R eal Time Lethbridge Entrepreneurial iGEM Team iGEM World Jamboree - PowerPoint PPT Presentation

B iologically E nhanced A ssay in R eal Time Lethbridge Entrepreneurial iGEM Team iGEM World Jamboree November 3 rd , 2013

Our Team Web Manager Chief Chief Co-Chief Co-Chief Science Officer Science Officer Executive Operational Officer Officer Harland Isaac Ward Erin Kelly Mackenzie Amrinder Brandon Coatham Grewal

Our Concept and Development: Hormone Detection Over expressed Protein Single Unit Module Over expression of Protein A Multi Unit Module Currently evaluating Canadian, US and EU health and medical device regulations

Market Demographic BEAR will be valuable to Researchers and Diagnosticians in the endocrinology and neuroscience fields Canada 447 endocrinologists 78% work in an academic health sciences centre 37% work in a university United States 5341 endocrinologists 28% of these are involved in research Canadian Society of Endocrinology and Metabolism: http://www.endo-metab.ca/ The Endocrine Society: http://www.endo-society.org/media/press/2008/Endocrinology-Workforce-Shortage- Represents.cfm#

Conventional Methods Market Size Worldwide Sales of Therapeutic Monoclonal and Companion Diagnostics, 2005-2012 The global market for monoclonal therapeutic and diagnostic antibodies increased from $26 billion in 2006 to an estimated $31 billion by the end of 2007 and $56 billion by 2012. Compound annual growth rate of 13%. lhttp://www.bccresearch.com/report/monoclonal-therapeutics-products-bio016g.html

Canadian Biotechnology Market Size

Medical Applications Canadian and United States Births from 1920’s -2009/2011 Figure 1 Canadian births 1921-2009 Figure 2 Live births and fertility rates: United States, 1920-2011 Statistics Canada: http://www.statcan.gc.ca/pub/84f0210x/2009000/t031-eng.pdf Martin JA, Hamilton BE, Ventura SJ, et al. Births: Final Data for 2011. National Vital statistics reports; vol 62 no 1. Hyattsville, MD: National Center for Health Statistics. 2013 .

Canadian Health Care Equipment Market

Canadian Medical Device Industry Advantage • Medical Device Manufacturing Costs Lowest in G7, along with the lowest operating costs • Low R&D Costs and Tax Incentives • Regulatory Process Emphasizes Harmonization • Supportive Network of Industry Associations • Federally Funded Research Support Programs • CIHR, NRC, NSERC Canadian medical device industry profile

Business Model Licence Direct Sales Synbiologica Ltd. Established Biotech Company • Determine Customer Needs • Marketing • Proof of Principle • Manufacturing Final Customer • Develop Prototype • Advertising • Acquire Patents for • Distribution Licensing • Sales Royalties Revenue

Revenue Model Monitoring Device $ Repeated Use One Time Sales $ $ $ $ $ $ $ Disposable Unit One Time Use Recurring Sales

Customer Strategy Endocrinology Research Visibility and Market Demand Publications Livestock Agriculture Human Diagnostics

Financial Model 400,000 300,000 200,000 Income 100,000 expenses 0 net Income Year 1 Year 2 Year 3 Year 4 -100,000 -200,000 -300,000 20,000,000 18,000,000 16,000,000 14,000,000 12,000,000 10,000,000 8,000,000 6,000,000 4,000,000 2,000,000 0 Year 5 Year 6

Skills Value of the iGEM Experience Knowledge-Translation International Networking Team-Work Creative-Solutions Collaboration Public-Speaking Organization Goal Setting Presentation Problem-Solving Project-Management Grant-Writing Multidisciplinary Economics Ethics Community Politics Responsibility Values Entrepreneurship Fund-Raising Community-Involvement Public Policy Leadership

Progress and Achievements Chinook Entrepreneur Challenge South Venture Business Plan Competition: Winner Technology Stream: Winner Insurance First Business Cards Presentation Business Plan Executive Summary First Request 2012 CEC Training for Proposal Synbiologica Limited is Incorporated - March 14, 2013 (Pi Day)

Acknowledgements Advisors Dr. Gerlinde Metz Mr. Michael Kelly Dr. HJ Wieden Mr. Dan Kazakoff Dr. Roy Golsteyn Mr. & Mrs. Cotham Local Business and Technology Advisors Mr. Bill Halley Ms. Renea Barlow Dr. Morgan Guo Mr. Geoff Rougeau Mr. Cal Koskowich Mr. K. Greg Senda Local Support Networks University of Lethbridge and the Office of Research Services Regional Innovation Network of Southern Alberta Community Futures Economic Development Lethbridge Dr. Dan Polonenko – Gowlings

Sponsors and Support