COMPANY PRESENTATION Date | May 2020 Location | Bubendorf, Switzerland Name | Erik Schrader, PhD
LEADING SINCE 1971 • Dedicated to peptides and oligonucleotides • Working on a global scale • Public company since 1998 (Swiss Stock Exchange) 1 Bachem Company Presentation 2020
BACHEM LOCATIONS TORRANCE (CA) BUBENDORF (CH) Acquired in 1996 Founded in 1971 VISTA (CA) TOKYO (JP) Acquired in 2015 Established in 2018 ST.HELENS (UK) VIONNAZ (CH) Acquired in 1999 Acquired in 2001 GMP Sites 2 Bachem Company Presentation 2020
Research & Development • Catalog peptides and custom synthesis services Custom Manufacturing • Process development and validation • Production of peptides for preclinical and clinical phases BACHEM IS Commercial Supply YOUR TRUSTED PARTNER • Supply of (multi-) kilograms to tons of cGMP API (launch quantities, manufacturing of API for marketed drugs) • Peptide and small molecule generics 3 Bachem Company Presentation 2020
PRODUCTS PORTFOLIO AND SERVICES 4 Bachem Company Presentation 2020
Research Institutes, Universities and Industrial R&D CATALOG Product portfolio of over 6500 catalog Easy ordering PRODUCTS peptides and biochemicals & fast delivery at shop.bachem.com • Research and bulk quantities available from stock (mg to kg) • Peptides, amino acid derivatives, inhibitors, substrates, resins, linkers, reagents • Bachem Quality Grade starting materials 5 Bachem Company Presentation 2020
Healthcare, Biotech, and Pharmaceutical Companies • Peptide synthesis from mg/g to kg scale CUSTOM • Development of synthetic routes for Dedicated site SYNTHESIS scale up for Custom Synthesis • Cosmetic peptides • Diagnostic peptides for medical devices acc. to ISO 13485 • High quality and timely delivery 6 Bachem Company Presentation 2020
Modifications Labeling & Conjugation Backbone Modifications Biotinylated Peptides Dye-labelling with standard and Branched Peptides patented dyes (including Tide Fluor™ C/N-terminal Modifications dyes and quenchers) OUR TEAM IS Clickable Peptides Heavy Isotope Labeling Cyclic Peptides EXPERIENCED FRET or TR-FRET Peptides Hydrocarbon-Stapled Peptides PEGylated Peptides IN A LARGE Unnatural & Unusual Amino Acids Conjugation to Imaging Agents, Proteins SELECTION OF (BSA, KLH), Oligonucleotides Methylation PEPTIDE Multiple Disulfide Bond Formation MODIFICATIONS Peptidomimetics Further specialties Depsipeptides, MAP and Maleimido Peptides, Lipidation, Phosphorylation, Sulfation (…..) 7 Bachem Company Presentation 2020
Biotech and Pharmaceutical Companies CUSTOM • Development and manufacturing of DEVELOPMENT Our APIs from early clinical trials to project team is AND commercialization your proactive • Process development, optimization and partner MANUFACTURING validation OF NCE S • Quality by design • Production of launch quantities 8 Bachem Company Presentation 2020
Biotech and Pharmaceutical companies • Trusted supplier Peptide • Strong reputation for sustained quality & & GENERIC APIs supply Small Molecule Generics • Long term collaborative partnerships • Generic APIs are available from stock in commercial quantities 9 Bachem Company Presentation 2020
• Independent CMO with 50 years proven track record of peptide innovation and manufacturing expertise • Our products and services support our partners through all stages of drug development BACHEM • Highest industry standard for quality assurance, control, and PIONEERING PARTNER regulatory compliance FOR PEPTIDES SINCE 1971 • Excellent project management record with the world’s leading pharmaceutical and biotechnology companies • Sustainable long-term partnership with all stakeholders 10 Bachem Company Presentation 2020
OFFICE LOCATIONS www.bachem.com www.bachem.com www.bachem.com Bachem Americas, Inc. Bachem AG Bachem Japan K.K. No matter where you are located, Torrance, CA 90505 4416 Bubendorf Tokyo 103-0012 USA Switzerland Japan Bachem has the expertise and resources to help you and your Tel +1 888 422 24 36 Tel +41 585 95 20 21 Tel +81 3 6661 0774 organization excel in life science research and pharmaceutical E-Mail sales.us@bachem.com E-Mail sales.ch@bachem.com E-Mail sales.jp@bachem.com drug development. 11 Bachem Company Presentation 2020
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