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How Telehealth Can Improve Patient Care and Outcomes: Mobile Health (mHealth) vs Clinic-Based Intervention for People with Serious Mental Illness Discussant: Mark Ishaug, MA Speaker: Dror Ben-Zeev, PhD CEO, Thresholds Professor of Psychiatry


  1. How Telehealth Can Improve Patient Care and Outcomes: Mobile Health (mHealth) vs Clinic-Based Intervention for People with Serious Mental Illness Discussant: Mark Ishaug, MA Speaker: Dror Ben-Zeev, PhD CEO, Thresholds Professor of Psychiatry and Behavioral Sciences, University of Washington Director, mHealth for Mental Health Program #PCORI2018 November 1, 2018

  2. Dror Ben-Zeev, PhD • Disclosure: Intervention content licensing agreement with Pear Therapeutics Mark Ishaug, MA Disclosure: Nothing to disclose 2 • November 1, 2018

  3. Serious Mental Illness (SMI) • Schizophrenia, Bipolar Disorder, Major Depressive Disorder • 4% of world population • Significant functional impairment • May be chronic but certainly not static • Illness management strategies increase and lengthen recovery periods 3 • November 1, 2018

  4. Barriers of Clinic-Based Mental Health Care • Distance/transportation • Hours of operation • Other patients/people • Stigma • Quality of care 4 • November 1, 2018

  5. Mobile Health (mHealth) for Mental Health • Mobile phones are ubiquitous (Ben-Zeev et al., 2012; Carras et al., 2014; Torous, 2018) • People with SMI are interested in mHealth (Firth et al., 2015) • Smartphones can bring mHealth to life • mHealth for SMI shows promise How does mHealth compare to clinic-based care? 5 • November 1, 2018

  6. FOCUS: mHealth Intervention for people with SMI • 3 Daily prompts • “On-demand” resources Hello, Drori! • 5 treatment targets: voices, social, MEDICATION VOICES meds, sleep, mood MOOD SOCIAL • Dashboard • mHealth Support Specialist SLEEP TOOLBOX 6 • November 1, 2018

  7. FOCUS interactions • System prompt: 3 times daily • Patient initiated: On demand 24/7 • mHealth specialist: 1 phone call weekly 7 • November 1, 2018

  8. FOCUS Clinical Status Assessment Hello, Rachel! Have you been bothered by voices today? 8 • November 1, 2018

  9. FOCUS Cognitive Assessment How would you describe the voices: 9 • November 1, 2018

  10. FOCUS Intervention: Written If the voices got it wrong once, they probably don’t know Voices may sound like they How about when the voices Can you think of any time when everything, right? Think about know everything, but they were sure something was the voices made a mistake? it. don’t. going to happen, but it didn’t? 10 • November 1, 2018

  11. FOCUS Intervention: Videos 11 • November 1, 2018

  12. FOCUS Online Dashboard 12 • November 1, 2018

  13. PCORI-funded comparative effectiveness trial: 2015- 2017 • Study site: Thresholds Chicago • Randomized Controlled Trial (RCT) • N=163 (49% schizophrenia, 28% bipolar disorder, 23% MDD) • 18 years or older (Average age: 49) • Ethnicity: 65% African-American, 27.5% White • Fifth grade reading level or higher • Assessments: Baseline (0 months) Post treatment (3 months) Follow Up (6 months) Ben-Zeev et al. (2018) Psychiatric Services. 13 • November 1, 2018

  14. Comparative Effectiveness Trial (12 Week RCT) FOCUS (N=82) WRAP (N=81) Hello, Peter! MEDICATION VOICES vs MOOD SOCIAL SLEEP TOOLBOX No Significant Difference in Clinical Outcomes or Satisfaction Ratings Between Conditions Ben-Zeev et al. (2018) Psychiatric Services. 14 • November 1, 2018

  15. Study Results: Treatment Commencement and Patient Engagement Ben-Zeev et al. (2018) Psychiatric Services. 15 • November 1, 2018

  16. Study Results: Depression Ben-Zeev et al. (2018) Psychiatric Services. 16 • November 1, 2018

  17. Study Results: General Psychopathology Ben-Zeev et al. (2018) Psychiatric Services. 17 • November 1, 2018

  18. Study Results: Recovery Ben-Zeev et al. (2018) Psychiatric Services. 18 • November 1, 2018

  19. Study Results: Patient Satisfaction Ben-Zeev et al. (2018) Psychiatric Services. 19 • November 1, 2018

  20. Conclusion and Next Steps • mHealth demonstrated superior treatment commencement and engagement • FOCUS and WRAP produced similar patient satisfaction and clinical outcomes • How do we disseminate and implement mHealth in real-world mental health treatment settings? • FCC’s Lifeline program? • Billing Codes for mHealth related activities? Ben-Zeev et al. (2018) Psychiatric Services. 20 • November 1, 2018

  21. Learn More • www.pcori.org/research-results/2014/comparing-smartphone- program-peer-led-program-help-people-serious- mentalinfo@pcori.org • #PCORI2018 • www.mhh4mh.org • Ben-Zeev, D., Brian, R.M., Jonathan, G.K., et al. (2018). Mobile Health (mHealth) vs Clinic-Based Group Intervention for People with Serious Mental Illness: A Randomized Controlled Trial. Psychiatric Services 69 (9), 978-985. https://ps.psychiatryonline.org/doi/10.1176/appi.ps.201800063 21 • November 1, 2018

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