IN THE NAME OF GOD
PERSISTENCE AND CLEARANCE COVID19 By Dr Davoud Esmaeili Fellowship in Clinical Laboratory Sciences
Attachment ACE2 NANA CD13 SPIKE HE Fc IgG NANA Tight att.
Persistent COVID-19 ◦ incubation period ◦ Strong Attachment ◦ Enveloped ◦ Budding ◦ PH
ACE2 Receptors in TUBULE
Immunohistochemistry analyzed SARS- CoV-2 NP antigen in kidney tissues Tubular arrow indicated NP positive tubules and arrow head indicated viral inclusion body
COVID19& Tubule Receptor
Immunohistochemistry analyzed lymphocytes and the complement C5b9 in kidney tissues. The expression of (A) CD68, CD8 and CD56; (B) C5b-9 in kidney tissues from COVID-19 patients
Lymphocyte & Macrophage Infiltration
COVID19 & Golgi, ER
Cytokine Storm Sepsis Immune Complex Hyper coagulopathy Hypertension Hypotension Ren-Ang-Ald
Clearance Immune Response
IMMUNITY to COVID19
Kidney
Immunity double-edged sword
Clearance Drug
COVID-19 Persistent in Kidney? COVID-19 Clearance? Drugs? COVID19 Prevention? Disinfectant?
Thank you for your attention
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