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The Nose in OSA Soup to Nuts Edward M. Weaver, MD, MPH University of Washington Harborview Medical Center Seattle VA Medical Center Acknowledgments This material is the result of work supported in part by resources from the VA Puget


  1. The Nose in OSA – Soup to Nuts Edward M. Weaver, MD, MPH University of Washington Harborview Medical Center Seattle VA Medical Center

  2. Acknowledgments • This material is the result of work supported in part by resources from the VA Puget Sound Health Care System, Seattle, Washington. • Dr. Weaver is a staff physician, surgery service line, Dept of Veterans Affairs Medical Center, Seattle, Washington.

  3. Disclosures • No industry disclosures • No off label therapies

  4. Notes • Adults • Split audience: – Otolaryngologists – Others

  5. Topics • Significance of nasal obstruction and treatment in OSA • Nasal evaluations, findings, therapies

  6. Upper Airway Anatomy

  7. Nasal Obstruction à Mouth Opening à

  8. Nasal Obstruction & CPAP Use Nasal obstruction â CPAP use. Nasal treatment á CPAP use.

  9. r = 0.34 CPAP Use p < 0.01 (hrs/nt) Nasal Minimum Cross-sectional Area (cm 2 ) Figure 5 Li, Sleep 2005; 28:1554-9

  10. Outcome Pre-Nasal Post-Nasal Pressure (cm) 11.6 ± 2.2 9.5 ± 2.0 * Acceptance 39% 90% Use (hr/nt) 3.0 ± 3.1 5.5 ± 2.0 *Beware All p<0.001 Camacho, Sleep 2015; 38:279-86

  11. Topics • Significance of nasal obstruction and treatment in SDB • Nasal evaluations, findings, therapies

  12. 1. Subjective

  13. Subjective Instruments • Nasal Obstruction Symptom Evaluation (NOSE) Scale • Nasal Obstruction VAS Stewart, OtoHNS 2004; 130:157-63 Stewart, OtoHNS 2004; 130:283-90

  14. 2. Nasal Valve

  15. Nasal Valve • Point of greatest resistance – Regulates airflow – Valve disorders important

  16. Nasal Valve Upper lateral cartilage Septum Turbinate

  17. Rhee, OtoHNS 2010; 143:48-59

  18. Nasal Valve Collapse

  19. Cottle Test

  20. Nasal Pillows

  21. Nasal Dilator Strip

  22. Nasal Dilator Insert

  23. Nasal Medication • Treat intranasal congestion • ↑ nasal caliber → ↓ neg force – Bernoulli’s Law • Indirect effect on valve collapse

  24. Otolaryngology Consultation • Nasal airway evaluation • Surgery evaluation

  25. 3. Nasal Cavity

  26. Nasal Cavity Exam • Speculum & headlight • Septum • Turbinates* • Allergy* • Polyps* *Medically treatable (partial)

  27. Nasal Valve Septum

  28. Septum Treatment • Surgical: Septoplasty

  29. Pre-Op Post-Op Septoplasty

  30. Valve Turbinate

  31. Turbinate Treatment • Irritant avoidance • Elevate head of bed • CPAP heated humidity • Nasal saline • Medications: – Nasal steroid – Anti-histamine – Oral decongestant – Nasal decongestant • Surgery: Turbinate reduction

  32. Turbinate Reduction

  33. Turbinate Reduction

  34. Poiseuille’s Law Radius 4 Flow = ———— x η Length

  35. Allergy Treatment • Allergen avoidance • Nasal saline • Medications: – Nasal steroid – Oral anti-histamine – Nasal anti-histamine – Nasal leukotriene modifiers • Desensitization therapy

  36. Polyp Treatment • Allergy treatment • Oral steroid • Surgery: – Endoscopic Polypectomy

  37. 4. Nasal Structure

  38. Nasal Deformity Treatment • Surgical

  39. Columellar Reduction Pre-Op

  40. Columellar Reduction Post-Op

  41. Men 22 ± 2 mm Women 21 ± 2 mm Erdem, Am J Rhinol 2004; 18:57-62

  42. Aperture Widening

  43. Nasal Valve Stabilization Weaver, Op Tech Oto 2012; 23:67-71

  44. Topics • Nasal airway significant • Nasal evaluation – Everyone can do basic evaluation – Otolaryngology for advanced eval • Nasal therapy – Medications safe & available – Often helpful – Surgical treatment backup

  45. The Nose and OSA – Soup to Nuts REFERENCES 1. Lee SH, Choi JH, Shin C, Lee HM, Kwon SY, Lee SH. How does open-mouth breathing influence upper airway anatomy? Laryngoscope 2007;117(6):1102-6. 2. Li HY, Engleman H, Hsu CY, et al. Acoustic reflection for nasal airway measurement in patients with obstructive sleep apnea- hypopnea syndrome. Sleep 2005;28(12):1554-9. 3. Camacho M, Riaz M, Capasso R, et al. The effect of nasal surgery on continuous positive airway pressure device use and therapeutic treatment pressures: A systematic review and meta-analysis. Sleep 2015;38(2):279-86. 4. Stewart MG, Witsell DL, Smith TL, Weaver EM, Yueh B, Hannley MT. Development and validation of the Nasal Obstruction Symptom Evaluation (NOSE) Scale. Otolaryngology-Head & Neck Surgery 2004;130(2):157-63. 5. Stewart MG, Smith TL, Weaver EM, et al. Outcomes after nasal septoplasty: Results from the Nasal Obstruction Septoplasty Effectiveness (NOSE) study. Otolaryngol Head Neck Surg 2004;130(3):283-90. 6. Rhee JS, Weaver EM, Park SS, et al. Clinical consensus statement: Diagnosis and management of nasal valve compromise. Otolaryngol Head Neck Surg 2010;143:48-59. 7. Erdem T, Ozturan O, Erdem G, Akarcay M, Miman MC. Nasal pyriform aperture stenosis in adults. Am J Rhinol 2004;18(1):57-62. 8. Weaver EM. Nasal valve stabilization. Operative Techniques in Oto 2012;23:67-71.

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