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Improving Healthcare Quality and Safety While Reducing Costs Through Clinical Pharmacy Service Integration Michael Hochman, MD, MPH Medical Director for Innovation AltaMed Health Services Steven W. Chen PharmD, FASHP , FCSHP , FNAP


  1. Improving Healthcare Quality and Safety While Reducing Costs Through Clinical Pharmacy Service Integration Michael Hochman, MD, MPH Medical Director for Innovation AltaMed Health Services Steven W. Chen PharmD, FASHP , FCSHP , FNAP Associate Professor and Chair Titus Family Department of Clinical Pharmacy and Pharmacoeconomics and Policy Hygeia Centennial Chair in Clinical Pharmacy Co-Chair Emeritus, HRSA Patient Safety & Clinical Pharmacy Services Collaborative Edith Mirzaian, PharmD, BCACP Assistant Professor, Clinical Pharmacy & Pharmaceutical Economics and Policy Director, USC Telehealth Medication Therapy Management Program

  2. Questions to Run on… • What are some successes your organization has had in improving medication-related quality and safety for patients at risk for cardiovascular disease? • How can your organization adapt the approaches shared to provide optimal medication therapy outcomes for your patients? • What barriers prevent your organization from integrating clinical pharmacy services?

  3. Outline • Overview of the USC / AltaMed Healthcare Innovation Award (HCIA) program from CMMI • Early results from the HCIA program • Medical leadership perspective • Patient perspective • Stepwise process for implementation • USC Telehealth MTM program

  4. Medication Safety Problems in U.S. • 1.5 million people are injured each year due to medications • ~25% of ambulatory patients experience adverse drug events • 90% of chronic diseases require medications as first-line therapy • “…for every dollar spent on ambulatory medications, another dollar is spent to treat new health problems caused by the medication.” Institute of Medicine (IOM), To Err Is Human: Building a Safer Health System, Washington, DC: National Academy Press; 2000.

  5. USC Personnel: Geoffrey Joyce, PhD- CoPI Steven Chen, PharmD Kathleen Johnson, PhD, PharmD R. Pete Vanderveen, Ph.D.

  6. USC / AltaMed CMMI Project: Specific Aims Resident and Telehealth clinical 10 teams technician training pharmacy Pharmacist + Resident + for expansion Clinical Pharmacy Technician OUTCOME MEASURES  Healthcare Quality UNIVERSITY OF  Safety SOUTHERN CALIFORNIA  Total Cost / ROI National Conference on Best  Patient & provider Practices and Collaborations to Improve Medication Safety and satisfaction Healthcare Quality Web-based pharmacist training  Patient access and credentialing Feb 20-21, 2014

  7. USC Patient Targeting and Management Strategy Comprehensive Medication High cost patients Management Treatment Goal Reached? Frequent and recent Clinical Pharmacy acute care utilizers No Yes 48 EHR-embedded triggers to detect high risk patients Clinical pharmacy Unstable tech “check - ins” every 2 months MD referrals

  8. Outline • Overview of the USC / AltaMed Healthcare Innovation Award (HCIA) program from CMMI • Early results from the HCIA program

  9. Outcome: Recruit high risk patients • Enrolled 6,000 patients since Oct 2012 • Predominantly Hispanic, non-elderly women • 3/4 ths have hypertension, 36% uncontrolled • 2/3 rds have diabetes, 60% uncontrolled • High rates of hospitalizations

  10. Outcome: Improvement in Clinical Markers Systolic Blood Pressure Diastolic Blood Pressure 155 88 86 150 84 145 82 80 140 78 135 76 130 74 72 125 Baseline 3 Months Most Baseline 3 Months Most Recent Recent * Among those with uncontrolled hypertension at baseline

  11. What blood pressure level should be targeted for most patients under the age of 60? A. 130/80 B. 135/85 C. 140/90 D. 145/95 0% 0% 0% 0% 130/80 135/85 140/90 145/95

  12. Outcome: Improvement in Clinical Markers A1C Levels 40.0% 35.0% 30.0% 25.0% 20.0% 15.0% 10.0% 5.0% 0.0% Less than 7 7 to 8 8 to 9 9 to 10 Greater than 10 Baseline 6 months Most Recent

  13. Outcome: Hospitalizations are declining

  14. Control Group Selection Propensity scoring to match CPS enrollees (treatments) to similar patients receiving care at non-treatment clinics (controls) in three steps: • Wave 1 treatment patients • PACE treatment patients from Wave 2 • Non-PACE treatment patients from Wave 2 Covariates used to model the propensity score: • Demographics • Health status • Utilization • Other

  15. Summary of Difference-in-Differences Results (Treatment – Control) Clinical results -11% HbA1C average change in 6 months, uncontrolled at baseline -9.3% BP % under control in 6 months, uncontrolled at baseline Utilization results Inpatient hospital visits per year per patient (12 month panel) -10% Emergency room visits per year per patient (12 month panel) -10%

  16. Which of the following is the most common medication-related problem that pharmacists identify and resolve in integrated collaborative practices? A. Medication misuse / nonadherence B. Medication safety (adverse drug events, potential adverse drug events) 0% 0% 0% C. Medication therapy . . . . . . . r . d . p a e o s n r r p o e p n v appropriateness / d a / a y e ( p s y a u t r s e e i f h m a t s n n n o o o effectiveness i i t i t a t a a c c i c i d i d d e e e M M M

  17. Medication-Related Problems Identified Through CMMI Clinical Pharmacy Program, 10/112-8/28/13 19,696 problems, 1,993 patients (9.9 per patient) Medication Misc Nonadherence, Misuse Safety Issues Appropriateness / Effectiveness

  18. Appropriateness / Effectiveness of Drug Therapy Problems Identified Through CMMI Clinical Pharmacy Program 10/1/12 to 8/28/13 (N = 8,545) Appropr. / Effect.

  19. Top Actions Made by Pharmacists to Resolve Medication-Related Problems

  20. Physician Satisfaction

  21. Unsolicited letter from AltaMed Physician ”I am writing to you today of my own accord, I have offered to make my opinion known about the excellent work that USC pharmacy team is doing without solicitation because I think pharmacy team has done an extraordinary job .” “Both Dr. Oh and Dr. Lin are extremely diligent and knowledgeable professionals , with very good rapport with their patients . I know that most of my patients actually look forward to having their sessions with the pharmacy team and have learned a great deal regarding their chronic disease self-management . Improving patient clinical parameters are an excellent proof of that.” “Dr . Oh in particular has been an integral part of the work that we do here, as a resident she goes above and beyond to make sure the patient are well care for. We have had some really mutually beneficial academic discussions and she has helped changed my practice on a few occasions while bringing in new research to my knowledge . I am really grateful to have the opportunity to work with Dr. Oh and Dr. Lin and look forward to their continued mutually beneficial relationship with us .” Clinical Pharmacy Impact

  22. What are some successes you have had in improving medication-related quality and safety for your most challenging patients?

  23. Outline • Overview of the USC / AltaMed Healthcare Innovation Award (HCIA) program from CMMI • Early results from the HCIA program • Medical leadership perspective

  24. Clinical Pharmacy WHY WE DID THIS

  25. Clinical Pharmacy WHY WE DID THIS

  26. Clinical Pharmacy WHY WE DID THIS

  27. Clinical Pharmacy WHY WE DID THIS • Doctors don’t like to follow protocols … • Pharmacists manage drug therapy better through collaborative practice agreements!

  28. Clinical Pharmacy OVERCOMING ANXIETY • Can pharmacists do this? • Will they communicate with us? • Why did I go to medical school? • Liability?

  29. Clinical Pharmacy FEEDBACK SO FAR • Staff love it • Patients love it • Quality team loves it • Unexpected benefits: - patient assistance programs - help with medication errors - staff education

  30. Clinical Pharmacy MAJOR CHALLENGE

  31. Clinical Pharmacy BUSINESS CASE • Does clinic pharmacy save money? • Is clinical pharmacy a high-value service? • If yes, how do we pay for it?

  32. Clinical Pharmacy OPTIONS • Billing policy changes • Pay for performance • Health Home Demonstration • More risk-bearing, capitated payment arrangements

  33. Outline • Overview of the USC / AltaMed Healthcare Innovation Award (HCIA) program from CMMI • Early results from the HCIA program • Medical leadership perspective • Patient perspective

  34. Patient Satisfaction Average score = 9.6 Average score = 9.7

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