corus
play

CORUS Co-receptor usage as a marker for specific HIV diagnostics - PowerPoint PPT Presentation

Co-receptor diagnosis the clinical perspective CORUS Co-receptor usage as a marker for specific HIV diagnostics with high sensitivity CXCR4 CORUS CORUS CORUS MARAVIROC Genotypic assay Moyle 2005 JID 191;866-72 TROFILE TROFILE


  1. Co-receptor diagnosis – the clinical perspective CORUS Co-receptor usage as a marker for specific HIV diagnostics with high sensitivity

  2. CXCR4 CORUS

  3. CORUS

  4. CORUS

  5. MARAVIROC

  6. Genotypic assay

  7. Moyle 2005 JID 191;866-72 TROFILE

  8. TROFILE

  9. TROFILE

  10. Trofile - drawbacks • No detection of minority variant populations • Testing only in California or France • Labor intensive and expensive • Time consuming

  11. CORUS – research goals Development of diagnostic assay for selective detection of X4-tropic minorities in HIV-1-infection Strengths of a new assay should include: • Fast and easy performance • Applicability in vitro • Suitability for routine diagnostics

  12. CORUS - Subprojects Univ. Cologne GSH Univ. Duisburg-Essen Univ. Düsseldorf SIEMENS HZI DIAGNOSTICS

Recommend


More recommend