Clinical Research | Clinical Care Investigator Driven Industry - PowerPoint PPT Presentation

Clinical Research | Clinical Care • Investigator Driven • Industry Sponsored Breakfast-Wednesday April 06, 2016 • Technology and Innovation • Registries Colleen O’Connell, MD FRCPC Research Chief – Stan Cassidy • Discoveries Centre for Rehabilitation Assistant Professor – • Best Practice Dalhousie Faculty of Medicine/Memorial Development University

Symbiotic Mutualism Breakfast-Wednesday April 06, 2016

Clinical Research Breakfast-Wednesday April 06, 2016

Practice-based Research • Research conducted by providers in clinical Breakfast-Wednesday April 06, 2016 practice • Final step in translational research continuum

Patient-oriented • 17 pharmacologic trials – 3 investigator driven – >1M Breakfast-Wednesday April 06, 2016 – Current 11 staff PT funding (4 trials) • 9 technology trials – 100K CFI eksoskeleton – Biotone – 2.4M – Industry (Myndmove, Sensimat, B-Temia)

Recent Grants - 2016 • ALS Discovery Grant – SCCR/Vitalite – 100K • ALS Clinical Management – SCCR/McGill – Breakfast-Wednesday April 06, 2016 200K + matching industry • RHSCIR - $40K • CFI – 100K • CNDR - $16K • Myndmove - $200K (4 sites)

Outcomes and health services • Canadian ALS Registry Breakfast-Wednesday April 06, 2016 • Canadian NMD Registry • RHISCIR • > 250K to date • Knowledge Mobilization • 3 PT staff positions Network • ~ 55K annually

Evidence Based Practice Breakfast-Wednesday April 06, 2016

Epidemiological and behavioural • ALS-NB Cluster Study • ALS Quality of Life Breakfast-Wednesday April 06, 2016 Validation • ALS Research Readiness Summer research students • • Canadian ALS Registry National • presentations/publications • Canadian NMD Registry • RHISCIR

Benefits to Patients and Systems • Improvements in Infrastructure: – Access to new equipment and technology – Access to novel therapies Breakfast-Wednesday April 06, 2016 – Acquisition of new skills • Improvement in Outcomes: – Greater adherence to treatment guidelines – More use of evidence-based practice • Staff attraction/retention • Improved research literacy • Culture of enquiry and critical appraisal of practice

Canadian MS Survey Breakfast-Wednesday April 06, 2016

New Brunswick Prevalence Multiple Sclerosis: 1300-1800 Amyotrophic Lateral Sclerosis: 60 patients Breakfast-Wednesday April 06, 2016 SCI – 30 new annually Muscular Dystrophy and related: 250 Parkinsons Disease, Huntingtons, Spinocerebellar Ataxias….

Breakfast-Wednesday April 06, 2016

Research Networks • Canadian ALS Clinical Trials and Research Network Breakfast-Wednesday April 06, 2016 • Rick Hansen Institute Spinal Cord Injury Research Leadership Team • SCI – Knowledge Mobilization Network • CCIC • Atlantic Mobility Action Project • End-MS Research Network • Canadian Neuromuscular Disease Research Network • Canadian Neuropulmonary Research Network

Conclusion • Clinical research compliments clinical practice Breakfast-Wednesday April 06, 2016 • Creates jobs, brings in equipment, expertise and positive outcomes • Participation in national/international research networks and registries can facilitate participation and improve efficiencies

Clinical Research | Clinical Care Investigator Driven Industry - PowerPoint PPT Presentation

Clinical Research | Clinical Care Investigator Driven Industry Sponsored Breakfast-Wednesday April 06, 2016 Technology and Innovation Registries Colleen OConnell, MD FRCPC Research Chief Stan Cassidy Discoveries

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Clinical Research | Clinical Care Investigator Driven Industry - PowerPoint PPT Presentation

Clinical Research | Clinical Care Investigator Driven Industry Sponsored Breakfast-Wednesday April 06, 2016 Technology and Innovation Registries Colleen OConnell, MD FRCPC Research Chief Stan Cassidy Discoveries

A Typical Organogram of Clinical Research Organization Clinical Research Clinical Data

Tracey L. Smith, Ph.D. Associate Director for Improving Clinical Care Terri Barrera, Ph.D.,

Clinical Care vs. Clinical Research: The Therapeutic Misconception Howard Brody, MD, PhD Center

Clinical Research Office: Services From To of a Clinical Research Study C LINICAL AND T

Clinical Research Capabilities Bioavailability &amp; Bioequivalence Studies Clinical Research

Clinical Integration and Collaborative Care: Clinical Integration and Collaborative Care:

Chronic disease care plans &amp; Clinical templates At the practice I also created 50 robust

Integrating PROs for Clinical Care &amp; Research Rachel Hess, MD, MS @ r h e s s m d EVERY

Bryce B. Reeve, PhD bbreeve@email.unc.edu Can we collect research quality,

Genomics in Patients with Hispanic ancestry - Pharmacogenetics in Hispanics and Its clinical

Understanding the Clinical Research Process and Principles of Clinical Research Introduction

The Transformation of Clinical Research in Vasculitis Through the Rare Diseases Clinical Research

The How, Where, and Why of Clinical Trials ERIN HAWKS, CCRC Lost in the woods . Standard of

Breaking Into the Clinical Research Field A How-To Guide to Jump Start your Clinical Research or

1 RATIONALE FOR PLASMA LEVEL MONITORING PRESCRIBED DOSE ADHERENCE ABSORPTION MOST TISSUES

Welcome to the HIV-TB Research Symposium MRC Clinical and

Clinical Research India: the Need for Education &amp; Training Clinical trials were initiated

Orientation to Clinical Research at USC Randolph Hall Vice President, Research Growing Clinical

NIAID TB Clinical Research Agenda Current and Future OCTOBER, 2011 Clinical Research Funding

A Clinicians View of Complicated Spiritual Grief Bridging Research and Clinical Practice

CLINICAL RESEARCH AND ACADEMIC CLINICAL TRIALS MASARYK MEMORIAL CANCER INSTITUTE DEPARTMENT OF

Clinical study: Clinical presentation and patterns of care for short-term survivors of malignant

Primary Care Clinical Lead 1 Primary Care Development Introduction: Clinical Lead: Dr

CADET: Clinical &amp; Cost Effectiveness of Collaborative Care for Depression in UK Primary Care:

Clinical Research Capabilities Bioavailability & Bioequivalence Studies Clinical Research

Chronic disease care plans & Clinical templates At the practice I also created 50 robust

Integrating PROs for Clinical Care & Research Rachel Hess, MD, MS @ r h e s s m d EVERY

Clinical Research India: the Need for Education & Training Clinical trials were initiated

CADET: Clinical & Cost Effectiveness of Collaborative Care for Depression in UK Primary Care: