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The Use of a Jet Jet- -PhoresisTransdermal PhoresisTransdermal Delivery System Delivery System The Use of a for Pain Control Pain Control - - ASLMS 2010 ASLMS 2010 - - ePoster ePoster Presentation Presentation for Ram Burvin, MD 1 ,


  1. The Use of a Jet Jet- -PhoresisTransdermal PhoresisTransdermal Delivery System Delivery System The Use of a for Pain Control Pain Control - - ASLMS 2010 ASLMS 2010 - - ePoster ePoster Presentation Presentation for Ram Burvin, MD 1 , Michael H. Gold MD 2 1 Craniofacial Plastic Surgery and Vascular Anomalies Centere, Tel-Aviv, Israel 2 Gold Skin Care Center, Nashville, TN Summary Current Study Design: Current Study Results: Background and • Prospective clinical study to • Statistically significant compare lidocaine jet-phoresis advantage of pain control in the Objective: trans-cutaneous anesthesia to lidocaine jet-phoresis group What is JetPeel? EMLA 5% topical cream compared to EMLA group (p<0.005) • 20 patients that were scheduled • A treatment based on to undergo needling roller for supersonic delivery of upper lip rhytids enrolled into study • Jet-phoresis lidocaine pain materials, including • Each patient served as own control was better or actives, to the skin control – 40 lips evaluated comparable to EMLA in > 82% of lips • Half of the upper lip had EMLA • Ability to simultaneously 5% cream applied for 45 minutes introduce active nutrients • Contra-lateral portion of the lip • Further confirmed by and oxygen into the skin, treated with lidocaine 3% jet- reversing the sides of the phoresis for 5 minutes tested lips in the same subjects using pressure and air • Pain elicited with needling roller uniformly applied across the upper lip • Pain response measured using VAS scale

  2. The Use of a Jet Jet- -PhoresisTransdermal PhoresisTransdermal Delivery System Delivery System The Use of a for Pain Control Pain Control - - ASLMS 2010 ASLMS 2010 - - ePoster ePoster Presentation Presentation for Background: Basic Principles • Pressurized gas is used to accelerate a liquid agent (saline). • Water droplets accelerated to supersonic velocities (200 m/s) • The mixture of liquid and gas is emitted through a special nozzle unit. • The high velocity jet exfoliates the superficial layers of the skin Supersonic Technology: • Supersonic two-phase jet directed onto the skin with specialized handpieces and nozzles. Supersonic jet flow • Spray consists of micro droplets of Opens intercellular channels saline or supplements (actives) and gas (air, oxygen or CO2). • High velocity spray induces skin rejuvenation through exfoliation and supplementation.

  3. The Use of a Jet Jet- -PhoresisTransdermal PhoresisTransdermal Delivery System Delivery System The Use of a for Pain Control Pain Control - - ASLMS 2010 ASLMS 2010 - - ePoster ePoster Presentation Presentation for Current Study Design: Skin Rejuvenation with Jet-Phoresis Restore youthful function and appearance • Prospective clinical study to by: compare lidocaine jet-phoresis • Reduces cellular buildup trans-cutaneous anesthesia to EMLA 5% topical cream • Exercise and strengthen capillary respiration • 20 patients that were • Remove metabolic waste from tissues scheduled to undergo needling • Hydrate, oxygenate tissues roller for upper lip rhytids enrolled • Provide nutritional support and protection into study • Energize cell renewal and wound healing • Each patient served as own process control – so 40 lips evaluated The nutritional elements that are used • Half of the upper lip had EMLA include: 5% cream applied for 45 minutes • Hyaluronic acid to enrich connective tissue • Contra-lateral portion of the lip treated with lidocaine 3% jet- • Vitamin C to improve dyschromias phoresis for 5 minutes • Vitamins E, B, and A for proper functioning of • Pain elicited with needling roller cells uniformly applied across the upper • Other potentials for Jet-Phoresis lip – Lidocaine administration • Pain response measured using – Toxin administration VAS scale

  4. The Use of a Jet Jet- -PhoresisTransdermal PhoresisTransdermal Delivery System Delivery System The Use of a for Pain Control Pain Control - - ASLMS 2010 ASLMS 2010 - - ePoster ePoster Presentation Presentation for Results: • Statistically significant advantage of pain control in the lidocaine jet-phoresis group compared to EMLA group (p<0.005) Before • Jet-phoresis lidocaine pain control was better or comparable to EMLA in > 82% Before of lips • Further confirmed by reversing the sides of the tested lips in the After 3 Treatments same subjects After 1 treatment

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