STRENGTHS OF THE DEPARTMENT (Established in 1991) Faculty members - PowerPoint PPT Presentation

STRENGTHS OF THE DEPARTMENT (Established in 1991) Faculty members are highly qualified with specialization in different core areas of Biotechnology Several Research Projects sanctioned by DBT, CSIR, DST, ICMR, DRDO, AICTE etc. Sanctioned DST-FIST grant of Rs. 1.10 Crores (2014-2019) Well equipped laboratories to impart training in different area of Biotechnology

Curricular Activities M. Sc. Biotechnology Ph.D. Program Through National Level Tests (CSIR-JRF, GATE etc.) and Admission through All Ph.D. Eligibility Test conducted by the University India Combined Entrance Achievements during Overseas Placements Examination (AICEE) Ph. D after Ph. D conducted by the JNU, New Delhi and GNDU  Nehru-Fulbright Doctoral  Ghent University, Belgium. entrance examination Scholarship - 2 (BELSPO fellowship) Students selected  Roslin Technologies, U.K.  DAAD Fellowship-1 through AICEE in  Max Planck Institute for  BINC Test (Bioinformatics Biotechnology are Developmental Biology, awarded a scholarship of National Certification)-1 Germany. Rs. 5,000 P.M. during  IBRO-APRC Fellowship-1  University of Manitoba, M.Sc. Biotechnology.  IBRO Travel Award-1 Canada. Majority of students  University of Illinois, qualify national level  ISN Travel Award-1 Chicago, USA. exams like  APSN Travel Award-1  University of Nebraska, NET/GATE/DBT-JRF test etc.  JNS Travel Award-1 USA.  Karolinska Institute, 74.46% of students get  AIST-Japan Fellowship-3 Sweden. placement in reputed  JST Travel Award-5 institutes for Ph.D  University of Notre Dame, program and absorbed in  Young Scientist Award-3 Australia. industry

Medical Biotechnology Plant Biotechnology Therapeutic potential applications of Deciphering strategies for abiotic glyco mimetics for spinal cord injuries. stress tolerance in plants. Scientific validation of natural products Biotechnological intervention in the for development of differentiation- improvement of medicinal plants . based therapy of brain diseases. Understanding the role of Glia in Health & Disease NICHE AREAS OF RESEARCH Structural and Computational Microbial Biotechnology Biology Characterization of cellulolytic Structural and functional studies of malarial drug targets. micorganisms

Research Projects S. Title Duration Funding Amt PI/ Co-PI No. Agency (Lacs) ONGOING RESEARCH PROJECTS 1 Neurocognitive correlates of childhood and 2020-2023 DST-CSRI 55.00 Prof. adolescent obesity: search for potential Gurcharan biomarkers and interventions. Kaur 2 Strategic induction of microglial cells to 2020-2023 ICMR, 45.00 Dr. Aditya develop early biomarkers and novel New Sunkaria molecular targets for Alzheimers disease – Delhi A secretome analysis. 3 Development of elite cultivars of Withania 2020-2022 RUSA, 15.00 Prof. P.K. somnifera and its Rapid Multiplication MHRD Pati Using Biotechnological Approaches 4 Exploring potential of Fractalkine binding 2020-2022 RUSA, 15.00 Dr. P.C. peptides for suppressing SLE MHRD Mishra 5 Identification and Characterization of Salt- 2019-2022 CSIR 27.00 Prof. induced Cyclophilins from a Stress Tolerant Prabhjeet Penicillium strain and their Implications in Singh Stress Tolerance

S. Title Duration Funding Amt PI/ Co-PI No. Agency (Lacs) 6 Elucidating the Mechanism of Interaction of 2019- DST- 49.8 Prof. Calmodulin with a Sorghum Glycine-Rich 2022 SERB Prabhjeet RNA-Binding Protein Singh 7 In vitro mass propagation of High value hill 2018- DBT 26.43 Prof. P.K. area Banana. (Multi-Institutional Project) 2021 Pati 8 Deciphering strategies for development of 2018- CSIR 37.00 Prof. P.K. leaf spot disease resistant Withania 2021 Pati somnifera (L.) Dunal. 9 Investigations of polysialic acid mimetics in 2017- DST 47.00 Prof. nervous system injury and disease 2020 Gurcharan Kaur COMPLETED RESEARCH PROJECTS 10 Study of molecular and cellular basis of 2015- DBT 40.00 Prof. obesity associated neuroinflammation and 2019 Gurcharan the role of natural products as Kaur neuroprotective agents 11 Behavioral and molecular study of 2015- DST 40.00 Prof. relationship between chronic sleep 2019 Gurcharan deprivation and cognitive impairments Kaur

S. Title Duration Funding Amt PI/ Co-PI No. Agency (Lacs) 12 Role of peptidyl prolyl cis-trans isomerases 2015- DBT 47.63 Prof. in acquisition of thermos tolerance in wheat 2018 Prabhjeet Singh 13 Sulforaphane mediated activation of protein 2015- DST-SERB 30.60 Dr. Aditya degradation machinery: A strategic approach 2018 Sunkaria against the pathogenesis of Alzheimer’s disease. 14 Development of In vitro Regeneration System 2015- DRDO 8.80 Prof. P.K. Pati (Cell suspension & Protoplast) and 2017 Comparative Analysis of Bioactive Compounds of Rhodiola Species, a High Value Medicinal Plant from Trans-Himalayan Region of Ladakh. 15 Structure-function analysis of plant NADPH 2014- DBT 58.50 Prof. P.K. Pati oxidase. 2018 16 Structure-function analysis of an exported 2013- DBT 43.64 Dr. P.C. parasite protein 2017 Mishra 17 Developing fungal strains for enzyme 2013- DBT 26.00 Prof. P.K. Pati production through mutagenesis, protoplast 2016 fusion and over-expression using A. niger citrate synthase promoter. (Multi-Institutional Project)

S. Title Duration Funding Amt PI/ Co-PI No. Agency (Lacs) 18 Heat Stress-Induced Calmodulin-Binding 2011- DBT 64.85 Prof. Proteins in Sorghum: Characterization, Cloning 2014 Prabhjeet and Expression Analysis Singh 19 Investigations on the therapeutic potential 2011- ICMR- 45.00 Prof. applications of PSA mimetics in cell culture 2014 BMBF Gurcharan and mouse models of brain injury and German Kaur disease y 20 Development of a Molecular Detection 2011- CSIR 21.70 Prof. P.K. System for Alternaria species infecting 2014 Pati Withania somnifera (L) and analysis of postinfectional changes during leaf spot disease using biochemical and molecular approaches. 21 Insight into 24-epibrassinolide mediated 2011- CSIR 20.00 Prof. P.K. synthesis of protective proteins and 2014 Pati enzymes in Brassica juncea L. under copper stress. 22 Structure-function studies on a conserved 2011- DBT 26.48 Dr. P.C. essential malaria parasite protein 2014 Mishra containing PEXEL motif

S. Title Duration Funding Amt PI/ Co-PI No. Agency (Lacs) 23 Use of Ashwagandha derived 2010- DBT 75.00 Prof. phytochemicals for development of 2014 Gurcharan differentiation-based therapy of brain Kaur cancers 24 Cellular and molecular mechanisms of 2010- DBT 59.00 Prof. adverse effects of antiepileptic and mood 2014 Gurcharan stabilizing drugs Kaur 25 Insights into secondary metabolite 2010- DBT 92.00 Prof. P.K. production and their accumulation in 2014 Pati Withania somnifera using in vitro propagation system. 26 Reproductive neuroendocrine dysfunction 2010- UGC 12.00 Prof. in cycling female rats treated with 2013 Gurcharan antiepileptic drugs Kaur 27 Brain Plasticity associated with cerebral 2010- DBT 25.26 Dr. P.C. malaria 2012 Mishra 28 Transgenic analysis for the role of wheat 2008- DBT 33.28 Prof. gene (TaVAP) encoding for a vesicle- 2011 Prabhjeet associated membrane protein-associated Singh protein in abiotic stress tolerance

S. Title Duratio Funding Amt PI/ Co-PI No. n Agency (Lacs) 29 Peptidyl prolyl cis trans isomerases Role in 2008- DBT 86.74 Prof. storage protein deposition in wheat and 2011 Prabhjeet relevance to industry Singh 30 Insights into brassinosteroids-regulated 2008- DST 28.00 Prof. P.K defense system of Raphanus sativus under 2011 Pati heavy metals stress using biochemical and molecular approaches. 31 Molecular and biochemical approaches to 2008- UGC 11.94 Prof. P.K study brassinosteroids mediated responses 2011 Pati in rice under pesticides and salt stress. 32 Juxtacrine and/or paracrine control of 2007- IFCPAR 78.00 Prof. Brain plasticity (From Indo-French Centre 2011 Gurcharan for promotion of advanced research) in Kaur collaboration with Dr. Vincent Prevot, INSERM, Lille, France 33 Reversing Age Related Brain Functions 2007- ICMR 30.00 Prof. Impairments by Late Onset Dietary 2011 Gurcharan Restriction Kaur

S. Title Duration Funding Amt PI/ Co-PI No. Agency (Lacs) 34 Neurogenesis in the Subventricular Zone 2006- ICMR 13.00 Prof. and Neocortex of Adult Rat: Interactive 2008 Gurcharan Effects of Excitotoxic Injury and Dietary Kaur Restriction 35 Purification and characterization of stress- 2005- DBT 32.72 Prof. induced calmodulin-binding proteins from 2010 Prabhjeet Sorghum Singh 36 Studies on correlation of drought-induced 2004- DBT 8.42 Prof. peptidyl prolyl cistrans isomerase activity 2006 Prabhjeet and drought tolerance in wheat Singh 37 Neuronal Plasticity in Adult brain: Study of 2002- DBT 24.00 Prof. molecular markers of synaptic remodeling 2005 Gurcharan in hypothalamic GnRH- astroglial cells Kaur 38 Identification cloning and characterization 2001- CSIR 17.98 Prof. of stress inducible genes in the grains of 2004 Prabhjeet wheat at different stages of development Singh 39 Molecular cloning and characterization of 2001- DBT 11.86 Prof. inulinase gene(s) from Aspergillus 2004 Prabhjeet fumigatus Singh