Modulation of plant TPC channels by polyunsaturated fatty acids Paul - PowerPoint PPT Presentation

Modulation of plant TPC channels by polyunsaturated fatty acids Paul Vijay Kanth Gutla, Anna Boccaccio, Alexis De Angeli, Franco Gambale and Armando Carpaneto Supplementary material: Supplemental Fig. 1 Supplemental Fig. 2 Supplemental Table 1

acid structure abbreviation DHA docosahexaenoic 22:6 ! -3 AA arachidonic 20:4 ! -6 ALA linolenic 18:3 ! -3 LA linoleic 18:2 ! -6 OA oleic 18:1 ! -9 ARA arachidic 20:0 PA palmitic 16:0 CH 3 Me-DHA docosahexaenoic-me CH 3 Me-ALA linolenic-me Supplemental figure 1: List of fatty acids used in this study. ¡

Supplemental figure 2: Three-dimensional conformation of the different fatty acids used in the experiments. It is visible that fatty acids harbouring a higher number of double bonds in the acyl- chains present a more compact folding. The efficacy of inhibition of the fatty acid correlates with the highest degree of bending of the fatty acid. Atoms are: grey carbon, red oxygen, white hydrogen. ¡