Gloria Kolb Need for Retinal Implants Retinal Degeneration: Whats - PowerPoint PPT Presentation

PROTEIN-BASED RETINAL IMPLANT ~ RESTORING VISION ~ Gloria Kolb

Need for Retinal Implants

Retinal Degeneration: What’s the Problem?

The Implant  Thin, tiny flexible implant  Three main components Flexible, ion-permeable membrane  Positively charged polymer  Light activated protein – bacteriorhodopsin   One-time out-patient surgery

Advantages Over Competition  Gene therapy-  Electronic low-resolution very early stage pixels of development http://www.nytimes.com/2011/05/17/science/17optics.html?pagewanted=all&_r=0 http://accessscience.com/popup.aspx?id=YB110084&name=print http://www.bostonretinalimplant.org/

How we know it will work  Stimulated neural circuitry of RP rat retinas  Activated using ambient light

Expertise  Robert R. Birge, Founder  35+ years in vision research  Expert in bacteriorhodopsin- based devices CT Medal of Science 

Commercialization  3 US Patents  Manufacture, package, and sterilize implant  Biocompatibility  Surgical development and tool  Orphan Drug Indication (Combination Product) GMP production (ongoing) Safety and efficacy in vivo work (2013-2014) IND application (2014-2015) Clinical trials (2015-2016) NDA (2016-2017)

Profitable  Reimbursement @ $60,000 90+% PROFIT!!  Looking for industry partners and venture capital www.LambdaVision.com 860-679-7016