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Prion diseases Mabbott et al. Nature Reviews Microbiology advance - PowerPoint PPT Presentation

Prion diseases Mabbott et al. Nature Reviews Microbiology advance online publication; published online 06 February 2006 | doi:10.1038/nrmicro1346 Infected brains CJD - human BSE - cow kuru - human BSE vCJD Infected animals Incidence of


  1. Prion diseases Mabbott et al. Nature Reviews Microbiology advance online publication; published online 06 February 2006 | doi:10.1038/nrmicro1346

  2. Infected brains CJD - human BSE - cow kuru - human

  3. BSE  vCJD Infected animals Incidence of entering food supply vCJD

  4. Structure of PrP

  5. PrP c PrP Sc

  6. Models for conversion from PrP c to PrP Sc

  7. Seeding models of prion propagation

  8. Mutations in Prnp associated with human TSEs

  9. Role of cytoplasmic PrP in neurodegenerative disease

  10. Lee et al., 2000

  11. Olsson et al., 1995

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