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CS 466 Introduction to Bioinformatics Instructor: Wesley Wei Qian - PowerPoint PPT Presentation

Nov 06, 2023 •246 likes •708 views

CS 466 Introduction to Bioinformatics Instructor: Wesley Wei Qian Probability and Statistics Random Variables and Expectations Random Variable Random Variable Probability distribution Joint distribution Marginal distribution Independent

  1. CS 466 Introduction to Bioinformatics Instructor: Wesley Wei Qian

  2. Probability and Statistics Random Variables and Expectations

  3. Random Variable

  4. Random Variable

  5. Probability distribution

  6. Joint distribution

  7. Marginal distribution

  8. Independent variables

  9. Continuous probability distribution

  10. Continuous distribution: density function

  11. Joint distribution

  12. Marginal distribution

  13. Expected value

  14. Expectation

  15. Some properties of expectation

  16. Mean, Variance and Covariance

  17. Examples

  18. Properties of variance and covariance

  19. Properties

  21. Statistics

  22. Mean

  23. Standard deviation and Variance

  25. Normalization

  26. Correlation

  27. Correlation coefficient Also called Pearson Correlation Coefficient

  29. Correlation coefficient vs Relationship

  30. Correlation and Causality monthly data Ice Cream vs Drowning

  31. Ice Cream vs Drowning

  32. Ice Cream vs Drowning

  33. Chocolate vs Nobel Prizes credit: NEJM, 2012

  34. Gene expression analysis sample gene

  35. Correlation analysis

  36. Weighted Edit Distance revisit

  37. BLOcks SUbstitution Matrix (BLOSUM) amino acids

  38. BLOcks SUbstitution Matrix (BLOSUM)

  44. How to get a good substitution score?

  46. BLOcks SUbstitution Matrix (BLOSUM) amino acids

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