Aridhia’s Journey to Software as a Service for Data Science 05/06/2014 MBN Solutions: Business Insight and Big Data Maturity in 2014 The advanced collaborative platform for healthcare and research analytics Confidential - Aridhia Informatics Ltd.
About Aridhia CLINICALLY LED, Our goals: To help healthcare providers deliver safe, efficient, effective, TECHNOLOGY DRIVEN equitable, timely and patient-centred care at the lowest cost with the best clinical outcomes. Founders: Dr David Sibbald, OBE FRSE To provide a world class sustainable, secure, collaborative Professor Andrew Morris, MB CHB, MSC, MD, FRCP environment where researchers can analyse multiple (EDIN & GLAS), FRSE, FMEDSCI complex datasets to gain insights into disease trends, treatment efficacy and new therapeutic interventions. Multi-disciplinary team: In-house team of 65 clinicians, data To partner with leading academic, government, scientists and life scientists working with pharmaceutical and biotechnology organisations on academia, government, public health, programmes that promote collaboration and drive pharma and biotech companies. applications of stratified medicine in clinical practice. Confidential - Aridhia Informatics Ltd.
Past & Present Exemplars in Health Informatics CANCER INFORMATICS & RESEARCH DECIPHER HEALTH, NHS TAYSIDE & NHS LOTHIAN MULTI-DISEASE RESEARCH SAFE HAVENS SERVICE IMPROVEMENT & PATIENT LONDON ACADEMIC HEALTH SCIENCE NETWORKS MANAGEMENT ANALYTICS NHS SCOTLAND, NHS TAYSIDE, NHS FIFE, NHS GRAMPIAN ANALYTIXAGILITY & DATA SCIENCE LAB PROPOSALS IN H2020 STRATIFIED MEDICINE SCOTLAND INNOVATION CENTRE – SCOTLAND WIDE DIABETES ANALYTICS CANCER ANALYTICS DASMAN INSTITUTE & MINISTRY OF HEALTH, KUWAIT NORTHERN SYDNEY LOCAL HEALTH DISTRICT CANCER INFORMATICS PETER MACCALLUM CANCER CENTRE, MELBOURNE Confidential - Aridhia Informatics Ltd.
Our New Business Model Confidential - Aridhia Informatics Ltd.
Moving ahead – a Platform & SaaS AnalytiXagility is a collaborative analytics platform that enables the discovery of valuable insights through the use of advanced data analysis. • Collaborate seamlessly in a secure web-accessible multi-tenant environment • Delivers new clinical research insight to improve patient outcomes and resource utilisation • Drives development & implementation of new healthcare innovations Confidential - Aridhia Informatics Ltd.
G-CLOUD Confidential - Aridhia Informatics Ltd.
Data Science – What? Confidential - Aridhia Informatics Ltd.
Data Science – Who? Confidential - Aridhia Informatics Ltd.
Data Science – Evolution of “Awesome Nerds” & “Unicorns” • Data Science in healthcare needs a multidisciplinary team involving: analysts, coders, data engineers, clinicians & managers, information governance, strategic thinkers,… • Grow in-house team and nurture technical skills & domain understanding Drew Conway @ http://www.dataists.com/2010/09/the-data-science- venn-diagram/ Hilary Mason @ http://www.forbes.com/sites/danwoods/2012/03/08/hilar y-mason-what-is-a-data-scientist/ Confidential - Aridhia Informatics Ltd.
Data Science – Role of Team at Aridhia… 1. Product Strategy & Platform Development • Scope & roadmap definition • Leadership on analytics, platform, visualisation & user experience • Development of packaged analytics & service templates • Cross company collaboration 2. Lab Based Professional Services • A multidisciplinary professional service • Agile analytics, time boxed / day rate • Collaborative working with clients on projects 3. Community Engagement • Collateral, blogs, videos, demos & examples, tutorials,... Confidential - Aridhia Informatics Ltd.
Health Knowledge Commons – Vision of the Future? Nesta Confidential - Aridhia Informatics Ltd.
Stratified Medicine Scotland Innovation Centre (SMS-IC) • Infrastructure for analysis of genomic and clinical data to develop stratification services & support clinical trials • Owned and operated by SMS-IC consortium • Integrated with the NGS Lab • Multiple roles supported • Collaborative analytics with clinical and genomic data • Cluster computing (using Hadoop) • Scalable storage • Managed data transfer, access management and audit • Secure remote access from project team’s desktop • SMS-IC provides a shared, managed service for multiple projects • Partitioned project workspaces • Software configuration management support • Production oriented Confidential - Aridhia Informatics Ltd.
SMS-IC Exemplars • Targeted deep sequencing of high grade serous ovarian carcinomas in order to inform future PARP inhibitor studies • Enabling Stratified Medicine in Early Rheumatoid Arthritis - predicting methotrexate (MTX) response and toxicity using an integrated polyomic approach • Identification of Predictive Biomarkers for Gefitinib Response in Oesophageal Cancer • A new approach to patient stratification in the development of drugs to treat chronic inflammatory diseases: linking phenotype to genotype through human tissue organocultures. Confidential - Aridhia Informatics Ltd.
Genomics England (GEL) – Let’s test the model… Map 100,000 whole genomes (or entire DNA) of NHS patients with cancer or a rare disease by 2017 Confidential - Aridhia Informatics Ltd.
GEL – 1 of 8 companies to win the SBRI competetion Confidential - Aridhia Informatics Ltd.
GEL – SBRI Enabling Technologies Phase 1 funding: March to October 2014 Collaborative approach: • Aridhia: platform development, testing annotation services • Thomson Reuters: license content and informatics support • Fios Genomics: bioinformatics • Glasgow Wolfson Wohl: bioinformatics and clinical expertise • SMS-IC: host site Main themes: • Industrialising annotation services • Integrating with the NHS Confidential - Aridhia Informatics Ltd.
GEL – AA Competition… should hear in June Confidential - Aridhia Informatics Ltd.
Thank you for listening … www.aridhia.com govstore.service.gov.uk/cloudstore/search/?q=aridhia andrew.judson@aridhia.com @aridhia, @andyjudson Confidential - Aridhia Informatics Ltd.
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