BLOOD PRODUCTS STABLE PRODUCTS STEM CELLS HUMAN TISSUES Strategic partner for the Québec health system MOTHER’S MILK CORPORATE PRESENTATION
MISSION To efficiently meet the needs of the Québec population for quality blood and other biological products of human origin. VISION To become a strategic partner for the Québec health system.
BLOOD AND BIOLOGICAL PRODUCTS OF HUMAN ORIGIN SYSTEM IN QUÉBEC MINISTER OF HEALTH AND SOCIAL SERVICES HEALTH CANADA BIOVIGILANCE COMMITTEE HÉMA-QUÉBEC HOSPITALS DONORS RECIPIENTS 3
FROM SUPPLIER OF BLOOD PRODUCTS TO EXPERT IN BIOLOGICAL PRODUCTS OF HUMAN ORIGIN Adoption of the First cases of HIV Act Respecting transmitted through Héma-Québec blood – Contaminated Héma-Québec blood scandal starts its operations 1980 1989 1992 1996 1997 1998 Release of Creation of the unrelated the Gélineau bone marrow donor Committee registry in Canada report The Red Cross announces its withdrawal from the Canadian blood program as of September 1998 – Krever Commission report tabled 4
T IN BIOLOGICAL PRODUCTS OF HUMAN ORIGIN Creation of the no-fault compensation scheme Creation of the Creation of the Québec Public Québec Public Mothers’ Milk Cord Blood Bank Bank 2001 2003 2005 2011 2013 2014 Revision of the Operational start-up of the Act Respecting Héma-Québec : extended first GLOBULE mandate to biological Mobile Blood products of human origin Donation Unit – Opening of the Acquisition of the Mobile Blood Drive assets of the Centre Regional Centre de conservation de – tissus humains Opening of the first du Québec PLASMAVIE Plasma – Donor Lounge Opening of the first – GLOBULE Blood Donor Centre Héma-Québec assumes full management of the Stem Cell Donor Registry in Québec 5
HÉMA-QUÉBEC IS... CLOSE TO 225,000 BLOOD, STEM CELL, MOTHER’S MILK AND HUMAN TISSUE DONORS A great team dedicated to the gift of life THOUSANDS 1,347 OF VOLUNTEERS EMPLOYEES 2017–2018 ANNUAL REVENUE $450M 6
PERMANENT PRESENCE THROUGHOUT QUÉBEC Facility GLOBULE Mobile Blood Drive Regional Centre PLASMAVIE PLASMAVIE with a blood donation area Saguenay Drop-off point for mother’s milk NEW (June 2018) Québec Saint-Laurent Arrondissement Sainte-Foy NEW Quartier Lebourgneuf (June 2018) Trois-Rivières NEW (Fall 2018) Montréal Sherbrooke Laval Gatineau Brossard NEW (April 2018) 7
BLOOD PRODUCTS Justine makes her first blood donation. 8
COLLECTIVE BLOOD SUPPLY 304,920 BLOOD PRODUCTS DELIVERED 173,244 DONORS PER YEAR (all types of donations) generated over 357,039 visits to collection sites 2,416 COLLECTION METHODS 73% MOBILE BLOOD DRIVES MOBILE BLOOD DRIVES 20% CENTRES organized each year 7% (including blood drives in mobile units) MOBILE UNITS BLOOD PRODUCTS DONATION FROM DONATION TO DISTRIBUTION The blood collection takes about ten minutes. In addition to the blood bag (450 ml), samples are collected for analysis. DELIVERY TRANSPORTATION Products are delivered The blood bags and their samples to hospitals. The blood are packed and sent to one of components used vary Héma-Québec’s laboratories. depending on the patient. ANALYSES STORAGE The blood samples collected Compliant products are during the donation are sent labeled and stored, ready to the qualification laboratory for shipment to hospitals. to screen for infections. SEPARATION OF WHOLE BLOOD The blood is separated into its various components (red blood cells, platelets or plasma).
STABLE IMPROVING SELF-SUFFIENCY IN PLASMA PRODUCTS INTENDED FOR MEDICATION MANUFACTURING Self-sufficiency rate in immunoglobulin relies on the generosity of our donors. SELF-SUFFICIENCY RATE IN IMMUNOGLOBULIN 21.5 % OF IN 2017–2018 105,160 LITRES OF PLASMA collected for purposes of manufacturing medications 10
MEDICATIONS MANUFACTURED FROM PLASMA EXCLUSIVE DISTRIBUTION for 427,822 Québec STABLE PRODUCTS delivered in 2017–2018 50 DIFFERENT Some PRODUCTS DISTRIBUTED PRODUCTS MANUFACTURED BY MANUFACTURED including PHARMACEUTICAL 4 from plasma collected COMPANIES by Héma-Québec under agreement with Héma-Québec STABLE PRODUCTS FROM DONATION TO DISTRIBUTION DONATION Plasma donations are made in donor centres, by appointment. The collection process lasts approximately 45 minutes. FREEZING Plasma is quickly frozen following DELIVERY collection. The faster you freeze it, Products are delivered the more protein you can extract. to hospitals. ANALYSES RETURN OF PRODUCTS Collections are sent to the TO HÉMA-QUÉBEC qualification laboratory. AND STORAGE All donations are tested. The finished products are then returned to Héma-Québec and stored, ready for shipment to hospitals. FRACTIONATION The plasma is sent to fractionation plants. These high-tech plants extract proteins from plasma and use them to make medications.
STEM STEM CELL DONOR REGISTRY CELLS 45,690 registered donors in Québec to meet the needs of patients requiring a stem cell transplant Héma-Québec is a part of a global network that includes 32 MILLION DONORS Rosalie, cord blood recipient 12
PUBLIC CORD BLOOD BANK 17 Internationally Netherlands recognized 1 11 Austria expertise England 56 8 Canada France 2 27 2 Italy Turkey 1 United States Israel 1 2 Argentina Australia 128 UNITS 11 10,776 9 PARTNER FIRST BANK DISTRIBUTED HOSPITALS IN CANADA UNITS DISTRIBUTED THROUGHOUT THE UNITS BANKED IN 2017–2018 WORLD SINCE 2008 FROM DONATION TO TRANSPLANT DONATION Cord blood is collected at birth in partner hospitals. TRANSPORTATION TRANSPLANT Cord blood is transported STEM CELLS The patient receives to Héma-Québec. the transplant. CALL AND RESEARCH When our registry receives a call, QUALIFICATION we search for a compatible unit for a patient in need of a stem cell Cord blood is qualified transplant. based on strict criteria. PROCESSING AND STORAGE Cord blood is processed, frozen at −150 °C and stored -150 °C for 15 years. The units of cord blood are made available through a world registry.
HUMAN TISSUES Claudie-Ann, customer service agent (human tissues), handles musculoskeletal products. 14
HUMAN TISSUE BANK Héma-Québec collects the IN 2017–2018 following human tissues: 5,451 Ocular tissues (corneas, scleras) TISSUES DISTRIBUTED Heart valves to hospitals Skin tissues 1,008 DONORS WHO DONATED in Québec Arterial tissues (abdominal aortas, arteries...) 5,464 Musculoskeletal tissues (tendons, bone chips, femoral heads...) DONOR REFERRALS FROM DONOR REFERRALS HUMAN TISSUES TO TRANSPLANT DONOR REFERRALS Health professionals recommend donors to Héma-Québec. TRANSPLANT CONSENT A verification of the consent registries The surgeon transplants the is made. Whether consent is registered tissues. One human tissue or not, it is important for the donor to donation can help up to 20 people. inform his or her loved ones if he or she consents to the donation of human tissues, since they will be the ones who will speak on his or her behalf at the PROCESSING AND STORAGE time of his or her death. The tissues are processed and stored until they are transplanted. Most tissues can be preserved for up to five years, with the exception of QUALIFICATION corneas that cannot be preserved Héma-Québec conducts a beyond 14 days. thorough evaluation to verify the donor’s eligibility. COLLECTION Héma-Québec performs the collection of human tissues.
MOTHER’S MILK Mévick received mother’s milk at birth. 16
PUBLIC MOTHERS’ MILK BANK FOR VERY PRETERM INFANTS IN 2017–2018 11,767 853 BOTTLES DISTRIBUTED REGISTERED DONORS FROM DONATION TO DISTRIBUTION DONATION Héma-Québec supplies the bottles; mothers collect their milk at home and freeze it. MOTHER’S MILK DELIVERY PICK-UP AND DROP-OFF POINT The milk is distributed to hospitals Depending on the region, for very premature infants who cannot be breastfed by their mothers. Héma-Québec collects the bottles at the donor’s home or the donor brings the milk to a drop-off point. MICROBIOLOGICAL ANALYSES AND STORAGE Héma-Québec tests the milk MICROBIOLOGICAL to ensure that it is safe for ANALYSES recipients; if the results are Héma-Québec conducts tests satisfactory, the milk is frozen on the unpasteurized milk to and stored for a year. ensure that it meets quality standards. PASTEURIZATION DONATION POOLING The milk is pasteurized to eliminate Héma-Québec combines donations viruses and bacteria. from several donors into one batch.
SPECIALIZED LABORATORY SERVICES FOR HOSPITALS 4,704 testing requests received from hospitals Erythrocyte Complex cases genotyping in erythrocyte of blood groups immunology 3,783 1,470 ANALYSES ANALYSES (patients cases (patients cases) and donors) Screening for Phenotypimg virological markers 21,114 1,715 PHENOTYPED ANALYSES PACKED RED (donors in hospitals) BLOOD CELLS distributed 18
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