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ST-elevation in aVR and ST depression in all other leads ACCA - PowerPoint PPT Presentation

A patient with chest pain and ST-elevation in aVR and ST depression in all other leads ACCA Masterclass 2017 Sofie Gevaert Mr LP, 55-years-old History: Hypertension, treated with Perindopril 5mg and Nebivolol 5mg Current:


  1. A patient with chest pain and ST-elevation in aVR and ST depression in all other leads ACCA Masterclass 2017 Sofie Gevaert

  2. Mr LP, 55-years-old History: • • Hypertension, treated with Perindopril 5mg and Nebivolol 5mg Current: • • 01.00 am: progressive severe thoracic pain radiating to left arm • Orthopnoea • 112  Medical emergency team Other CV risk factors: • • Hyperlipidaemia • Obesity • Sudden death of father at 50 y ACCA Masterclass 2017

  3. MET 08.00 am: parameters, clinical exam BP 142/72 mmHg, HR 160 bpm, regular, SaO 2 88%, Resp R • 27/min Clammy, cold extremities • No jugular distension • No cardiac murmur • Bilateral crepitations • No peripheral edema • ACCA Masterclass 2017

  4. FMC in patient with chest pain ACCA Masterclass 2017 ACCA toolkit 2015

  5. ECG 08.05 am ACCA Masterclass 2017

  6. 1. ER: Patient with chest pain, 08.28 am ACCA Masterclass 2017 ACCA toolkit 2015

  7. Further strategy? Further stabilisation, diagnostics in ER? • Direct transfer to cathlab? • ACCA Masterclass 2017

  8. 2. ER: dyspnoea, orthopnoea ACCA Masterclass 2017 ACCA toolkit 2015

  9. Chest X-ray 08.32 am Furosemide 40mg IV (MET) ACCA Masterclass 2017

  10. Quick look echo ACCA Masterclass 2017

  11. ? ACCA toolkit 2015

  12. CONGESTION - + H Y P O _ P E R ESC guidelines AHF 2015 F U S + I O n ACCA Masterclass 2017

  13. ACCA Masterclass 2017 ACCA toolkit 2015

  14. 08.45 am Ongoing chest pain despite high dose opioids • SaO 2 90 despite FiO 2 90% • Persisting respiratory failure despite initial measures • Troponin T 435 ng/L, creatinine 2.1 mg/dL (CKD-EPI 30 mL/min), Hct 42% • PH 7.24, PCO 2 47mmHg, lactate 34.1 mg/dL (<11.3 mg/dL, =3.8mmol/L) • Sedation, Intubation ACCA Masterclass 2017

  15. Invasive strategy: Timing, antithrombotic R/ and access Timing? • Antiplatelet? • • None • ASA mono • DAPT Anticoagulation? • • None • UFH • LMWH • Fondaparinux • Bivalirudin Access? • ACCA Masterclass 2017

  16. Timing ACCA Masterclass 2017 ACCA toolkit-ESC guidelines NSTE-ACS2015

  17. ACCA Masterclass 2017 ACCA toolkit 2015

  18. Ischemic risk ACCA Masterclass 2017

  19. Bleeding risk ACCA Masterclass 2017

  20. High ischemic and high bleeding risk KD and shock state UFH 5000 IU bolus ASA 200mg IV ESC guidelines NSTE-ACS 2015 ACCA Masterclass 2017

  21. Coronary angiography 09.20 am Shock, peripheral VC: Femoral access ACCA Masterclass 2017

  22. CT angiography 09.50 am ACCA Masterclass 2017 ESC guidelines Aortic dis. 2014

  23. Type A dissection with dissection left main Urgent surgery • • Tear ascending aorta • Urgent surgery:Hemiarch Sinotubular junction  proximal arch • Postoperative: stroke, AKI • Rehab program ACCA Masterclass 2017

  24. THANK YOU ACCA Masterclass 2017 Sofie Gevaert

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