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Christo Christov Christo Z. . Christov MICHIGAN TECH RESEARCH - PowerPoint PPT Presentation

MICHIGAN TECH RESEARCH FORUM TECHTALKS Christo Christov Christo Z. . Christov MICHIGAN TECH RESEARCH FORUM christov@mtu.edu TECHTALKS Research / Scholarship Computational Biochemistry Reaction Mechanisms of Enzymes Dynamics of


  1. MICHIGAN TECH RESEARCH FORUM TECHTALKS Christo Christov

  2. Christo Z. . Christov MICHIGAN TECH RESEARCH FORUM christov@mtu.edu TECHTALKS Research / Scholarship • Computational Biochemistry • Reaction Mechanisms of Enzymes • Dynamics of Enzyme Substrate Complexes • Computational Design of Enzymes and Proteins

  3. Christo Z. Christov NAME, e-mail address christov@mtu.edu Scholarly Contributions • Histone Demethylation by Fe-containing Enzymes H319 A 2OG Fe 2+ H247 H3K9me2 D249 H319 - H3K9me2- 0.46 3.1Å B CH3 - 2.4 2OG 0.25 Å Fe-O 2.0Å Fe 3 Fe 2+ + 4.12 H247 D24 H247 9 H319 D249 H3K9me2

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