Preliminary data show 938 confirmed and estimated opioid-related - PowerPoint PPT Presentation

Preliminary data show 938 confirmed and estimated opioid-related overdose deaths within the first six months of 2019 Figure 1. Opioid-Related Overdose Deaths, All Intents by Month Massachusetts Residents: January 2018 - June 2019 Confirmed Estimated 250 200 Number of deaths 2 4 3 2 12 4 3 1 150 7 1 4 1 4 2 10 41 100 193 119 182 181 179 165 167 166 162 163 160 155 152 149 146 144 137 108 50 40 1 0 Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun 2018 2019 Estimated 938 deaths Estimated 1,050 deaths

The rate of opioid-related overdose deaths decreased for a second straight year – for a total of an estimated 4% decrease from 2016 to 2018. Figure 3. Rate of Confirmed and Estimated Opioid-Related Overdose Deaths, All Intents Massachusetts Residents: 2000 - 2018 35 30.5 29.7 21% 29.4 30 per 100,000 Residents -3% 25.2 -1% 27% 25 Rate 40% 20 19.9 14.2 15 9.9 9.6 9.9 8.8 9.6 10 7.9 11.0 10.2 9.6 8.0 8.2 7.9 5 5.9 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018

Fentanyl remains a key factor in opioid-related overdose deaths (92% present in toxicology screen) but we’re also seeing a rise in the presence of amphetamines. Figure 4. Percent of Opioid-Related Overdose Deaths with Specific Drugs Present Massachusetts Residents: 2014 - Q1 2019 100 90 80 Fentanyl¹ 70 Likely Heroin 60 Percent Prescription Opioid² 50 Benzodiazepine 40 Cocaine 30 Amphetamine 20 10 0 1 2 3 4 1 2 3 4 1 2 3 4 1 2 3 4 1 2 3 4 1 2014 2015 2016 2017 2018 2019 Year and Quarter

Prescription Monitoring Program – Data Trends Figure 1. Schedule II Opioid Prescriptions and MassPAT 1 Search Activity 2 Trends MA: Q1-2015 - Q2 2019 2,500,000 900,000 850,000 2,000,000 800,000 Number of Prescriptions Number of Searches 750,000 1,500,000 700,000 1,000,000 650,000 Mass PAT GoLive 600,000 Aug 22, 2016 500,000 Mar 15, 2016 4 Oct 15, 2016 5 550,000 Dec 7, 2015 3 0 500,000 1 2 3 4 1 2 3 4 1 2 3 4 1 2 3 4 1 2 2015 2016 2017 2018 2019 Total Schedule II Opioid Prescriptions Number of Searches by Prescribers and Pharmacists 1 MassPAT is the Massachusetts Prescription Awareness Tool (Online PMP) 2 Search activity includes prescribers, delegates, and pharmacists registered in MassPAT (and in the previous Online system) and licensed users of EHR Integration 3 Pharmacies required to report daily 4 STEP bill signed into law (7-day supply requirements go into effect) 5 MA prescribers required to look up patient when prescribing a Schedule II or III opioid medication • Registered MassPAT providers conducted more than 2 million searches in the 2 nd quarter of 2019, an increase of approximately 200,000 searches since the previous quarter. • There were just over 515,000 Schedule II opioid prescriptions reported to the MA PMP in the 2 nd quarter of 2019; this is a small decrease from the previous quarter and a 39% decrease from the 1st Quarter of 2015. • In the 2 nd quarter of 2019, just over 236,000 individuals in Massachusetts received prescriptions for Schedule II opioids; this is a small, but notable, decrease from the previous quarter and nearly a 40% decrease from the 1 st quarter of 2015.

Between 2007 and 2018, over 81,000 people enrolled in Overdose Education and Naloxone Distribution Programs (OEND), were trained in overdose prevention, and equipped with naloxone rescue kits. Figure 1: DPH OEND Program Enrollments by Year, 2007-2018 16,000 14,102 14,000 13,107 12,000 11,106 10,855 Non-User 10,242 6,386 5,202 10,000 Enrollments People who use drugs 4,656 4,696 3,930 8,000 5,439 6,000 4,343 3,923 3,818 1,750 4,000 7,905 7,716 1,481 2,415 1,335 6,450 1,279 6,312 6,159 1,980 298 2,000 768 3,689 50 707 2,862 2,588 2,539 248 1,647 1,273 0 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 Year Total Program Enrollments: 81,630 Total User Enrollments: 49,386 Total Non-User Enrollments: 32,244

Over 16,000 rescues were reported by bystanders who administered naloxone to a person who was overdosing. Figure 2: DPH OEND Program Rescues by Year, 2007-2018 4,500 4,079 4,000 451 3,487 3,500 389 Non-User 2,939 3,000 377 People who use drugs 2,500 Rescues 2,124 2,000 225 3,628 1,437 3,098 1,500 161 2,562 1,000 720 1,899 61 458 436 1,276 295 282 46 52 500 222 40 26 16 659 412 384 255 256 206 0 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 Year Total Rescues: 16,480 Total Rescues by Users: 14,636 Total Rescues by Non-users: 1,844