Crowdsourcing,Games,for, Biological,Research, Pravin,Muthu, - PowerPoint PPT Presentation

Crowdsourcing,Games,for, Biological,Research, Pravin,Muthu, Emory,University, June,13,,2013,

The,Kepler,Mission, Carter&Roberts&

The,CiFzen,ScienFst,

The,CiFzen,ScienFst, 18,894,075,ObservaFons,Analyzed, 34,PotenFal,Planets,Found, planethunters.org&

Crowdsourcing:,The,CollecFve,Expert,

LimitaFons,of,ComputaFonal,Methods,

LimitaFons,of,ComputaFonal,Methods,

Central,Dogma, DNA, RNA, Protein,

PHYLO:,The,DNA,Puzzle,

Genome,Alignment,

Sequence,Alignments:,Computer,Approach, Y A E L A H Q H W G G R W L V Q L M K D T L L K W L M F L N L I K E K P K Y I L Y& 7& Q& 51& 5& F& 3& 53& 6& A& 52& 51& 52& 4& L& 51& 52& 0& 51& 4& Y& Q& F& A& L& Existence:&11&Extension:&1&&

Sequence,Alignments:,Computer,Approach, Y A E L A H Q H W G G R W L V Q L M K D T L L K W L M F L N L I K E K P K Y I L

Sequence,Alignment:,Human,Solved, Y A E L A H Q H W G G R W L V L Q L M K D T L L K W L M Y L N L I K E K P K Y I L

Phylo:,The,DNA,Puzzle,

EteRNA:,The,RNA,Puzzle,

The,RNA,World, RNA, Ribosome, tRNA,

RNA,Modeling, tRNA, Ribosome,

RNA,Modeling, RNA,Modeling, tRNA, Ribosome, Mathis,et,al.,J.,Mol.,Biol.,(1999),288,,911±940,,

RNA,Folding,

RNA,Folding,

Let’s,Play,EteRNA!,

Foldit:,The,DNA,Puzzle,

Protein,Modeling,

Protein,Modeling, �

Research,Example,

Let’s,Play,Foldit!,

Final,Thoughts, Purpose& GamificaHon& SimulaHons& Gameplay& No&Gameplay& Gameful&Design& Games& Fun& Andrzej,Marczewski,