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Scientific Committee of the EFLM Elvar Theodorsson Tasks of the scientific committee Promotion of research that translates the scientific results of clinical chemistry and laboratory medicine to clinical applications and improves


  1. Scientific Committee of the EFLM Elvar Theodorsson

  2. Tasks of the scientific committee • Promotion of research that – translates the scientific results of clinical chemistry and laboratory medicine to clinical applications and – improves patient outcomes through the appropriate use and interpretation of laboratory data in clinical practice

  3. SC and EFLM strategic plan EFLM functio SECOND periodic status to be THIRD periodic status No Strategic nal FIRST periodic status to be sent by Activities sent by to be sent by objective unit(s) 5 JUNE 2014 15 SEPTEMBER 2014 6 NOVEMBER 2014 involve d 1. STRUCTURE AND ORGANIZATION 1 Develop Renewal of the MoU. EB, C- * WG-CM : A member of the IFCC WG WG-CM has noted that IFCC relationshi Liaison between Chairs Standardization of TnI has liaised the has a working group on cardiac ps and EFLM and IFCC survey of WG-Cm to US and Canada. markers. The IFCC working collaborati functional units of * S-C Chair now has direct contact group has its primary focus on on with mutual interest with Prof. Ian Young IFCC SD for educational matters. Paul IFCC mutual exchange of information . Collison is a liason between the IFCC and EFLM groups. 3 Standardiz Apply and maintain EB, * S-C chair and has made a particular Unchanged from the June report e EFLM the EFLM Procedure C/WG point of studying the EFLM Rules of operating Manual. Chairs Procedure in general and in the number procedures Implementing of more- or less delicate questions that guidelines for EFLM have needed attention meetings * WG-CM : Done 4 Review Ensure existing C, WG EB, * The functions of the WG and TFG The Science Committee chair activities of & TFG are fit for C/WG/T have been reviewed in this perspective. realizes this is an important Committee purpose and evaluate FG In the case of one TFG pointed out to challenge for him and intends to s (C), outcomes by Chairs the chair of the C-S by the EB, give this work high priority Working periodical reports and measures have been taken to speed up duting the autumn of 2014 groups at the end of the year the work towards finishing the task by (WG) and during the last EB agreed publication(s). A separate report Task and meeting on this matter was submitted to the EB Finish on June 3rd 2014. Groups * WG-CM : WG members are actively (TFG) involved in all activities.

  4. SC and EFLM strategic plan EFLM function SECOND periodic status to be THIRD periodic status to Strategic FIRST periodic status to be sent by No Activities al sent by be sent by objective 5 JUNE 2014 unit(s) 15 SEPTEMBER 2014 6 NOVEMBER 2014 involved 1. STRUCTURE AND ORGANIZATION 2. EFLM PROMOTION Participated in 7 EFLM Create an EFLM EB, C-C, WG-CM : List of publications on the w ebsite. Ensured that all publications issued Publications Publication Policy and WG-P, TFG-CR . Ensured that all publications issued have EFLM acknow ledged. maintain an updated C/WG have EFLM acknow ledged. Participated in initiating e-semninars inventory of EFLM Chairs arranged by the EFLM publications 14 Engagement Promote presence of EB, Cs, WG-CM : WG-CM members have given Sverre Sandberg and Elvar of EFLM EFLM representatives at WG-P presentations at their national meetings. Theodorsson w ill attend the semi- w ith NSs NS events. WG-TE : Tw o members of the WG-TE gave annual Nordic Conference in Clinical Promote the inclusion of talks at the April meeting of the Australasian Chemistry in Gothenburg in EFLM link on the w ebsite Association of Clinical Biochemists September. WG-CM has proposed of EFLM members. TFG-CR : Eva Ajzner and Rita Horvath have symposia for AACC and Promote a satisfaction had each their ow n oral presentation EuroMedLab Paris, but they have survey among EFLM NSs accepted for the AACC2014 congress in not been accepted. How ever, Paul Chicago this summer. Both on subjects Collison is giving lectures at related to critical results. Summaries of both WorldLab, AACC and EuroMedLab their talks w ill appear in the June 12th edition Paris. WG-PRE chair (Ana-Maria of CLN Stat, w hich is AACC's new w eekly e- Simundic) w as invited to ECAT new sletter. One or tw o manuscripts are being Symposium on Quality held on 14 prepared and are expected to be submitted May 2014 in den Hague (NL) to during 2014. present a lecture: Managing the quality of preanalytical phase, on behalf of EFLM WG-PRE.

  5. SC and EFLM strategic plan 3. RELATION WITH OTHER ORGANIZATIONS 17 Establish basis Identify potential partners. EB, C-S, * A memodandum of understanding has been written WG-PRE Has nominated Dr. Johannes for Exploring possibilities of WG-G with the European Atherosclerosis Society to Zander for the Walter Guder Preanalytical relationships cooperation and establish produce joint guidelies on the clinical use of Award WG-PRE is organizing the 3rd with clinical agreements measurements on plasma lipids and lipoproteins. EFLM-BD Preanalytical Phase meeting to organisations * EFLM was invided by the Swiss health authorities to be held in Porto (Portugal) during 20-21 participate in a working group to establish the use of March 2015. WG-PRE is organizing the biomarkers for Alzheimers disease . Patrick Bussuit 3rd EFLM-BD Preanalytical Phase meeting was appoiinted by the EFLM for this work. to be held in Porto (Portugal) during 20-21 * EFLM and UEMS have agreed on and signed a March 2015. WG-PLM has reached out to memorandum of understanding on co-operattion in The European Society of the working group on guidelines (WG-G). Pharmacogenomics and Therapeutics 1. Prepare guidelines for making recommendations (ESPT) for co-operation in applying for a for laboratory testing. Horizon 2020 grant for research in 2. Co-operate with clinical guidelines developers (e.g. personalised laboratory medicine. SIGN, ADA, NICE) for the development of the laboratory part of clinical guidelines. 3. Develop laboratory guidelines for reflective testing. * The president of the EFLM is working to identify a person able to formulate a project proposal to create a working group in the field of tumour markers * The EFLM Executive Board has identified the fields of Cardiology and Nephrology of particular relevence for co-operation with clinical disciplines * WG-CM : Has proposed joint symposia with ESC and IFCC for AACC 2014, ESC 2014, EuroMedLab 2015, no success, however.

  6. SC and EFLM strategic plan 4. SCIENTIFIC AFFAIRS 19 Ensure that Fulfil established ToR C-S * A lively dialog on this important topic is The analytical part of the meanigful and explore new taking place. measurement process is properly and potential areas (e.g. * Prof. Ferruccio Ceriotti has written and addressed by the principles and consequenti harmonization in submitted to the EB a proposal on methods of metrology. However al scientific Laboratory Medicine) "Harmonization of the total testing process". the majority of the remainder of the questions The harmonization should start from an total measurement process deals are homogeneous diagnostic approach to a with opinions, attitudes and identified as disease to continue with the correct preferences of people which are topics collection of the biological sample to be more properly addressed by analysed with a standardized method, qualitative research methods. reported with the correct units, interpreted Elvar Theodorsson and Ana-Maria versus adequate reference intervals and / Sigmundic are working on an or decision limits. If the entire process is opinion paper intended to stimulate optimally performed, the efficacy of dialog and discussion within the laboratory results on the patient’s outcome EFLM e.g. about the increased use will certainly improve. of qualitative methodologies in order to study the total testing process 20 Ensure that Surveillance by the C-S C-S, The matter of acknowledging EFLM has Ensured that all publications C-S Chair WGs been stressed within the C-S as a whole. issued have EFLM acknowledged. publications fully acknowledg e the contribution of EFLM in the authorship

  7. Working group Cardiac markers (WG-CM) • Results of survey 2013-2014, including US and Canada – Surveys 2009 and 2013 – Possibility to complement data – Manuscript will be drafted in the end of 2014 • Co-operation with IFCC – complementary work – The IFCC group is primarily educational – The EFLM group focuses on guidelines

  8. Working group Cardiac markers (WG-CM) • Co-operation with the EFLM WG Guidelines on a joint manuscript • Co-operation on symposia in international congresses • Website updates and new material

  9. Working group Biological Variation (WG-BV) • Identified further need for users to understand the uncertainty in applying published estimates of biological variation • Identify a minimum dataset to accompany published figures of biological variation • The WG-BV is establishing critical appraisal checklists for publication of biological variation data • Use of international coding system e.g. LOINC or SNOMED

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