P15611: Microfluidics Packing Problem Definition Review Agenda - PowerPoint PPT Presentation

P15611: Microfluidics Packing Problem Definition Review

Agenda ● Introduce Team ● Background ● Problem Statement ● Use Scenarios ● Customer & Engineering Requirement ● Project Plan ● Issues and Risks

Team Introduction Ilmar Begishev Project Manager (ME) Clair Cunningham Co-Lead Engineer (ME) Angel Rosario Ortiz Co-Lead Engineer (ME) Alex Ryan Bio-Engineering Specialist (BME) Brody Smith Design Engineer (ME)

Project Background - Microfluidics ● Electrodes manipulate droplets ● Does not need channels, pumps, or valves ● Ultimate goal: Lab-on-a-Chip (LOAC) ● Useful for molecular diagnostics

Project Background - ELISA ● Enzyme-Linked Immunosorbent Assay ● Diagnostic Tool using antibody specificity ● Numerous Healthcare applications ● Labor Intensive ● Requires Wetlab

Existing Device ● Microfluidics lab Digital Microfluidics (DMF) chip ● Tests occur on a double microscope slide ● Pogo pins to make electrical contacts ● Lacks Environmental Control ● Exposed Chip

Problem Statement The goal is to create an enclosure that can deliver fluid and provide a controlled environment for the DMF device. ● Must allow easy camera and microscope access. ● The enclosure must allow for electrical connections to the chip. ● Should allow for environmental control and monitoring to maintain droplet size. ● Must adhere to electrical safety and cleanliness standards. ● Should allow for easy access to chip between tests.

Deliverables ● Chip Enclosure ○ Allows Access with Microscope or Camera ○ Allows for Fluid Delivery to the Chip ○ Modular Design ● Environmental Monitoring ○ Real Time & Recorded Measurements ● Environmental Control ○ Humidity or Refrigeration

Use Scenarios ● Current ○ Imagine RIT interactive event ○ Laboratory/Research Tool ● Future ○ Device can be used for lab tests in: Hospitals ■ Remote locations ■

Stakeholders ● Customer: Dr. Michael Schertzer ● Microfluidics Lab ● MSD Team 15611 ● MSD Team 15610 ● Project Guide: Michael Zona

Customer Requirements

Engineering Requirements

House of Quality

Benchmarking Benchmarking was taken from much larger devices and will be scaled down.

Project Plan

Risk Management Concerns ● Microscope Compatibility ● Condensation ● Communication with Team P15610 ● Maintaining Chip Cleanliness ● Time & Budget Management ● Defective Parts ● Team Disagreements

Questions? P15611: Digital Microfluidics Packaging