cell physiolgy
play

Cell Physiolgy By: Dr. Foadoddini Department of Physiology & - PowerPoint PPT Presentation

Sep 24, 2022 •695 likes •1.33k views

Cell Physiolgy By: Dr. Foadoddini Department of Physiology & Pharmacology Birjand University of Medical Sciences Dr. Foadoddini Functional Organization of the Human Body and Control of the "Internal Environment" Transport of

  1. Cell Physiolgy By: Dr. Foadoddini Department of Physiology & Pharmacology Birjand University of Medical Sciences ١ Dr. Foadoddini

  2. Functional Organization of the Human Body and Control of the "Internal Environment" Transport of Substances Through the Cell Membrane ٢ Dr. Foadoddini

  3. Control mechanisms: Negative Feed-back Positive Feed-back Feed-forward (Adaptation) ٣ Dr. Foadoddini

  4. ٤ Dr. Foadoddini

  5. ٥ Dr. Foadoddini

  6. ٦ Dr. Foadoddini

  7. ٧ Dr. Foadoddini

  8. ٨ Dr. Foadoddini

  9. ٩ Dr. Foadoddini

  10. ١٠ Dr. Foadoddini

  11. ١١ Dr. Foadoddini

  12. ١٢ Dr. Foadoddini

  13. ١٣ Dr. Foadoddini

  14. ١٤ Dr. Foadoddini

  15. ١٥ Dr. Foadoddini

  16. ١٦ Dr. Foadoddini

  17. ١٧ Dr. Foadoddini

  18. ١٨ Dr. Foadoddini

  19. ١٩ Dr. Foadoddini

  20. Membrane Resistance Conductance ٢٠ Dr. Foadoddini

  21. ٢١ Dr. Foadoddini

  22. ٢٢ Dr. Foadoddini

  23. ٢٣ Dr. Foadoddini

  24. ٢٤ Dr. Foadoddini

  25. ٢٥ Dr. Foadoddini

  26. Na + ‐ K + ATPase. 2 K+ Digitalin Digitalin P ATP ADP 3 Na+ ٢٦ Dr. Foadoddini

  27. ٢٧ Dr. Foadoddini

  28. ٢٨ Dr. Foadoddini

  29. ٢٩ Dr. Foadoddini

  30. Fick law: J = -DA dC/dx ٣٠ Dr. Foadoddini

  31. ٣١ Dr. Foadoddini

  32. ٣٢ Dr. Foadoddini

  33. ﻢﻴﺣﺮﻟا ﻦﻤﺣﺮﻟا ﷲا ﻢﺴﺑﻢﻴﺣﺮﻟا ﻦﻤﺣﺮﻟا ﷲا ﻢﺴﺑ Cell Physiolgy ٣٣ Dr. Foadoddini

  34. Membrane Potentials and Action Potentials ٣٤ Dr. Foadoddini

  35. ٣٥ Dr. Foadoddini

  36. ٣٦ Dr. Foadoddini

  37. ٣٧ Dr. Foadoddini

  38. ٣٨ Dr. Foadoddini

  39. E Na= +61 mV E K = -94 mV ٣٩ Dr. Foadoddini

  40. Goldman equation: ٤٠ Dr. Foadoddini

  41. ٤١ Dr. Foadoddini

  42. Self –Assessment (Bern) 1. With reference to the situation diagrammed below, which statement is true? A. CI- is in equilibrium. B. K+is in equilibrium. C. There is a net tendency for K+to diffuse C from B to A. D. Work is required to cause K+to flow from B to A. 2. In the "concentration cell" depicted below, the membrane is permeable to Cl- but completely impermeable to K+. Which statement is true? A. K+will diffuse from A to B. B. A potential difference EA- EB of +60 mV B will develop. C. Absolutely no Cl- will flow from A to B. D. Both K+and CI- will attain equilibrium . ٤٢ Dr. Foadoddini

  43. ٤٣ Dr. Foadoddini

  44. TTX TEA Dr. Foadoddini ٤٤

  45. ٤٥ Dr. Foadoddini

  46. ٤٦ Dr. Foadoddini

  47. ٤٧ Dr. Foadoddini

  48. Role of Ca Other onines ٤٨ Dr. Foadoddini

  49. Threshold / Firing level Stimulus: Types Amplitude Duration ٤٩ Dr. Foadoddini

  50. A Positive-feedback Vicious Cycle Opens the Sodium Channel Direction of impulse All –or- None Law ٥٠ Dr. Foadoddini

  51. Re-establishing Ionic Gradients After Action Potentials "recharging” of the nerve fiber is an active metabolic process Effect of excess sodium ions accumulate inside the cell membrane. ٥١ Dr. Foadoddini

  52. Importance of plateau Slow Ca-Na voltage channel Latency in K voltage channel ٥٢ Dr. Foadoddini

  53. REPETITIVE DISCHARGE Rhythmicity Cardiac m.: heart rate Smooth m.: peristalsis of the intestines CNS: neural event eg: control of breathing. Effect of Veratrine or low evel of Ca on N. or M. permeable enough to sodium ions or calcium to allow automatic membrane depolarization. "resting" membrane potential is only - 60 to -70 mV Hyperpolarization: for a short period thereafter, the membrane becomes excessively permeable to potassium ions ٥٣ Dr. Foadoddini

  54. ٥٤ Dr. Foadoddini

  55. sphingomyelin. is an excellent electrical insulator that decreases ion flow through the membrane about 5000-fold saltatory conduction. ٥٥ Dr. Foadoddini

  56. ٥٦ Dr. Foadoddini

  57. saltatory conduction increases the velocity of nerve transmission requiring little metabolism Repolarization to occur with very little transfer of ions ٥٧ Dr. Foadoddini

  58. ٥٨ Dr. Foadoddini

  59. Membrane stabilizing factors: Ca Local Anesthesia: procaine, tetracaine ٥٩ Dr. Foadoddini

  60. ٦٠ Dr. Foadoddini

  61. ٦١ Dr. Foadoddini

Recommend

Cell Physiolgy By: Dr. Foadoddini Department of Physiology & Pharmacology Birjand University

Cell Physiolgy By: Dr. Foadoddini Department of Physiology & Pharmacology Birjand University

Chapt. 6,7,8 Cell Physiolgy By: Dr. Foadoddini Department of Physiology & Pharmacology Birjand University of Medical Sciences Dr. Foadoddini Contraction of Skeletal Muscle Dr. Foadoddini Dr. Foadoddini Dr. Foadoddini T

831 views • 41 slides
Cell Communication and Cell Signaling Why is cell signaling important? Why is cell signaling

Cell Communication and Cell Signaling Why is cell signaling important? Why is cell signaling

Cell Communication and Cell Signaling Why is cell signaling important? Why is cell signaling important? Allows cells to communicate and coordinate functions/activities of the organism Usually involves the cell membrane Cell

408 views • 36 slides
What is single-cell RNA-Seq, and why is it useful? S IN GLE-CELL RN A-S EQ W ORK F LOW S IN R

What is single-cell RNA-Seq, and why is it useful? S IN GLE-CELL RN A-S EQ W ORK F LOW S IN R

What is single-cell RNA-Seq, and why is it useful? S IN GLE-CELL RN A-S EQ W ORK F LOW S IN R Fanny Perraudeau Senior Data Scientist, Whole Biome Milkshake or fruit salad?. SINGLE-CELL RNA-SEQ WORKFLOWS IN R scRNA-Seq could revolutionize

676 views • 25 slides
Cell Communication 4.1 and 4.3 Direct Contact What type of cell is this? Unit 4 Cell

Cell Communication 4.1 and 4.3 Direct Contact What type of cell is this? Unit 4 Cell

Cell Communication 4.1 and 4.3 Direct Contact What type of cell is this? Unit 4 Cell Communication What are the pores(openings) called? and Cell Cycle Mary Beth Cook Harrison County High School, Cynthiana KY Local Regulators- short

238 views • 5 slides
Bacteria Without a Cell Wall L-forms Pros & Cons of Cell Wall Cell membrane Cell wall DNA

Bacteria Without a Cell Wall L-forms Pros & Cons of Cell Wall Cell membrane Cell wall DNA

A New Chassis for Synthetic Biology: Bacteria Without a Cell Wall L-forms Pros & Cons of Cell Wall Cell membrane Cell wall DNA Cell membrane ribosomes RNA metabolites Bacterium with Bacterium cell wall without cell wall Previous

673 views • 35 slides
Cell Communication Topics 4.1 through 4.2 Topic 4.1 Cell Communication Importance of Cell

Cell Communication Topics 4.1 through 4.2 Topic 4.1 Cell Communication Importance of Cell

Cell Communication Topics 4.1 through 4.2 Topic 4.1 Cell Communication Importance of Cell Communication Cell signaling allows cells to communicate with one another and coordinate the functions/activities of the organism Communication

756 views • 48 slides
7/24/2016 Plasma (Cell) Membrane Cell membrane separates living cell from nonliving surroundings

7/24/2016 Plasma (Cell) Membrane Cell membrane separates living cell from nonliving surroundings

7/24/2016 Plasma (Cell) Membrane Cell membrane separates living cell from nonliving surroundings thin barrier = 8nm thick controls traffic in & out of the cell selectively permeable Chapter 7 allows some substances to cross

473 views • 7 slides
2. Cellular and Molecular Biology 2.1 Cell Structure 2.2 Transport Across Cell Membranes 2.3

2. Cellular and Molecular Biology 2.1 Cell Structure 2.2 Transport Across Cell Membranes 2.3

2. Cellular and Molecular Biology 2.1 Cell Structure 2.2 Transport Across Cell Membranes 2.3 Cellular Metabolism 2.4 DNA Replication 2.5 Cell Division 2.6 Biosynthesis 2.1 Cell Structure What is a cell? The smallest and most basic unit of

1.01k views • 68 slides
@newagemeats @nicklegendre Cell-cultured meat overview Cell-cultured meat -- also known as

@newagemeats @nicklegendre Cell-cultured meat overview Cell-cultured meat -- also known as

@newagemeats @nicklegendre Cell-cultured meat overview Cell-cultured meat -- also known as cell-based or lab-grown meat -- refers to meat created through cell culture and tissue engineering, without requiring animal slaughter. A small biopsy is

309 views • 15 slides
The ABCs of HLA: TCR Cell Beginners to Advanced CD4 IL2, IFN- Helper Rajalingam

The ABCs of HLA: TCR Cell Beginners to Advanced CD4 IL2, IFN- Helper Rajalingam

9/30/2016 Every cell expresses a HLA to present antigens to T lymphocytes In peripheral HLA class I Infection blood CD8 Perforine, Granzyme, Granulysin Cytotoxic T cell 23% The ABCs of HLA: TCR Cell Beginners to Advanced CD4 IL2,

436 views • 17 slides
Free Response Slide 2 / 6 1 Sketch a plant cell, an animal cell, and a bacterial cell. Label

Free Response Slide 2 / 6 1 Sketch a plant cell, an animal cell, and a bacterial cell. Label

Slide 1 / 6 Free Response Slide 2 / 6 1 Sketch a plant cell, an animal cell, and a bacterial cell. Label the organelles and other cellular structures. Slide 3 / 6 (top) A scanning electron micrograph of a red 2 blood cell with a pit on

243 views • 6 slides
Molecular Cell Biology (Bio 5068) Cell Cycle I Ron Bose, MD PhD November 14, 2017 CELL DIVISION

Molecular Cell Biology (Bio 5068) Cell Cycle I Ron Bose, MD PhD November 14, 2017 CELL DIVISION

Molecular Cell Biology (Bio 5068) Cell Cycle I Ron Bose, MD PhD November 14, 2017 CELL DIVISION CYCLE M G2 G1 S DISCOVERY AND NAMING OF CYCLINS A protein (called cyclin ) was observed to increase as cells approached mitosis, peak in

502 views • 37 slides
Molecular Cell Biology (Bio 5068) Cell Cycle I Ron Bose, MD PhD November 10, 2016 CELL DIVISION

Molecular Cell Biology (Bio 5068) Cell Cycle I Ron Bose, MD PhD November 10, 2016 CELL DIVISION

Molecular Cell Biology (Bio 5068) Cell Cycle I Ron Bose, MD PhD November 10, 2016 CELL DIVISION CYCLE M G2 G1 S DISCOVERY AND NAMING OF CYCLINS A protein (called cyclin ) was observed to increase as cells approached mitosis, peak in

585 views • 36 slides
Energy in the Cell In the cell, different structures and processes exist for the Production of

Energy in the Cell In the cell, different structures and processes exist for the Production of

Energy in the Cell In the cell, different structures and processes exist for the Production of Energy Storage of Energy Release of Energy Cells use energy for Homeostasis Movement and Feeding Cell Division Enzyme Production Cell organelles

329 views • 8 slides
Clustering methods for scRNA-Seq S IN GLE-CELL RN A-S EQ W ORK F LOW S IN R Fanny Perraudeau

Clustering methods for scRNA-Seq S IN GLE-CELL RN A-S EQ W ORK F LOW S IN R Fanny Perraudeau

Clustering methods for scRNA-Seq S IN GLE-CELL RN A-S EQ W ORK F LOW S IN R Fanny Perraudeau Senior Data Scientist, Whole Biome Mouse epithelium dataset 1 2 Cell Stem Cell, Fletcher et al, Deconstructing Olfactory Stem Cell Trajectories at

742 views • 19 slides
Comparative effect of Various HDAC-inhibitors in-vitro on T- Cell Lymphoma cell lines alone and

Comparative effect of Various HDAC-inhibitors in-vitro on T- Cell Lymphoma cell lines alone and

Comparative effect of Various HDAC-inhibitors in-vitro on T- Cell Lymphoma cell lines alone and in combination with conventional anti-cancer drugs Arshad H. Banday Mentor:Dr. Francisco Hernandez-Illizaliturri Introduction. T-cell lymphomas

744 views • 36 slides
Eukaryotic Cell Structures and Functions General Animal Cell Structure General Plant Cell

Eukaryotic Cell Structures and Functions General Animal Cell Structure General Plant Cell

Eukaryotic Cell Structures and Functions General Animal Cell Structure General Plant Cell Structure Plant Cells Animal Cells Cell Structures Plasma Membrane Surrounds the cell, selectively permeable Composed of a phospholipid

402 views • 26 slides
Energy in the Cell ATP= Most commonly used energy in the cell Adenosine triphosphate - Adenosine

Energy in the Cell ATP= Most commonly used energy in the cell Adenosine triphosphate - Adenosine

Energy in the Cell ATP= Most commonly used energy in the cell Adenosine triphosphate - Adenosine with 3 phosphate molecules attached Origins of ATP Mitochondria convert food energy (i.e. carbohydrates) to ATP A working muscle cell spends and

372 views • 19 slides
An Introduction to Cell Signaling: Outline 1. Question: How does the inside of a cell know

An Introduction to Cell Signaling: Outline 1. Question: How does the inside of a cell know

An Introduction to Cell Signaling: Outline 1. Question: How does the inside of a cell know something is happening on the outside of the cell? 1a. Receptors 1b. Plasma membrane 1c. Ligands 2. Answer: The inside of the cells knows

638 views • 53 slides
MP-ECBC CELL Lets build Tomorrow presentation by Kaushal Lodaya MP-ECBC CELL Member

MP-ECBC CELL Lets build Tomorrow presentation by Kaushal Lodaya MP-ECBC CELL Member

MP-ECBC CELL Lets build Tomorrow presentation by Kaushal Lodaya MP-ECBC CELL Member MP-ECBC CELL HOW TO DESIGN MP-ECBC COMPLIANT BUILDINGS MP-ECBC CELL BASIC DESIGN CONSIDERATION MP-ECBC CELL BUILDING Clients Requirement

1.19k views • 47 slides
Cell-Cell Communications Ron Weiss Department of Electrical Engineering Princeton University

Cell-Cell Communications Ron Weiss Department of Electrical Engineering Princeton University

Cell-Cell Communications Ron Weiss Department of Electrical Engineering Princeton University Computing Beyond Silicon Summer School, Caltech, Summer 2002 Programming Cell Communities Diffusing signal E. coli proteins Program cells to perform

609 views • 24 slides
ACTR (Antibody Coupled T-cell Receptor): A universal approach to T-cell therapy European

ACTR (Antibody Coupled T-cell Receptor): A universal approach to T-cell therapy European

ACTR (Antibody Coupled T-cell Receptor): A universal approach to T-cell therapy European Medicines Agency Workshop on Scientific and Regulatory Challenges of Genetically Modified Cell-based Cancer Immunotherapy Products 15-16 November 2016

359 views • 21 slides
Random Access Procedure UE picks one of the 64 RACH preambles available in an LTE cell. The

Random Access Procedure UE picks one of the 64 RACH preambles available in an LTE cell. The

Long Term Evolution (LTE) Attach and Default Bearer Setup (Moving from Old to New MME) Cell Sites LTE/SAE CN EventStudio System Designer 5 Cell New New EPC Old EPC Databases E-UTRAN 11-Dec-12 07:45 (Page 1) UE eNodeB New MME Serving

73 views • 6 slides
Spatiotemporal Cell Population Tracking & Cell Population Tracking and Lineage Construction

Spatiotemporal Cell Population Tracking & Cell Population Tracking and Lineage Construction

Spatiotemporal Cell Population Tracking & Cell Population Tracking and Lineage Construction Lineage Construction Kang Li , Takeo Kanade Carnegie Mellon University Mei Chen Intel Research Pittsburgh Cell Population Tracking Cell Population

357 views • 25 slides

More recommend