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Overview of Cancer Prevention and Research Institute of Texas (CPRIT) Funding (CPRIT) Funding H O U S E AP P R O P R I ATI O N S CO M M I TTE E P R E P AR E D B Y TH E LE GI S LATI V E B U D GE T B O AR D D E CE M B E R 2 0 , 2 0 12


  1. Overview of Cancer Prevention and Research Institute of Texas (CPRIT) Funding (CPRIT) Funding H O U S E AP P R O P R I ATI O N S CO M M I TTE E P R E P AR E D B Y TH E LE GI S LATI V E B U D GE T B O AR D D E CE M B E R 2 0 , 2 0 12

  2. Establishment and Creation of CPRIT  CPRIT was established with the passage and CPRIT bli h d i h h d ratification by voters of a constitutional amendment in November 2007 (House Joint Resolution 90, Ei h i Eightieth Legislature, 2007); h L i l )  CPRIT is the successor agency to the Cancer Council; CPRIT is the successor agency to the Cancer Council;  Amendment authorized $3 billion in general obligation bonds to fund grants for cancer prevention bli ti b d t f d t f ti and research, and agency operations; Legislative Budget Board ID: 748 December 20, 2012 Page 2

  3. Article III, Section 67 & Health and Safety Code 102 y  Amendment also limits issuance of bonds, by the Texas Public Finance Authority on behalf of CPRIT to Texas Public Finance Authority on behalf of CPRIT, to no more than $300 million per fiscal year;  CPRIT is governed by the Constitution & Statute:  Art. III, Sec. 67 of the Texas Constitution includes the original amendment creating the agency and authorizing bond issuance.  Health and Safety Code 102, CPRIT’s enabling statute (HB 14, 80 th Legislature) provides:  Sunset date of September 2021; p ;  Limits the amount of awards for prevention grants to 10 percent in any given fiscal year; and  Establishes the Oversight Committee as CPRIT’s governing body. Legislative Budget Board ID: 748 December 20, 2012 Page 3

  4. Oversight Committee  CPRIT is governed by an Oversight Committee which consists of 11 members composed of three appointees each from the Governor, Lieutenant Governor, and Speaker of the House of Representatives. Additionally, both the Comptroller and Attorney General, or their respective designees, are members of the Oversight Committee.  Each appointee serves staggered six-year terms and may include cancer survivors and family members of cancer patients. Legislative Budget Board ID: 748 December 20, 2012 Page 4

  5. Appropriations  House Bill 1, Eightieth Legislature, 2007, provided $6.6 million in General Revenue Related Funds for the 2008-09 biennium for the Cancer Council, contingent on the passage of a constitutional amendment be renamed the Cancer of a constitutional amendment be renamed the Cancer Prevention and Research Institute of Texas; and  House Bill 4586, Eighty-first Legislature, 2009, appropriated $0.9 million out of General Revenue for operations of the Cancer Prevention and Research Institute operations of the Cancer Prevention and Research Institute for fiscal years 2009, 2010 and 2011. Legislative Budget Board ID: 748 December 20, 2012 Page 5

  6. Appropriations and Expenditures 2010-11 Biennium Senate Bill 1, 81 st Legislature, 2009, appropriated $450 million in General Obligation Bond Proceeds to CPRIT for the 2010-11 biennium. Award Cancer Award Cancer Direct and Research Grants Prevention Indirect Grants* Adm inistration Appropriated $389,180,850 $43,492,650 $15,493,500 Expended $386,756,521 $43,550,251 $18,116,960 Amount Over/ (Under) ($2,424,329) $57,601 $2,623,460 Source: Legislative Budget Board and Cancer Prevention and Research Institute of Texas Note: Article IX, Section 14.01 Transfer Authority, of the 2010-11 General Appropriations Act, provides an agency to transfer up to 12.5 percent from one Item of Appropriation to another Item of Appropriation. *N t i *Not included is $42,000 out of General Revenue Dedicated - Cancer Prevention and Research Fund No. 5136 for l d d i $42 000 t f G l R D di t d C P ti d R h F d N 5136 f prevention grants. Legislative Budget Board ID: 748 December 20, 2012 Page 6

  7. Appropriations and Expenditures 2012-13 Biennium 3 House Bill 1, 82 nd Legislature, 2011, appropriated $600 million in General Obligation Bond Proceeds to CPRIT for the 2012-13 Biennium. g Award Cancer Award Cancer Grant Review Indirect Research Prevention and Award Adm inistration Grants Grants* Operations** p Appropriated $516,382,196 $58,037,134 $12,888,718 $5,816,844 Expended/ E d d/ Budgeted $504,388,007 $58,038,340 $24,217,153 $7,507,770 Amount Over/ (Under) ($11,994,189) $1,206 $11,328,435 $1,690,926 Source: Legislative Budget Board and Cancer Prevention and Research Institute of Texas Note: Article IX, Section 14.01 Transfer Authority, 2012-13 General Appropriations Act, allows agencies to transfer up to 20 percent from one Item of Appropriation into another Item of Appropriation. *Not included is $24,000 out of General Revenue Dedicated - Cancer Prevention and Research Fund No. 5136 for prevention grants prevention grants. **Not included is $40,000 out of Appropriated Receipts for fees paid by commercialization grant applicants for additional costs associated with the commercialization review Legislative Budget Board ID: 748 December 20, 2012 Page 7

  8. Appropriations and Expenditures Total for 2010 11 and 2012 13 Biennia Total for 2010-11 and 2012-13 Biennia Award Cancer Award Cancer Direct and Research Grants Research Grants Prevention Prevention Indirect Indirect Grants* Adm inistration** Appropriated Appropriated $905 563 046 $905,563,046 $101,529,784 $101 529 784 $34,199,062 $34 199 062 Expended $891,144,528 $101,588,591 $49,841,883 Amount Over/ (Under) ($14,418,518) $58,807 $15,642,821 Source: Legislative Budget Board and Cancer Prevention and Research Institute of Texas Note: Article IX, Section 14.01 Transfer Authority, of the 2010-11 General Appropriations Act, provides an agency to transfer up to 12.5 percent from one Item of Appropriation to another Item of Appropriation and Article IX, Section 14.01 Transfer Authority, 2012-13 General Appropriations Act, allows agencies to transfer up to 20 percent from one Item of Appropriation into another Item of Appropriation. *Not included is $62,000 out of General Revenue Dedicated - Cancer Prevention and Research Fund No. 5136 for prevention grants. **Not included is $40,000 out of Appropriated Receipts for fees paid by commercialization grant applicants for additional costs associated with the commercialization review Legislative Budget Board ID: 748 December 20, 2012 Page 8

  9. CPRIT’s Expenditures (In Millions) 20 10 -11 Expended 20 12-13 Estim ated/ Budgeted $58.0 $43.5 $18.1 $31.7 $504.4 $386.0 FTEs: 20.5 FTEs: 24.0 Cancer Research Grants Cancer Research Grants Cancer Prevention Grants Cancer Prevention Grants Grant Review and Indirect Administration Grant Review and Indirect Administration Source: Legislative Budget Board and Cancer Prevention and Research Institute of Texas Legislative Budget Board ID: 748 December 20, 2012 Page 9

  10. CPRIT Grant Programs • CPRIT has awarded approximately $840.8 million in grant awards, and expects to award an additional $151 9 million through the end of and expects to award an additional $151.9 million through the end of fiscal year 2013, in 3 categories: • Research • Research - grants for basic science to translational research and grants for basic science to translational research and clinical applications. These grants range from short-term projects to multi-year research programs at laboratories and research facilities throughout the state; throughout the state; • Prevention- grants that target projects and new partnerships, that increase the availability of screening services provided and detection increase the availability of screening services provided and detection of cancer, to increase survival rates; and • Commercialization • Commercialization - grants focus on the commercialization of cancer grants focus on the commercialization of cancer detection, drugs and devices that demonstrate significant potential. Legislative Budget Board ID: 748 Page 10 December 20, 2012

  11. Total CPRIT Grant Awards By Type As of December 5, 2012 Commercialization Commercialization $95.9 million 11.4% Prevention o $85.9 million 10.2% Total Grant Awards $840.8 million Research $659.0 million 78.4% 78.4% Total General T l G l Obligation Bond Proceeds Appropriated for Grants $1,007.1 million $1,007.1 million Source: Cancer Prevention and Research Source: Cancer Prevention and Research Institute of Texas Legislative Budget Board ID: 748 December 20, 2012 Page 11

  12. Appropriations of Bond Proceeds and Bond Issuances and Bond Issuances 20 10 20 11* 20 10 -11 Biennial Total Total Appropriated $225,000,000 $225,000,000 $450,000,000 Issued Issued 225 000 000 225,000,000 $62 575 000 $62,575,000 $287 575 000** $287,575,000** *House Bill 2251, 82 nd Legislature, 2011, removed the escrow requirement and allows the Texas Public Finance Authority to issue the CPRIT bonds as needed for expenditure. 20 12 20 13 20 12-13 (thru Decem ber 20 12) Biennial Total Appropriated $300,000,000 $300,000,000 $600,000,000 Issued 75,700,000 $9,600,000 $85,300,000** Source: Legislative Budget Board and Texas Public Finance Authority **As of December 14, 2012, approximately $677,125,000 in Bond Proceeds appropriated to CPRIT during the 2010-11 and 2012-13 biennia remain unissued. Legislative Budget Board ID: 748 December 20, 2012 Page 12

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