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Structured stochastic processes and functional data analysis for the assessment of motor learning in normal and pathological subjects (Postdoctoral research submitted to FAPESP) Noslen Hernndez Antonio Galves, Claudia Vargas II NeuroMat


  1. Structured stochastic processes and functional data analysis for the assessment of motor learning in normal and pathological subjects (Postdoctoral research submitted to FAPESP) Noslen HernΓ‘ndez Antonio Galves, Claudia Vargas II NeuroMat Workshop: New Frontiers in Neuromathematics November 2016

  2. Recent results [ A. Duarte, R. Fraiman, A. Galves, G. Ost and C.D. Vargas, arXiv:1602.00579 ] o Hypothesis: The brain retrieves statistical regularities from stimuli

  3. Recent results [ A. Duarte, R. Fraiman, A. Galves, G. Ost and C.D. Vargas, arXiv:1602.00579 ] o Hypothesis: The brain retrieves statistical regularities from stimuli o Definition of new kind stochastic processes

  4. Recent results [ A. Duarte, R. Fraiman, A. Galves, G. Ost and C.D. Vargas, arXiv:1602.00579 ] o Hypothesis: The brain retrieves statistical regularities from stimuli o Definition of new kind stochastic processes Stochastic process driven by context tree model

  5. Recent results [ A. Duarte, R. Fraiman, A. Galves, G. Ost and C.D. Vargas, arXiv:1602.00579 ] o Hypothesis: The brain retrieves statistical regularities from stimuli o Definition of new kind stochastic processes Stochastic process driven by context tree model o Allows a design, modeling and analysis of neurophysiological experiments with structured stimuli

  6. Retrieving a context tree form EEG data Random Source Images taken from [A. Duarte, R. Fraiman, A. Galves, G. Ost and C.D. Vargas, arXiv:1602.00579]

  7. Retrieving a context tree form EEG data Random Source Images taken from [A. Duarte, R. Fraiman, A. Galves, G. Ost and C.D. Vargas, arXiv:1602.00579]

  8. Retrieving a context tree form EEG data Random Source Images taken from [A. Duarte, R. Fraiman, A. Galves, G. Ost and C.D. Vargas, arXiv:1602.00579]

  9. Retrieving a context tree form EEG data Random Source π‘Œ 1 , 𝑍 1 , … , π‘Œ π‘œ , 𝑍 o π‘œ o New statistical model selection procedure for FD o The brain effectively identifies the context tree characterizing the source. Images taken from [A. Duarte, R. Fraiman, A. Galves, G. Ost and C.D. Vargas, arXiv:1602.00579]

  10. Can such finding be corroborated in behavioral responses, specifically in execution of movements? Images taken from https://www.lvhn.org/for_referring_physicians/better_medicine/rehabilitation/neuromuscular_rehabilitation_technology_helps_patients_i ncrease_motor_control; http://neuromat.numec.prp.usp.br/pt-br/newsletter-31; https://lehacker.com/brain-facts-revealing/

  11. Can such finding be corroborated in behavioral responses, specifically in execution of movements? Random Source Images taken from https://www.lvhn.org/for_referring_physicians/better_medicine/rehabilitation/neuromuscular_rehabilitation_technology_helps_patients_i ncrease_motor_control; http://neuromat.numec.prp.usp.br/pt-br/newsletter-31; https://lehacker.com/brain-facts-revealing/

  12. Can such finding be corroborated in behavioral responses, specifically in execution of movements? Execution of Random movement Source Images taken from https://www.lvhn.org/for_referring_physicians/better_medicine/rehabilitation/neuromuscular_rehabilitation_technology_helps_patients_i ncrease_motor_control; http://neuromat.numec.prp.usp.br/pt-br/newsletter-31; https://lehacker.com/brain-facts-revealing/

  13. Can such finding be corroborated in behavioral responses, specifically in execution of movements? Rehabilitation of patients Execution of Random movement Source Goalkeeper Game Images taken from https://www.lvhn.org/for_referring_physicians/better_medicine/rehabilitation/neuromuscular_rehabilitation_technology_helps_patients_i ncrease_motor_control; http://neuromat.numec.prp.usp.br/pt-br/newsletter-31; https://lehacker.com/brain-facts-revealing/

  14. Stochastic processes driven by structured Markov chain o Finite alphabet 𝐡 o Sequence of stimuli π‘Œ π‘œ ∈ 𝐡 generated according to specific regular statistical pattern

  15. Stochastic processes driven by structured Markov chain o Finite alphabet 𝐡 o Sequence of stimuli π‘Œ π‘œ ∈ 𝐡 generated according to specific regular statistical pattern o Structured Markov chain π‘Œ π‘œ π‘œβˆˆβ„€ :

  16. Stochastic processes driven by structured Markov chain o Finite alphabet 𝐡 o Sequence of stimuli π‘Œ π‘œ ∈ 𝐡 generated according to specific regular statistical pattern o Structured Markov chain π‘Œ π‘œ π‘œβˆˆβ„€ : οƒ˜ for some π‘š , οƒ˜ any 𝑛 β‰₯ π‘š , ( π‘š, 𝑛 ∈ β„€ ) π‘œβˆ’1 = 𝑦 π‘œβˆ’π‘› , … , 𝑦 π‘œβˆ’1 ∈ 𝐡 𝑛 , οƒ˜ and any finite string 𝑦 π‘œβˆ’π‘› οƒ˜ : mapping assigning to each past string a corresponding class in a partition of the space of relevant pasts.

  17. Stochastic processes driven by structured Markov chain o Sequence of response 𝑍 π‘œ ∈ 𝒡 to the stimuli

  18. Stochastic processes driven by structured Markov chain o Sequence of response 𝑍 π‘œ ∈ 𝒡 to the stimuli o Stochastic processes driven by structured Markov chain

  19. Stochastic processes driven by structured Markov chain o Sequence of response 𝑍 π‘œ ∈ 𝒡 to the stimuli o Stochastic processes driven by structured Markov chain π‘Œ π‘œ π‘œβˆˆβ„€ is a structured Markov chain. οƒ˜ οƒ˜ 𝑍 1 , 𝑍 2 , … are independent variables conditionally to the sequence π‘Œ π‘œ π‘œβˆˆβ„€ for any measurable 𝐾

  20. Stochastic processes driven by structured Markov chain o Sequence of response 𝑍 π‘œ ∈ 𝒡 to the stimuli o Stochastic processes driven by structured Markov chain π‘Œ π‘œ π‘œβˆˆβ„€ is a structured Markov chain. οƒ˜ οƒ˜ 𝑍 1 , 𝑍 2 , … are independent variables conditionally to the sequence π‘Œ π‘œ π‘œβˆˆβ„€ for any measurable 𝐾 Stochastic processes driven by context tree model is an outstanding example of SPDSMC Related works: J.Garcia et al., arXiv:1002.0729 (2010); V. JÀÀskinen et al., Scand. J. Stat (2014)

  21. Prob1: Design of suitable experiments to evaluate evidence about learning statistical regularities

  22. Prob1: Design of suitable experiments to evaluate evidence about learning statistical regularities We need to carefully specify: o An alphabet 𝐡 o Response variable 𝑍 π‘œ

  23. Prob1: Design of suitable experiments to evaluate evidence about learning statistical regularities We need to carefully specify: o An alphabet 𝐡 o Response variable 𝑍 π‘œ Goalkeeper Game 0: center; 1: right; 2: left

  24. Prob1: Design of suitable experiments to evaluate evidence about learning statistical regularities We need to carefully specify: o An alphabet 𝐡 o Response variable 𝑍 π‘œ Goalkeeper Game 0: center; 1: right; 2: left 𝐸 π‘œ Curves of spatial position, Videos gathered by sensors or camera

  25. Prob1: Design of suitable experiments to evaluate evidence about learning statistical regularities We need to carefully specify: o An alphabet 𝐡 o Response variable 𝑍 π‘œ Goalkeeper Game 0: center; 1: right; 2: left 𝐸 π‘œ Curves of spatial position, Videos gathered by sensors or camera 𝑍 π‘œ ∈ 𝐡 direction

  26. Prob1: Design of suitable experiments to evaluate evidence about learning statistical regularities We need to carefully specify: o An alphabet 𝐡 o Response variable 𝑍 π‘œ Goalkeeper Game 0: center; 1: right; 2: left 𝐸 π‘œ Curves of spatial position, Videos gathered by sensors or camera 𝑍 π‘œ ∈ 𝐡 𝑍 π‘œ ∈ 𝒡 FD representing trajectory direction

  27. Prob1: Design of suitable experiments to evaluate evidence about learning statistical regularities We need to carefully specify: o An alphabet 𝐡 o Response variable 𝑍 π‘œ Goalkeeper Game 0: center; 1: right; 2: left 𝐸 π‘œ Curves of spatial position, Videos gathered by sensors or camera 𝑍 π‘œ ∈ 𝐡 𝑍 π‘œ ∈ 𝒡 𝑍 π‘œ ∈ 𝑍 = 0,1,2 Γ— *𝐻, 𝐢+ FD representing trajectory direction

  28. o Kind of statistical pattern of the stimuli sequence π‘Œ π‘œ π‘œβˆˆπ‘Ž Context tree model compatible with 𝜐, π‘ž ; π‘ž = π‘ž β‹… π‘₯ ∢ π‘₯ ∈ 𝜐

  29. o Kind of statistical pattern of the stimuli sequence π‘Œ π‘œ π‘œβˆˆπ‘Ž Context tree model compatible with 𝜐, π‘ž ; π‘ž = π‘ž β‹… π‘₯ ∢ π‘₯ ∈ 𝜐 π‘₯ 2 π‘₯ 3 π‘₯ 1 π‘₯ 4 𝑄 𝜐

  30. o Kind of statistical pattern of the stimuli sequence π‘Œ π‘œ π‘œβˆˆπ‘Ž Context tree model compatible with 𝜐, π‘ž ; π‘ž = π‘ž β‹… π‘₯ ∢ π‘₯ ∈ 𝜐 …….. 𝑏 …… π‘₯ 2 βˆ’π‘œ = 𝑦 βˆ’1 βˆ’π‘œ = 𝑄(π‘Œ 0 = 𝑏|𝑑 𝜐 (𝑦 βˆ’1 βˆ’π‘œ )) 𝑄 π‘Œ 0 = 𝑏|π‘Œ βˆ’1 π‘₯ 3 π‘₯ 1 π‘₯ 4 𝑄 𝜐

  31. o Kind of statistical pattern of the stimuli sequence π‘Œ π‘œ π‘œβˆˆπ‘Ž Context tree model compatible with 𝜐, π‘ž ; π‘ž = π‘ž β‹… π‘₯ ∢ π‘₯ ∈ 𝜐 …….. 𝑏 …… π‘₯ 2 βˆ’π‘œ = 𝑦 βˆ’1 βˆ’π‘œ = 𝑄(π‘Œ 0 = 𝑏|𝑑 𝜐 (𝑦 βˆ’1 βˆ’π‘œ )) 𝑄 π‘Œ 0 = 𝑏|π‘Œ βˆ’1 π‘₯ 3 π‘₯ 1 π‘₯ 4 𝑄 𝜐

  32. o Kind of statistical pattern of the stimuli sequence π‘Œ π‘œ π‘œβˆˆπ‘Ž Context tree model compatible with 𝜐, π‘ž ; π‘ž = π‘ž β‹… π‘₯ ∢ π‘₯ ∈ 𝜐 …….. 𝑏 …… π‘₯ 2 π‘₯ 3 π‘₯ 1 𝑄 π‘₯ 4 𝑑

  33. o Kind of statistical pattern of the stimuli sequence π‘Œ π‘œ π‘œβˆˆπ‘Ž Context tree model compatible with 𝜐, π‘ž ; π‘ž = π‘ž β‹… π‘₯ ∢ π‘₯ ∈ 𝜐 …….. 𝑏 …… π‘₯ 2 π‘₯ 3 π‘₯ 1 𝑄 π‘₯ 4 𝑑 The subject might adopt a form of representation of the given Markov chain that involves a certain partition into classes that does not involves a context tree

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