Corporate presentation Index: Slide Number Background-2 Core Service Capabilities-3 Inside our Labs-4 Our Team-5 Valuation-6 Contact Information-7
Background May 2003 Dec 2008 Feb 2013 Mar 2017 Relocated to State-of-Art Re-organization Protein Ark Incorporated and rename to facilities at The acquired as Protealysis BioServUK Innovation BioServUK Centre A specialist CRO/CMO company with expertise in the production and processing of bio-molecules, primarily antibodies. Using state of the art technology and working under an ISO 9001 quality system, we provide products to biotech, pharma, IVD manufacturers and research institutes. Limited competition. Primary manufacturer positioned to offer de novo Ab production and bulk manufacturing. BioservUK and its key personnel have a strong, established reputation in UK. 2
Core Service Capabilities 10 mg – 100g 200g 4,000L 200L 20L Typical purified mAb Maximum mAb Maximum cell Maximum cell Wave bag batch quantity of customer capacity per culture volume per culture volume in a capacity orders (typical 20mg/L annum annum single batch production) Custom de novo monoclonal and polyclonal antibody production with bespoke target • screening. Production of bulk mAb from hybridomas and other proteins expressed in mammalian • culture, e.g. CHO, HEK 293, NSO cells. Extensive experience in cell line recovery and growth optimization. • Adaptation to protein free medium (ADCF; Free of Animal Derived Components) – • regulatory compliant, increased yield by up to 30%. Routine Purification: Protein A/G chromatography; Immuno-affinity chromatography; • IMAC 100% owned Highly validated ELITE Antibodies (catalogue antibodies) focused on • Hormonal Control, Fertility and related Cancers. 3
Inside Our Labs 4 x large scale 3 x high 7 x CO 2 1 x wave bag • • • • roller capacity incubators (20L) incubators centrifuges 4 x laminar 1 x high 3 x -80°C 2 x high capacity • • • • liquid nitrogen flow hoods volume freezers dewars tangential cross flow rig 4 x purification 4 x shaker 2 x gel doc 5 x high power • • • • Leica microscopes systems incubators systems 4
Our Team Dr Mike Brownleader CEO/Sales Director Dr Andy Wright Dr Simon Smith Facility Manager Business Alex Fridgant George Alexander Development (Founder) Marketing Manager Accounts & Book-keeper Caroline Daye Ian Philips Dr Simon Tanley Dr Tom Lovewell Cell Culture DSP/Kits/QC Kits/Bacteria Kits/Mammalian Expression/DSP Expression/DSP (ISO 9001:2015) 5
Business Vision and Valuation Vision Provide the IVD and research markets with high-quality antibodies and custom services to support advances in clinical diagnostics and improve healthcare Realise the market value from IVD Expand our catalogue of 100% Strategy customers for whom owned monoclonal antibodies for Target early phase Drug validation is ongoing the research and IVD markets Discovery Expand role as CMO/CRO by bolting on new services and products to existing customers worldwide and lead generation for new, emerging and under-developed markets Long-term Objectives Become a one-stop shop for life science customers by working synergistically with Protein Ark in order to provide a gene sequence to purified protein, scale up capability 6
Contact Information BioServUK Ltd Mike Brownleader – CEO and Sales Director The Innovation Center 217 Portobello T: +44 (0) 7917 806 666 S1 4DP E: mike@bioservuk.com Sheffield, UK Andy Wright – Facility Manager T: +44 (0)114 224 2235 E: info@bioservuk.com T: +44 (0) 7949 854 993 W: www.bioservuk.com E: andy.wright@bioservuk.com 7
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