House MD: Solving Complex IT Issues Using Differential Diagnosis Steve Bennett Steve@DaemonSolutions.com @DaemonSteve Saturday, 30 June 12
AGENDA A Brief History Of Medical Diagnosis. Why & How You Should Prove Yourself Wrong. Differential Diagnosis. Diagnostic Approaches. Diagnostic Thresholds. Do’s, Don’ts & Application. Saturday, 30 June 12
Who’s This Guy? Saturday, 30 June 12
Why...? Saturday, 30 June 12
Saturday, 30 June 12
http://www.technologyreview.com/tr35/profile.aspx?TRID=1108 Saturday, 30 June 12
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http://flic.kr/p/npaoT Saturday, 30 June 12
http://4.bp.blogspot.com/_lSXhEtQUdtA/S-EL5w7dt3I/AAAAAAAAANE/G0oc_cGPXAY/s320/USAirways+in+the+water.jpg Saturday, 30 June 12
Medical Diagnosis Saturday, 30 June 12
http://4.bp.blogspot.com/-cCTr1WWve1E/TfefWAn8zvI/AAAAAAAAAA0/aXO50-syXuE/s1600/Imhotep_Museum-hd-1.jpg Imhotep - 2600BC Saturday, 30 June 12
http://en.wikipedia.org/wiki/File:Edwin_Smith_Papyrus_v2.jpg Saturday, 30 June 12
http://www.sculpturegallery.com/two/hippocrates3.jpg Hippocrates - 460BC Saturday, 30 June 12
http://www.sculpturegallery.com/two/hippocrates3.jpg Galen - AD131 Saturday, 30 June 12
In Summary; It’s Been Around A Long Time.. Saturday, 30 June 12
Hypothetico-Deductive Model Saturday, 30 June 12
William Whewell Saturday, 30 June 12
"No amount of experimentation can ever prove me right; a single experiment can prove me wrong." Albert Einstein Saturday, 30 June 12
Hypothetico-deductive model Saturday, 30 June 12
Something unexplained happens. Saturday, 30 June 12
http://www.flickr.com/photos/dougcaldwell/4213877479 Hypothesize. Saturday, 30 June 12
Plan a test that can falsify . Predict the result. Saturday, 30 June 12
Test. http://www.flickr.com/photos/kenilio/3351824931 Saturday, 30 June 12
Hypothesize. Plan a test that can falsify. Predict. Test. Saturday, 30 June 12
An Example. Saturday, 30 June 12
I went shopping.. Saturday, 30 June 12
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Failed Card http://flic.kr/p/9MShdE Saturday, 30 June 12
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Hypothetico-deductive model Saturday, 30 June 12
Something unexplained happens. Saturday, 30 June 12
Hypothesise. Saturday, 30 June 12
I’ve Spent Too Much On SSD’s My Wife Has Been Shopping Hypothesise. There Is A System Problem I Didn’t Pay My Bill In Time Saturday, 30 June 12
Plan a test. Predict. Saturday, 30 June 12
Test: I’ll call the credit card company. Plan a test. Predict. Saturday, 30 June 12
Test: I’ll call the credit card company. Plan a test. Predict. Prediction: I have sufficient funds. (If correct will falsify 3 hypothesis) Saturday, 30 June 12
Test. Saturday, 30 June 12
Test. Result: I have sufficient funds. Saturday, 30 June 12
I’ve Spent Too Much On SSD’s My Wife Has Been Shopping Hypothesise. There Is A System Problem I Didn’t Pay My Bill In Time Saturday, 30 June 12
Hypothesise. There Is A System Problem Saturday, 30 June 12
Hypothetico-Deductive Model Hypothesise. Plan a test that can falsify . Predict. Test. Saturday, 30 June 12
Differential Diagnosis. Saturday, 30 June 12
Or DDx Saturday, 30 June 12
What is it? Saturday, 30 June 12
It’s that thing that House does. Saturday, 30 June 12
It's a framework for problem diagnosis. Saturday, 30 June 12
It's best used alongside the hypothetico-deductive model. Saturday, 30 June 12
Process of elimination. Saturday, 30 June 12
Assume most obvious. Until proved otherwise. Saturday, 30 June 12
"When you hear hoof beats, look for horses, not zebras" Saturday, 30 June 12
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Probability is your friend. http://www.flickr.com/photos/nashnosh/5922580484 Saturday, 30 June 12
Personalised probability is your best buddy. http://www.flickr.com/photos/el5ajoola/3868649830 Saturday, 30 June 12
Here’s how it works. Saturday, 30 June 12
Something happens. Saturday, 30 June 12
Something bad happens. Saturday, 30 June 12
Something bad and complicated happens. Saturday, 30 June 12
Gather the facts... Saturday, 30 June 12
Gather the facts... Symptoms Saturday, 30 June 12
Gather the facts... Symptoms Subject history Previous test results General observations Saturday, 30 June 12
What else do we know? Saturday, 30 June 12
http://www.flickr.com/photos/dougcaldwell/4213877479 Hypothesise. Saturday, 30 June 12
List Hypotheses. Saturday, 30 June 12
Immediately discount. Apply probability. Saturday, 30 June 12
Prioritise hypothesis based on risk and probability. Saturday, 30 June 12
Plan tests. Predict results. Saturday, 30 June 12
Test. Or Treat. Saturday, 30 June 12
Feedback results. Saturday, 30 June 12
Continue until diagnosis is confirmed. http://www.o-min.com/wp-content/uploads/mobius1-300x225.jpg Saturday, 30 June 12
Differential Diagnosis. Gather the facts. Hypothesise. Apply Probability. Prioritise. Test or Treat. Loop. Saturday, 30 June 12
Diagnostic Approach Saturday, 30 June 12
Possibilistic Saturday, 30 June 12
Possibilistic All Possibilities Are Equal Test Everything Saturday, 30 June 12
Possibilistic All Possibilities Are Equal Test Everything Saturday, 30 June 12
Probablistic Saturday, 30 June 12
Probablistic Selection Based On Probability Prioritise The Most Likely Saturday, 30 June 12
Probablistic Selection Based On Probability Prioritise The Most Likely Saturday, 30 June 12
Prognostic Saturday, 30 June 12
Prognostic Selection Based On Most Serious Prioritise The Most Serious Saturday, 30 June 12
Prognostic Selection Based On Most Serious Prioritise The Most Serious Saturday, 30 June 12
Pragmatic Saturday, 30 June 12
Pragmatic Selection Based On Responsiveness To Treatment Prioritise The Most Easily Treated Saturday, 30 June 12
Pragmatic Selection Based On Responsiveness To Treatment Prioritise The Most Easily Treated Saturday, 30 June 12
When do I use each approach.. Saturday, 30 June 12
Do something and do it fast... Pragmatic. Saturday, 30 June 12
If it really is that, we are in a world of hurt. Prognostic. Saturday, 30 June 12
Default = Probabilistic. Saturday, 30 June 12
I want more probability... Saturday, 30 June 12
Pre & Post Test Probability. Current Probability: 30% If the result is X; There is 60% chance of hypothesis being correct. If the result is Y; There is 0% chance of hypothesis being correct. Saturday, 30 June 12
This is easier in medicine. Saturday, 30 June 12
Differential Diagnosis... ! Diagnostic Approach... ! Saturday, 30 June 12
Diagnostic Thresholds Saturday, 30 June 12
Define the point at which something is worth testing. Saturday, 30 June 12
Probability of Diagnosis 0% 100% Test Treatment High Priority Tests Threshold Threshold Not Worth Worth Worth Testing Testing Treating Saturday, 30 June 12
Mnemonics. Saturday, 30 June 12
Doctors Love Mnemonics. Saturday, 30 June 12
Mnemonic for DDx. Saturday, 30 June 12
Vascular Idiopathic/Intoxication Neoplastic Degenerative/Deficiency Inflammatory Congenital Autoimmune/Allergic Traumatic Endocrine Saturday, 30 June 12
Mnemonic for Acute Pancreatitis. Saturday, 30 June 12
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