CO COVID ID-19 19 Where are we with COVID-19? What can you tell us about the CO COVID-19 19 vaccine ine?
COVID-19 in Arizona • 182,203 cases overall – Confirmed and probable – A person is counted once, no matter how many tests • 3,932 deaths Data updated: 8/5/20
Links to Data Sources • AZ Department of Health Services – Data Dashboard • CDC Data • Johns Hopkins University
Summary of COVID-19 Vaccines August 5, 2020 Presenting To TAPI Tips Karen Lewis, M.D. | Immunization Medical Director
Coronaviruses • Common colds (4) • Severe Acute Respiratory Syndrome (SARS) • Middle East Respiratory Syndrome (MERS) • 2019 Novel Coronavirus CDC PHIL 18110
Novel Coronavirus Naming COVID-19 SARS-CoV-2
Spike Protein Used to Enter Cell PHIL #18115
Vaccine Safety • Preclinical animal studies • Phase 1, 2, 3 • Food and Drug Administration approval • CDC recommendations • Post-licensure monitoring
mRNA and DNA in Cells PHIL #22200
COVID-19 Vaccine Non-replicating Viral Vector Chimpanzee Adenovirus DNA SARS-CoV2 Spike Protein DNA Chimp Adenovirus DNA SARS-CoV2 Spike Protein Chimp Adenovirus DNA mRNA mRNA mRNA Spike Proteins
mRNA COVID-19 Vaccines Pfizer diagram
mRNA Codes for Spike Protein Pfizer diagram
COVID-19 Vaccines Spike Proteins + Adjuvant Spike proteins
DNA Vaccine • DNA plasmid with instructions for spike protein • Intradermal • Room temperature www.prnewswire.com
COVID-19 Vaccines Operation Warp Speed FDA EUA RESOURCES COLLABORATION APPROVAL
Still Under Study • One or two doses • Handling requirements • Fever, local reactions, etc. • Efficacy • Length of immunity
Flu Shots for Everyone This Year! www.vaccinefinder.org
Po Poll What are your thoughts on recommending the COVID-19 vaccine when it’s available?
CO COVID ID-19 9 Impa pact ct on Vaccine ccines s – Ca Catch ch Up! p! • • • • • • •
Odds ‘n Ends 1 2 3 4
Ho How do I tr track ack down n shot t rec ecords? rds?
If a pa parent ent co come mes s in in asking king to to get et sch chool ool- required vaccines, isn’t that a “win”? A B C
Te Tempe peratures atures How long can my vaccine stay out of temp range?
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My My na name me is Ma Machr hrina! na!
Whe hen n do do I I repor ort t to o VA VAER ERS? S?
When en in in doubt, t, RE REPO PORT. RT. Whe hen n do do I I repor ort t to o VA VAER ERS? S?
Best Be t Pr Practi ctices ces in in Immuniza unization tion Del elivery ivery in in Ar Ariz izona na What would it take for 90% 0% of my patients to be up to dat ate on their immunizations?
Dr. Daniel T. Cloud Awards 30
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