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Veterinary Vaccinology Network Early Career Vaccinologists Journal - PowerPoint PPT Presentation

Veterinary Vaccinology Network Early Career Vaccinologists Journal Club 08-05-15 Andrew Broadbent Codon bias Codon pair bias Influenza influenza Discussion Pros No phenotypic reversion to virulence DIVA vaccine Cons


  1. Veterinary Vaccinology Network Early Career Vaccinologists Journal Club 08-05-15 Andrew Broadbent

  2. Codon bias

  3. Codon pair bias

  4. Influenza

  5. influenza

  6. Discussion • Pros – No phenotypic reversion to virulence – DIVA vaccine • Cons – Shedding of mutant viruses and reassortment of mutant viruses with wt viruses might have unpredictable outcomes – Regulatory concerns for influenza

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