subsidiaries AN INTERNATIONAL PHARMACEUTICAL GROUP MdiS GROUP - PowerPoint PPT Presentation

MédiS GROUP

MédiS GROUP and its subsidiaries

AN INTERNATIONAL PHARMACEUTICAL GROUP MédiS GROUP Manufactures and markets generic medicines which comply with INTERNATIONAL STANDARDS

MédiS GROUP Tunisia Algeria Senegal Czech Republic

KEY DATES

Creation of MédiS The beginning of a story … Creation of the Creation of subsidiary Launch of the MédiS GROUP INPHA-MédiS Biosimilars project in Algeria Entry in the TOP 10 MédiS : leader of local industries The first MAA manufacturing Creation of Creation of Acquisition Creation of license MédiS NEAPOLIS of WPS TUNIVET of DPI Unit ► MédiS INTERNATIONAL PHARMA in Czech Republic Oncology and DPI SENEGAL

Manufacturing and marketing 2017/18 of Medicines in ALGERIA Manufacturing license of the new site and beginning of 2016 production 2013/14 Ranking TOP 20 laboratories Beginning of construction 2010 NEW site of production : DPI & Injectable forms 2006 Extension : Manufacturing of Merging and creation : dry forms INPHA-MédiS: Specialized in liquid forms THE LARGEST INJECTABLES SITE IN THE MENA

Manufacturing and marketing of Medicines in Czech Republic 2009 Start of the production in primary and secondary packaging (Tablets and Capsules ) 2008 The start of the project 2007 MédiS INTERNATIONAL Creation of MédiS INTERNATIONAL

Manufacturing and marketing of high-value added medicines 2018 Beginning of production and 2017 marketing Manufacturing license of the 2016 oncology site Manufacturing License of 2015 the DPI site Developpment of DPI & Oncology products 2011 Beginning of the project

Manufacturing and marketing of high-value added medicines Satisfy the local and regional needs in 100% Tunisian chemotherapy Investment and Biosimilar > 50 M DT medicines Respect of Best Manufacturing Practices and Security standards

13 Avril Manufacturing and marketing of medicines for West Africa 2017 MédiS 2008 Sénégal 2006 Winthrop Pharma Sénégal Africasoins Production 2000 1997 Aventis Pharma 1973 Rhône Poulenc (Entry and majority Creation of SIPOA shareholder) (Société Industrielle et Pharmaceutique de l’Ouest Africain)

Manufacturing and marketing of medicines for West Africa Winthrop Pharma Senegal (Ex SANOFI) becomes MédiS SENEGAL in 2017 MédiS SENEGAL employs 170 experimented people and is specialized in manufacturing and distribution of sterile ampoules, tablets and syrups in Senegal and sub-Saharan Africa Our Targets Widen the range by the Group products-portfolio Develop specific and essential medicines adapted to the needs of the area

MANUFACTURING UNITS TUNISIA

MédiS III Dry forms Social Bloc / NEAPOLIS PHARMA : Dry Powder for inhalation (DPI) Quality Control Laboratory MédiS II : Steril Form Warehouse MédiS I : Steril Form NEAPOLIS PHARMA : Oncology Unit Administration Access to the Site

First unit MédiS 5 000 m² I 7 lines of production for the injectable Injectable Forms Solid and liquid forms Biotechnology 5 000 m² MédiS DPI 2 lines of production of high capacity for II Oncology injectable Forms 7 000 m² MédiS 5 lines: oral solid and mono-dose liquids III automatic lines Unité d’Oncologie : 3 700 m² NEAPOLIS Injectable, oral and a dedicated Quality Control Laboratory DPI unit

Injectable Solid and liquid forms Biotechnology DPI 2 000 m² Quality Control Laboratory Oncology chemistry , microbiology et biotechnology Warehouse 6 000 Pallets

Technical team : 23 specialized staff Dedicated quality control laboratory : HPLC, Electrophoresis , ELISA, UV-Spectrophotometry … Specially dedicated lines : Injectable Forms, Lyophilisates, pre-filled Syringes Partnership and technology transfer with leaders in the sector Biotechnology

MédiS expansion into international markets

EXCHANGES OF EXPERTISE AND KNOW-HOW Production Commercial Sites : presence : TUNISIA SAUDI ARABIA ALGERIA UAE OMAN SENEGAL JORDAN LEBANON CZECH. REP YEMEN ---- IRAQ SYRIA ALGERIA LIBYA MOROCCO MAURITANIA FRANCOPHONE AFRICA ….. More than 1500 employees worldwide More than 125 Millions dollars of Turnover / year, in more than 25 countries Opening towards new horizons…

MédiS GROUP PORTFOLIO

INNOVATION IN THE STRATEGIC CHOICES LYOPHILISATES DENTAL CARTRIDGES PREFILLED SYRINGES ONCOLOGY DPI BIOTECHNOLOGY

NUMBER OF MAA OF THE GROUP WORLDWIDE : 1 235 280 In Tunisia 889 In Africa 62 In Midlle East 4 In Russia

THERAPEUTIC AREAS

CERTIFICATIONS AND MANUFACTURING LICENSE

CERTIFICATIONS AND MANUFACTURING LICENSE GMP STANDARDS European

CERTIFICATIONS AND MANUFACTURING LICENSE SPECIFIC STANDARDS Saudi Arabia

CERTIFICATIONS AND MANUFACTURING LICENSE SPECIFIC STANDARDS GHC

CERTIFICATIONS AND MANUFACTURING LICENSE SPECIFIC STANDARDS Jordan

CERTIFICATIONS AND MANUFACTURING LICENSE SPECIFIC STANDARDS Yemen

CERTIFICATIONS AND MANUFACTURING LICENSE SPECIFIC STANDARDS Sudan

CERTIFICATIONS AND MANUFACTURING LICENSE SPECIFIC STANDARDS Senegal GMP

CERTIFICATIONS AND MANUFACTURING LICENSE SPECIFIC STANDARDS Ivory Coast

CERTIFICATIONS AND MANUFACTURING LICENSE RED CROSS

CERTIFICATIONS AND MANUFACTURING LICENSE NEAPOLIS

CERTIFICATIONS AND MANUFACTURING LICENSE INPHA-MEDIS

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