Clinical Identification of… Delirium Delirium KIE L ADAM MORRIS, DO BROADL AWNS GE RIAT RICS
Custo mary F inanc ial Disc lo sure S lide I don’t have any c onflic ts of inter est to disc lose whatsoever , inc luding (but not limited to) financ ial r elationships.
My lofty goals for the ne xt 15 minute s… c o nve y impor tanc e o f the to pic define de lirium & de me ntia re vie w c linic al pr esentation re vie w evaluation o f de lirium re vie w etiologies to c o nside r addre ss tr eatment o f de lirium re vie w pr evention strate g ie s e nd with a c ase if time allo ws
Signific anc e – why disc uss de lirium? It’s c ommon , so we ’ re all pro bably g o ing to se e this at so me po int. Clinic se tting . Ho spital se tting . L o ng -T e rm Care se tting . Our pe rso nal live s. I t c an happen to anyone , no t just g e riatric patie nts. But it’ s partic ularly pr ic populations . evalent in ger iatr Ne arly 30% at so me po int during a ho spitalizatio n ( F ranc is, J., De lirium in Olde r Patie nts, JGS ) Co nse que ntly may le ad to a false positive impr ession of dementia . De lirium o fte n subtle & vague sign of ser ious under lying pr oblem .
Ho w do we de fine Delirium? Delirium? Co mplic ate d, but c o nso lidating e le me nts fro m UpT o Date , Unite d He alth Partne rship, and DSM-V, de lirium is… …an ac ute de c line fr om base line atte ntion/ c ognition assoc iate d with psyc homotor agitation that is c linic ally- pr ovoke d and (ofte n) r e ve r sible . I t c an c e rtainly be c o nside re d a syndro me witho ut a c le arly de fine d unifying patho physio lo g y. Pe rhaps use ful to think o f de lirium as a state o f ac ute c o g nitive imbalanc e , whic h is c le arly muc h mo re e asily induc e d in e lde rly patie nts partic ularly tho se with de me ntia.
So the n, ho w do we de fine Dementia ? Chr onic de c line in multiple do mains o f base line c o g nitio n ( me mo ry, le arning, atte ntio n, language , e xe c utive func tio n ) to a de g re e that inte rfe re s with individual func tio n ( ADL s ) and is no t fully e xplaine d by s/ I ADL alte rnative o r c o nc urre nt diag no se s ( e .g. ADHD, De pre ssio n, e tc ).
Distinguishing De lir ium & De me ntia Delirium Delirium Dementia Abrupt Gradual Onset Ho urs-days Mo nths-ye ars T iming I mpaire d Pre se rve d in e arly stag e s Attention / Or ientation F luc tuating No rmal L vl of Awar eness I nc o he re nt Dise ase & Stag e L anguage Diso rg anize d Speec h De pe nde nt Variable Sho rt-T e rm, e arly Memor y Impair ment F luc tuating L o ng -T e rm, late r
Signs & Symptoms n additio n to de lirium c rite ria disc usse d be fo re I F amily may say pt is “no t he rse lf” o r “o ut o f it”. Alte rnative ly, may be ag itate d/ re stle ss. F luc tuating c o urse ; may appe ar luc id o r “no rmal” . ounds ! Car e ful not to le t this fool you on mor ning r
De lir ium may be the only sign of se r ious illne ss in the e lde r ly!
CC: “Ma ain’t quite he r se lf for 3 days.” Take this chief complaint seriously! Take this chief complaint seriously! y o f what’ s be e n g o ing o n. Obtain a good histor Ask abo ut spe c ific e le me nts o f “ain’ t quite he rse lf.” Ask abo ut physic al sympto ms the y’ ve no tic e d. Ask abo ut sig nific ant e nviro nme ntal c hang e s. ough physic al , inc luding ne uro e xa m. Per for m a thor Asse ss using c linic al tools spe c ific to de lirium, e .g . bCAM (ne xt slide ). Dire c te d testing , e .g . labs, imag ing , L P, e tc .
B rie f C o nfusio n A sse ssme nt M e tho d
c ale e datio n S Ric hmo nd Agitatio n-S
e ntial Diagnosis Mne monic s… Diffe r
Drugs may c ause o r pro lo ng de lirium. Analgesic s – NSAI Ds, Opio ids Antibiotic s – e .g . fluo ro quino lo ne s Anti-c holiner gic s Anti-c onvulsants essants , e .g . mirtazapine Anti-depr Anti-Hyper tensives Anti-spasmodic s (MSK) – e .g . c yc lo be nza prine Anti-spasmodic s (GI) – e .g . dic yc lo mine Cor toc oster oids Hypnotic s – Ba rbs & Be nzo s
Pr e ve ntion is not always possible , but we c an tr y!
Ho w do we tr e at de lirium? F ix the glitc h!
hank yo u! T Questions?
Sources UpT o Date : “Diag no sis o f de lirium and c o nfusio nal state s” UpT o Date : “Pre ve ntio n, tre atme nt, and pro g no sis o f de lirium…” Unite d He alth Ne two rk: “De lirium Pre ve ntio n and Manag e me nt”
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