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School of Pharmacy Faculty Meeting April 29, 2011 Alternative Ways of Viewing the School Biochemical & Genetic Pathways in Disease Pharmacokinetics, Medicinal Dynamics. ADME & Chemistry & Department of Pharmacology Drug


  1. School of Pharmacy Faculty Meeting April 29, 2011

  2. Alternative Ways of Viewing the School Biochemical & Genetic Pathways in Disease Pharmacokinetics, Medicinal Dynamics. ADME & Chemistry & Department of Pharmacology Drug Design Pharmaceutical Sciences Genetic & Drug Environmental Formulation Factors in & Delivery Substance Abuse Education and Acute Care Community Care Medicine & Innovation Psychiatry Department of Pharmacy & Therapeutics Drug Safety & Critical Care & Disease State Transplantation Management

  3. Salk Hall, Commons, and Salk Pavilion

  4. Expenditures by Source 25000 Sponsored Projects Funds (Thousands) 20000 Endowments & Gifts UPMC 15000 CE University 10000 5000 0 '00 '01 '02 '03 '04 '05 '06 '07 '08 '09 '10 Fiscal Year

  5. Total Budget University Gifts and Endowments Sponsored Projects UPMC HS $7.3 Million

  6. Allocation of University and UPMC budget funds Personnel expenses Operating expenses 87% Personnel expenses

  7. Tuition Tuition less Financial Aid = Net tuition Net tuition less the required University set base = Amount over base Amount over base x 65% = SOP allocation of tuition dollars

  8. Allocation of tuition income that exceeds the base amount SOP allocation University allocation 65 % FY10 = $1,162,501

  9. PAGE (Progress At a GlancE) National Leader in Education Measure Target FY02 FY06 FY07 FY08 FY09 First-Time >95% 96.4% 90.1% 96.7% 99.0% 100% Pass Rate NAPLEX Peer Review 5 1 5 5 7 Publications (Education)

  10. Center for Clinical Pharmaceutical Sciences

  11. Clinical Pharmaceutical Sciences Sign and Website • Sign • Phil Empey – http://dev.pharmacy.pitt.edu/programs/gradprog/CSTP/index.php

  12. Area of Concentration in Research • Tom Nolin, Phil Empey, and Kerry Empey • Goal: Introduce PharmD students to the basic elements of clinical and translational research • Minimum of 15 credits: minimum 6 didactic credits and 1 or 2 rotations • Pending approval by the Provosts Office

  13. Small Molecule Biomarker Core • Focused on the use of liquid chromatography-mass spectrometry • Initiated in 2009 with instrumentation provided by a successful S10 grant from NCRR at the NIH • Partially subsidized by the Clinical and Translational Science Award (CTSA)

  14. SMBC Instrumentation Waters Acquity Ultra-Pressure Liquid Chromatography (UPLC) ThermoFisher Scientific Triple Quadrupole Mass Spectrometer

  15. SMBC UPLC/MS/MS • Short run times per sample (<6 min) • High degree of selectivity and sensitivity • Small molecules only (< 1500 molecular weight) • Not for pathway discovery or metabolomics

  16. Assays Established to Date • Endocrine Panels (including estradiol, estrone, testosterone and androstenedione) • 25-hydroxy Vitamin D 1 and D 2 • Arachidonic Acid Panels • Nicotine and Cotinine analysis • ADMA Analysis • Adenosine Pathway (cAMP) • Cytochrome P450 Probes • Multiple Drug and Metabolite Concentrations

  17. “The Rest of the Story” Graduate Program

  18. Second NRSA First CSA Revised Web Award Students Site Norman & Priscilla AFPE Fellowship Updated Creation of Third NRSA Farnsworth award Guidelines GEAR-UP First PharmD/PhD Award SP: Increase Horowitz Award Year First NRSA Track-In Award Online Program impact of TA Award Change in Paperless program Structure of Creation of GSE Reorganization New Faculty Application Student Award into Tracks Decision to Support Largest GPC Travel New Faculty Formalize/Expand number of Reduced Awards Masters Program admissions Tuition New Faculty 2008 2010 2002 2004 2006 2001 2003 2005 2007 2009 2011 First PharmD /PhD Graduate More AFPE First Awards First Graduate Student Program Fellowships Banquet Student/Post- Council New Faculty Doc Retreat First DOD Randy & Renee Chartered Award Juhl Award Major Investment Creation of Creation of by School in Pre-Doctoral Restructured Four New CSA Program Student Support Fellowships Credits Faculty Creation of CSPS Creation of Assessment Plan curricular map AAPS w/Competencies Student Chapter Collaboration with CTSI

  19. Applicants 200 Number of Applicants 150 100 50 0 2003 2004 2005 2006 2007 2008 2009 2010 2011 No Non-US n-US US US

  20. Number of Students Masters US 60 Non-US Total 50 40 30 20 10 0 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011

  21. Citizenship of Scholarship Students Non-US US 50 40 30 20 10 0 2009 2010 2011

  22. SOP Faculty Mentors 16 14 12 Number of Faculty 10 8 6 4 2 0 2006 2007 2008 2009 2010 2011

  23. Where have they gone?

  24. “The Rest of the Story” Residency Program

  25. Residency Program….. AmCare 1 st Toxicology Resident- VAMC Oncology Nephrology 1998 2000 1992 1994 1996 1991 1993 1995 1997 1999 Geriatrics Accreditation: Pharmacy Practice Managed Care Critical Care 35 Drug Info 30 25 20 15 10 5 0 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000

  26. The rest of Teaching the story… Mastery Accreditation: Transplant Residency Program ID Research Mercy Management Program 2010 2002 2004 2006 2008 2001 2003 2005 2007 2009 1 st St. Accreditation: Residency Residency Margaret 1 st Community Am Care Council Research Resident – Rite Cardiology Chartered Book Aid 35 30 CVS Caremark Forbes Pharmacy 25 20 Blackburns Pharmacy 15 10 5 0 2001 2003 2005 2007 2009 2011

  27. Number of Residents 35 30 25 20 15 10 5 0 1991 1993 1995 1997 1999 2001 2003 2005 2007 2009 2011 Graduation Year

  28. Student Video http://www.youtube.com/watch?v=kLkkpidvzRo&feature=fvsr

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