey: Main indications in 2016 Allogeneic HSCT IDM, 0,8% AID, 0,1% PID, 2,5% Other NMD, 0,5% HG, 3,3% Others, 0,6% BMF, 7,0% ST, 0,2% AML, 37,3% HD/NHL, 8,6% PCD, 1,7% Other leuk., 0,8% CLL, 1,2% MDS/MPS, 14,6% ALL, 17,9% CML, 2,9% Not for publication Worldwide Network for Blood and Marrow Transplantation NGO in official relations with World Health Organization

WBMT global survey: Main indications in 2016 Autologous HSCT Others, 0,1% AML, 1,48% AID, 1,4% ALL, 0,35% NMD, 0,1% MDS/MPN, 0,0% CML+CLL, 0,05% ST, 6,44% HD, 8,4% PCD, 53,5% NHL, 28,2% Not for publication Worldwide Network for Blood and Marrow Transplantation NGO in official relations with World Health Organization

WBMT global survey: Trend 2006-2016 Allogeneic vs autologous HSCT 50000 Autologous 40000 Allogeneic 30000 H S C 20000 T 10000 0 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Year Not for publication Worldwide Network for Blood and Marrow Transplantation NGO in official relations with World Health Organization

WBMT global survey: Trend 2006-2016 Donor type 22000 Unrelated Family 20000 18000 H 16000 S C 14000 T 12000 10000 8000 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Year Not for publication Worldwide Network for Blood and Marrow Transplantation NGO in official relations with World Health Organization

WBMT global survey: Trend 2006-2016 Donor choice 20000 Haplo incl. CB Unrelated incl CB Sibling/twin 15000 H S 10000 C T 5000 0 07 08 09 10 11 12 13 14 15 16 Not for publication Worldwide Network for Blood and Marrow Transplantation NGO in official relations with World Health Organization

WBMT global survey: Trend 2006-2016 Total HSCT by region 40000 EUR 35000 30000 AMR/PAH H 25000 S 20000 C SEAR/WPR T 15000 10000 EMR/AFR 5000 0 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Not for publication Worldwide Network for Blood and Marrow Transplantation NGO in official relations with World Health Organization

WBMT global survey: Trend 2006-2016 Allogeneic HSCT by region 18000 16000 EUR 14000 SEAR/WPR 12000 H 10000 S AMR/PAH C 8000 T EMR/AFR 6000 4000 2000 0 2006 2008 2010 2012 2014 2016 Not for publication Worldwide Network for Blood and Marrow Transplantation NGO in official relations with World Health Organization

WBMT global survey: Trend 2006-2016 Autologous HSCT by region 25000 EUR 20000 H 15000 AMR/PAH S C T 10000 SEAR/WPR 5000 EMR/AFR 0 2006 2008 2010 2012 2014 2016 Not for publication Worldwide Network for Blood and Marrow Transplantation NGO in official relations with World Health Organization

WBMT global survey: predicted activity 2020 1500000 Allo HSCT Auto HSCT Total HSCT 1200000 900000 600000 300000 0 1957 1959 1961 1963 1965 1969 1971 1973 1975 1977 1979 1981 1983 1985 1987 1989 1991 1993 1995 1997 1999 2001 2003 2005 2007 2009 2011 2013 2015 2017 2019 Not for publication Worldwide Network for Blood and Marrow Transplantation NGO in official relations with World Health Organization